Streptomyces kanamyceticus: CP970_21030
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Entry
CP970_21030 CDS
T06849
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ska
Streptomyces kanamyceticus
Pathway
ska00280
Valine, leucine and isoleucine degradation
ska00640
Propanoate metabolism
ska00785
Lipoic acid metabolism
ska01100
Metabolic pathways
ska01110
Biosynthesis of secondary metabolites
ska01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
ska00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CP970_21030 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CP970_21030 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP970_21030 (pdhA)
Enzymes [BR:
ska01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
CP970_21030 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
XFP_N
Motif
Other DBs
NCBI-ProteinID:
QEU93065
UniProt:
A0A5J6GGN7
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Position
complement(4952721..4953866)
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AA seq
381 aa
AA seq
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MTVMEQRGAYRPTPPPAWQPRTDPAPLLPDAEPYRVLGTDAAQKADPGLLRRLYAELVRG
RRYNTQATALTKQGRLAVYPSSTGQEACEVAAAFALEERDWLFPSYRDTLAAVARGLDPV
SALTLLRGDWHTGYDPREARIAPLSTPLATQLPHAVGLAHAARLKGDDVVALAMVGDGGT
SEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVDGN
DAAAMHEVLSEAVARARAGGGPTLVEAVTYRMEAHTNADDATRYRPDAEVTAWRDHDPIL
LLERELTERGLLDDDLKRQAGDDAEAMAADLRGRMNQDPQLDPMDLFTHVYAEQTSQLRE
QAAQLRAELEVASEEAEEEAR
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatggagcagcggggcgcctaccggccgaccccgccccccgcttggcagccc
aggacggaccccgcgccgctgctgccggacgcggagccgtaccgagtccttggcaccgat
gccgcgcagaaggccgacccggggctgctgcgccgcctgtacgcggagctggtccgcgga
cgccgctacaacacgcaggcgacggccctgaccaagcagggcaggctcgccgtctacccg
tcgagcaccgggcaggaggcgtgcgaggtcgccgcggcgttcgccctggaggagcgggac
tggctctttcccagctaccgggacacgctcgccgcggtcgcccgcggcctcgacccggtc
agcgcgctgacgctgctgcgcggcgactggcacaccgggtacgacccccgcgaggcccgc
atagcgccgctgagcacgccgctcgcgacccagctcccgcacgccgtgggcctcgcgcac
gccgcccgcctcaagggtgacgacgtggtcgcgctcgccatggtcggcgacggcggcacc
agcgagggcgacttccacgaggcgctgaacttcgcggccgtgtggcaggcgcccgtcgtc
ttcctcgtgcagaacaacggcttcgcgatctccgtgccgctcgccaagcagaccgcggcc
ccctccctcgcgcacaaggccgtggggtacggcatgccggggcgcctggtggacggcaac
gacgcggccgcgatgcacgaggtgctgagcgaggcggtggcccgggcacgcgcgggcggc
ggcccgaccctcgtcgaggcggtcacgtaccgcatggaagcgcacacgaacgccgacgac
gccacgcgctaccgccccgacgccgaggtcacggcctggcgtgaccacgacccgatcctc
ctcctggagcgggagctgacggagcgcggactcctggacgacgacctgaagcggcaggcg
ggcgacgacgcggaggccatggcggccgacctgcgcgggcgcatgaaccaggacccccag
ctcgaccccatggacctcttcacgcacgtgtacgccgagcagacctcccaactgcgggag
caggcggcgcagttgcgggccgagctcgaagtggcctcggaagaggcggaggaggaagcg
cgatga
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