Streptomyces koyangensis: D0C37_25840
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Entry
D0C37_25840 CDS
T06436
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sky
Streptomyces koyangensis
Pathway
sky00300
Lysine biosynthesis
sky00550
Peptidoglycan biosynthesis
sky01100
Metabolic pathways
sky01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sky00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
D0C37_25840 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
D0C37_25840 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
D0C37_25840 (murF)
Enzymes [BR:
sky01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
D0C37_25840 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
AXQ57679
UniProt:
A0A385DI91
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All DBs
Position
5779972..5781396
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AA seq
474 aa
AA seq
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MIALSLAEISSIVGGQPADIPDLDAQVTGPVVIDSRLAAPGSLFAAFAGERADGHDYAAT
AVETGAVAVLATRPVGVPALVVDDVERALGALARAVVERLGTTVVALTGSAGKTSTKDLV
AQLLTRVAPTVWTPGSLNNEIGLPLTALRADTDTRHLVLEMGARGVGHIRYLTGLTPPRI
GVVLNVGSAHIGEFGGREQIALAKGELVESLPEDGVAILNADDSYVRDMASRTKARVVTF
GEAPEADIRAENVRLTENGRPAFTLHTPSGCGDVTMRLYGEHHVSNALAAAAVASELGMP
VDEIAQALSEAESLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALVAMGGARRGEG
GRTWAVLGQMAELGDEALTEHDAVGRLAVRLNVSKLVAVGGREAAWLQMGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVAAALLADGTGEGEVAAR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctggccgagatcagcagcatcgtcggcgggcaacccgccgacata
ccggacctggacgcccaggtcaccggaccggtcgtgatcgactcccggctcgccgcccca
ggcagcctcttcgccgcgttcgccggtgaacgggccgacggccacgactacgcggccacc
gccgtcgagaccggagccgtcgccgtcctcgcgacccggcccgtcggcgtgcccgccctc
gtcgtggacgacgtggagcgcgccctcggcgcgctcgcacgcgccgtcgtcgagcgcctg
ggcaccaccgtcgtcgccctcaccggctccgcgggcaagacctccaccaaggacctcgtc
gcgcagctcctgacgcgcgtcgcgcccacggtgtggacgcccggctccctcaacaacgag
atcgggctgccgctcaccgcgctgcgcgccgacacggacacccgccacctcgtcctggag
atgggggcgcgcggcgtcggtcacatccgctacctcaccggcctcaccccgccgcggatc
ggcgtcgtcctcaacgtcggcagcgcccacatcggcgagttcggcggccgcgagcagatc
gcgctggccaagggcgaactggtcgagtcccttcccgaggacggcgtcgcgatcctcaac
gcggacgacagttacgttcgtgacatggcgtcacgcaccaaggcgcgggtcgtcaccttc
ggcgaagcgcccgaagcggacatccgcgccgagaatgtccgtctcacggagaacggccgc
cccgccttcacgctgcacacaccctccgggtgcggcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgccgccgccgtcgcatcggaactgggcatgccc
gtggacgagatcgcccaagcgctctccgaggcggagtccctgtcccggtggcggatggag
gtcaccgagcgcccggacggtgtgacgatcgtcaacgacgcctacaacgcgaaccccgaa
tccatgcgggccgccctgcgcgcgctcgtggcgatgggcggcgcccgccgcggcgagggg
ggccgcacctgggcggtgctcggacagatggccgagctgggggacgaggcgctcaccgaa
cacgatgccgtcgggcggctcgccgtccggctcaacgtgagcaagctcgtggcagtcggc
ggcagggaagcggcctggctgcagatgggcgcatacaacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcggtcgacctgctgcgcagcgagctgcgccca
ggcgatgtcgtactcgtgaaggcttcccggtccgtgggactggagaaggtcgccgccgct
ctgctggcggacggtacgggcgagggtgaggtcgccgcccgatga
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