Salinivibrio kushneri: FCN78_02575
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Entry
FCN78_02575 CDS
T05956
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sks
Salinivibrio kushneri
Pathway
sks00260
Glycine, serine and threonine metabolism
sks00261
Monobactam biosynthesis
sks00270
Cysteine and methionine metabolism
sks00300
Lysine biosynthesis
sks01100
Metabolic pathways
sks01110
Biosynthesis of secondary metabolites
sks01120
Microbial metabolism in diverse environments
sks01230
Biosynthesis of amino acids
Module
sks_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sks_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sks_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sks00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FCN78_02575 (thrA)
00270 Cysteine and methionine metabolism
FCN78_02575 (thrA)
00300 Lysine biosynthesis
FCN78_02575 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FCN78_02575 (thrA)
Enzymes [BR:
sks01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FCN78_02575 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FCN78_02575 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QCP01382
LinkDB
All DBs
Position
1:531513..533972
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSLADAERFSRAADIIVSNQGQSDVSAVLSAPAKVTNILVSVVDNTVKHGEA
ELPLKELEQLFADLFHGLAERQPNLDTQPLFDKLTRSLGQLRQYVHGMSLLGLCPDSTYA
RVVSKGERLSVAAMHALLEARGYAVFDIDPVAYFAASGSHLSAEVDIEASSQRFKQSPVP
AKHIGLMPGFMAGNENGELVTLGRNGSDYSAAVLAACVRAECCEIWTDVDGVYNCDPRLV
PDARLLKSLSYQEAMELSYFGAKVLHPKTIAPIARFHIPCLIKNTANPQAEGTLIGEDSG
EDKLAIKGITTLSDLSMVNLSGPGMKGMVGMASRVFGAMSSAGVSIVLITQSSSEYSISF
CIQSRDKEKADKVLSNHFELELKDGLLEPVEFMDNLSIVSLVGDGMRTSKGVASRFFTSL
AEVNVNIVAIAQGSSERAISAVVPSERVSEAVKACHENLFNSQHHLDVFIVGVGGVGGEL
IEQIRRQQAKLQQQGIVMRVCGLANSKGMWLNSQGIDLNSWRDELPNHLSTFSLAGMIQL
VQRNHIINPVLIDCTADQQVAEQYADFLRAGFHVITPNKKANTSSMAYYHQLRQAARATH
RKFMYETTVGAGLPVIENLQNLIAAGDELSRFSGILSGSLSHIFGKLDDGASFSEATQVA
RENGFTEPDPRDDLSGMDVARKLLILAREAGMELELDDVEVEPALPPGFDQSGDVESFMA
RLPQADDYFKQWSEEAAKEGKVLRYIGGIEDGRCFVKIQAVSDDDPMNKIKEGENALAFY
SRYYQPIPLVLRGYGAGTAVTAAGVFADLMRTLGWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagttttaaaatttggtggcacgtcgcttgccgatgctgagcgcttcagccgcgct
gccgatatcattgtcagtaaccaagggcagagcgatgtatctgccgtgttatccgccccc
gcgaaagtcacaaacattctcgtttctgtggtcgataatacggtcaaacatggtgaagcg
gagttgccgcttaaagagctcgagcagcttttcgccgatttgttccatggtcttgctgag
cggcagcccaaccttgatacccagccacttttcgataaattaacgcgtagtctcggccaa
cttcgtcaatatgtgcatggcatgagtttgttgggcctttgtcccgatagcacttatgcg
cgcgtggtcagcaaaggcgagcgtttatcagtcgccgcaatgcatgcgttgctcgaagcg
cgtggctatgcggtatttgatatcgacccagtggcatactttgccgcttccgggagccat
ctaagtgctgaagtagacatcgaagcctcatcgcaacgtttcaaacaatcacccgttcca
gctaagcacattggcctgatgccagggtttatggcgggaaacgaaaatggcgagctggtg
acccttggacgcaatggctctgattactcggcggcggtactcgcggcgtgtgtacgtgcc
gagtgttgcgagatttggacggatgtcgacggtgtttacaactgtgatcctcgcctcgta
ccggatgcgcgcttgcttaaatcattgagctatcaagaagcgatggagctgtcttatttt
ggcgccaaagtattgcatcccaaaaccattgcgcccatcgcacgcttccacatcccttgt
ttaatcaaaaataccgccaacccgcaagccgaaggcaccttaattggcgaagacagtggt
gaggataagctggccattaaagggatcactacgttaagcgatctgagtatggtcaaccta
tcaggcccgggtatgaaaggtatggtagggatggcatcacgcgtgtttggtgcgatgtca
tcggcgggggtgtcaattgtgttgattacccaatcttcttctgaatacagcatcagtttt
tgtattcaaagccgggacaaagaaaaagccgataaggtgctgagtaaccattttgagctt
gaactgaaagatggtctgctcgagcctgtcgagtttatggataacttgtcgattgtctcc
ttggtaggcgatggtatgcgcacttcgaaaggtgttgcctctcgctttttcacctcgttg
gcggaggtaaacgtcaatatcgttgcgattgctcaaggttcatcggagcgtgctatctct
gcggttgttccttcagagcgggtctctgaagcggttaaagcctgtcatgaaaacttattt
aatagccaacatcacttggatgtatttatcgtcggtgtcggtggcgtgggcggtgagctg
attgagcaaatccgtcgtcagcaagccaagctccagcaacaaggcattgtgatgcgggtc
tgtggtttagcgaacagcaaagggatgtggctgaatagccaaggcattgatttgaatagc
tggcgcgatgaacttcccaaccacctatcgacgtttagcctcgcggggatgatccagctg
gttcagcgcaatcacatcattaaccctgtgttgatcgattgcaccgccgatcagcaggtc
gccgagcaatatgctgatttcttgcgtgcaggctttcacgtgatcactcccaacaagaaa
gccaataccagtagcatggcttactatcaccagttgcgtcaggcggcccgcgcgactcac
cgcaaatttatgtatgagaccacggtgggtgcaggtttaccggtgattgaaaatctacaa
aacttgattgcggccggggatgagctgtcacgcttttctgggattttatcaggatcgctt
tcccacattttcggcaagttagatgatggcgccagctttagcgaggcgacccaggtcgca
cgtgaaaacggttttaccgagccggatccgcgtgacgatctgtcgggcatggacgtagca
cgtaagctcttgattctggcacgtgaagccggcatggaacttgagcttgacgatgttgag
gttgaacctgcgcttccgcctggctttgatcaatctggcgatgtcgaaagtttcatggca
cgtttgccgcaagccgatgactattttaaacaatggtcagaggaagccgccaaagaaggc
aaagtcttgcggtatattggtggtattgaagacggacgttgctttgtcaaaatccaagcc
gtatccgatgatgatcctatgaataaaatcaaagagggtgagaacgcgttggccttctat
agccgttattatcagccgattcctttggtgctgcgaggctatggcgcgggaaccgccgtg
accgcggctggggtgtttgcggacttaatgcgcaccctaggttggaagttaggagtctag
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