Shewanella khirikhana: STH12_00433
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Entry
STH12_00433 CDS
T06711
Symbol
thrA
Name
(GenBank) Bifunctional aspartokinase/homoserine dehydrogenase 1
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
skh
Shewanella khirikhana
Pathway
skh00260
Glycine, serine and threonine metabolism
skh00261
Monobactam biosynthesis
skh00270
Cysteine and methionine metabolism
skh00300
Lysine biosynthesis
skh01100
Metabolic pathways
skh01110
Biosynthesis of secondary metabolites
skh01120
Microbial metabolism in diverse environments
skh01230
Biosynthesis of amino acids
Module
skh_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
skh_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
skh_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
skh00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
STH12_00433 (thrA)
00270 Cysteine and methionine metabolism
STH12_00433 (thrA)
00300 Lysine biosynthesis
STH12_00433 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
STH12_00433 (thrA)
Enzymes [BR:
skh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
STH12_00433 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
STH12_00433 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AZQ09584
LinkDB
All DBs
Position
499035..501539
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AA seq
834 aa
AA seq
DB search
MFLGQARQIGVAKMKVMKFGGTSLANWQRFEMAANIVADAAKASQVAAVLSAPATVTNGL
LEMVDVAVAGGDFEAVLGRVKGVFESLFADACRHRPKVCSKALADALASQVSVWQTRLQG
VSLLGECPDGVRAEIVVSGERLSTELMVALMNADGPGADKLDPRALFLAHGTPLESVVDI
AVSKPRFKALALQSKRVWVMPGFTAADEQGRTVTLGRNGSDYSAAVLAACLDAQSCEIWT
DVDGVYNTDPRVVADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFN
PSAPGTLVSNAADETGLQVKAISSLDNQTMFDVSGPGMKGMVGMASRTLGAIARAGVSVS
LITQSSCEYSISFCVSGNDAAKVKSALQLEFELELKSELLEPLEARDGLAIVSLIGDGMR
THKGVAAKFFSALAQSGVNIVAIAQGSSERSISAVVEQRKVQNAIGACHQRFFDVQQYLD
VFLVGAGNVGAGLLAQVKNQAEALKELHISIRVCGIANSRKMLLDARGIDLGNWQGLLAD
SETDCDLGAMLSWAKEKQLLNPVLVDCTSSSAVADRYLEVMEAGMHVVTPNKKANTRDLD
YYRALREAALRNRRQFLYETNVGAGLPVIDNLKKLLCAGDKLHRFNGILSGSLSFIFGKL
DEGMSLSEATGIARDKCFTEPDPRDDLSGMDVARKVLILAREVGMELELEDVVVDSVLPA
TFDASGDVNTFMANLPKADAEIAAMVENARSEGKVLRYVGQIDESGCRVSIQAVGPEDPL
FSVKGGENALAFYSRYYQPIPFVLRGYGAGTDVTAAGAFADLLRTLNWTREVSL
NT seq
2505 nt
NT seq
+upstream
nt +downstream
nt
ttgtttctggggcaagcgaggcagattggagtagcaaagatgaaagtcatgaagtttggg
ggtacctcgctggccaactggcagcgtttcgaaatggcggccaatatcgtcgccgatgcg
gctaaagcgtctcaggtggcggccgtgttgtctgcacccgctactgtaaccaacggtttg
ttggaaatggtggatgtggccgtggccggcggcgattttgaggccgtgctgggaagggta
aagggcgtgtttgagagcctgtttgccgatgcctgtcgccatcgtcccaaggtctgtagc
aaggcgctggccgacgcgctcgcatctcaggtcagtgtctggcaaacccgcttgcaaggg
gtgtcgcttttgggggagtgccctgatggggtgcgcgctgaaatcgtggtctccggcgag
cggctgtccactgagttgatggttgccctgatgaatgccgatggccccggcgccgataag
ctggaccccagagccctgtttctggcccatggcacaccgctggaatctgtggtggatatc
gctgtcagtaagccaagatttaaggctctggcgctgcaaagtaaacgtgtgtgggtaatg
cctggctttaccgccgccgacgagcagggccgcaccgtgaccctcgggcgcaatggctct
gactattccgccgctgtgctggccgcttgcctcgatgcccaaagctgtgagatctggacc
gacgtggatggggtgtacaacaccgacccccgggtggttgccgatgccaagctgttgtcg
cagctctcatatcaggaggccatggagctgtcttactttggcgccaaggtgctgcacccc
aagaccatagcgcccatcgctcagttccatatcccttgctacatcaaaaacagttttaat
ccgtcggcgccgggcaccctggtatccaacgccgccgatgagaccgggctgcaggtaaaa
gccatctccagcctcgacaaccaaaccatgttcgatgtgtccggccccggcatgaaaggc
atggtgggtatggccagccgcaccctgggcgccatcgcccgtgccggtgtatctgtgtcg
cttatcacccaaagctcctgtgaatactccatcagcttttgcgtttccggtaacgatgct
gccaaggtgaaatcggcgctgcagctcgagtttgaacttgaactcaagagcgaactgctt
gagccgctggaggcccgtgacggcctggcgatcgtgtcacttatcggcgatggcatgcgc
acccacaagggcgtagcggccaagtttttctcggcgctggctcagtcgggcgtgaacatt
gttgctatcgcccagggctcctctgagcgctctatctctgcggtggtggagcagcgcaag
gtacagaatgccatcggcgcctgtcatcagcgcttcttcgatgtgcagcaatatctggat
gtgttcctggtaggcgcaggtaatgtgggcgccggactgctggcacaggtgaagaaccag
gccgaagcgctcaaagagctgcatatcagcatccgtgtttgtggtatcgccaattcgcgc
aagatgctgctcgatgcgcgcggcattgaccttggcaattggcaggggctgctcgctgac
agtgaaaccgattgcgatctgggcgccatgctctcgtgggccaaagaaaagcagctgctg
aatccggtgctggtggactgcacctcgtcttcagccgtagccgaccgatatcttgaggtg
atggaagcgggcatgcacgtggtgacgcctaataagaaggccaatacccgtgatttggat
tactaccgggcgctgcgcgaagcggcgctcagaaacagacgtcagttcctgtatgagacc
aacgtcggcgccggattgccggttatcgataatctgaaaaagctgctctgcgccggtgat
aagttgcacagattcaatggcatactctcaggttcgctgtcgtttatctttggcaagctg
gatgagggcatgagcctgtcggaagcgaccggcatcgcccgtgacaaatgctttaccgag
ccggatccaagagacgatctctcaggtatggatgtggcccgcaaggtgcttattctcgcc
cgtgaggtgggaatggagcttgaacttgaggatgtggtggtggattcggtgctgccagcc
actttcgatgccagcggcgatgtaaatacttttatggcgaatctgcccaaggcggacgcc
gagattgccgctatggtggaaaatgcccgcagcgagggcaaggtgctgcgctacgtgggg
caaatcgatgagtcaggctgccgggtgagcattcaggctgttgggcctgaggacccactt
ttcagcgtgaaaggcggcgagaatgcgctcgccttctatagccgttactatcaacctatt
ccgtttgttctgcggggatatggtgcgggtactgatgtgactgcggccggcgcctttgcc
gatttgctgcgtaccctgaactggacccgtgaggtgagtttatga
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