Skermanella cutis: IGS68_06875
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Entry
IGS68_06875 CDS
T07020
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
skt
Skermanella cutis
Pathway
skt00300
Lysine biosynthesis
skt00550
Peptidoglycan biosynthesis
skt01100
Metabolic pathways
skt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
skt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IGS68_06875
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IGS68_06875
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IGS68_06875
Enzymes [BR:
skt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IGS68_06875
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Hist_deacetyl
Motif
Other DBs
NCBI-ProteinID:
QQP90941
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Position
complement(1479344..1480855)
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AA seq
503 aa
AA seq
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MARPPVLWTAGDVAAATNGTLHGSADALDWQATGVSIDSRTIQPGDLFIALKGPNFDGHG
YVAQALAAGAAAALVSHRPDGVGPDAPLVMVEDTFAALQDLGSVARLRTGAKIVAVTGSV
GKTSTKEALGTCLSALAPTFATAGSLNNHWGVPLSLARMPPDCTYAVFELGMNHAGEIGP
LSRQVRPDVSVITTVEAVHLEHFPSVEAIADAKAEIFEGMAPNGAVVLNRDNPHYARLVA
AARTRGLSRILGFGKAEDASARLADCSIHATCSAVNAVIKGEALQYCLALPGRHHVMNSL
AVLLAVRALGGDVAAAARAMATLKPIKGRGARRRVRLAQGALTVIDESYNASPVSMEASF
QVLAKGDPGVGGRRIAVLGDMLELGERSPLLHAALAEPLKAASVDLVFCAGPDMKRLFDR
LPAALRGGWAPDSAALAPLVAGAVRAGDVLMVKGSAGSRMAAVVDAVAALDTGGDSDSNS
RTTPDETPGEIPDDRAQRAARQG
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
atggcacgcccccccgttctctggaccgccggcgacgtcgccgcggcgaccaacggcacc
ctgcacggctccgccgacgccctggactggcaggcgaccggcgtgtcgatcgacagccgc
acgatccagccgggcgatcttttcatcgctctgaagggtccgaacttcgacggccacgga
tacgtggcgcaggcgctggccgccggcgcggccgccgccctggtgtcgcaccggccggac
ggcgtcgggccggacgccccgctggtcatggtcgaggacaccttcgccgccctccaggac
ctgggctcggtggcgcggttgcgcaccggcgccaagatcgtcgcggtgaccgggtcggtc
ggcaagaccagcaccaaggaggcgctgggaacctgcctgtccgcgctggcgcccaccttc
gccacggcgggaagcctgaacaaccattggggcgtgccgctgagcctggcgcgcatgccg
ccggactgcacctacgccgtgttcgagctgggcatgaaccatgccggcgagatcggcccg
ctgtcccgccaggtccgccccgacgtctcggtgatcacgaccgtcgaggcggtccacctg
gagcatttcccgtcggtcgaggcgatcgccgacgccaaggcggagatcttcgaaggcatg
gcgccaaacggcgccgtggtgttgaaccgcgacaacccgcactatgcccggctggtcgcc
gccgcccgcacccgcgggctgtcgcgcatcctgggcttcggcaaggccgaggacgccagc
gcccggcttgccgactgctcgatccatgcgacctgcagcgcggtcaacgcggtgatcaag
ggcgaggcgctgcaatactgcctggcgctgcccggccgccaccacgtgatgaacagcctg
gccgtgctgctggcggtccgcgcgctgggcggcgacgtcgccgcggcggcgcgggccatg
gcgacgctgaagccgatcaagggacggggtgcccgccggcgcgtgcggctggcccagggc
gccctgaccgtgatcgacgagagctacaacgccagcccggtgtccatggaagcgagcttc
caggtgctggccaagggcgatccgggcgtcggcgggcggcgcatcgccgtgctgggcgac
atgctggagttgggcgagcggtcgcccctgctgcacgcggccctggccgagccgctgaag
gccgcctcggtggacctggtgttctgcgccggccccgacatgaagcgcctgttcgacagg
ctgccggccgccctgcgcggcggctgggccccggacagcgcggcgctggccccgctggtg
gccggggcggtgcgcgccggcgacgtcctgatggtcaaggggtcggccggcagccgcatg
gccgccgtggtcgacgcggtcgccgccctcgataccgggggcgattccgattcgaactcc
cgaacgactcccgacgaaactcccggcgaaattcccgacgacagggcgcaacgcgccgca
cggcagggctga
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