Sulfurimicrobium lacus skT11: SKTS_13110
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Entry
SKTS_13110 CDS
T06796
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
slac
Sulfurimicrobium lacus skT11
Pathway
slac00790
Folate biosynthesis
slac01100
Metabolic pathways
slac01240
Biosynthesis of cofactors
Module
slac_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
slac00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SKTS_13110 (folC)
Enzymes [BR:
slac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SKTS_13110 (folC)
6.3.2.17 tetrahydrofolate synthase
SKTS_13110 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BCB26425
UniProt:
A0A6F8VCE1
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Position
1332118..1333386
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AA seq
422 aa
AA seq
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MPESLGEWLAHLEQLHPSTIELGLARVATVKERLQFRPDFPILTVAGTNGKGSTCAMLEA
ILGAAGYRVGCYTSPHLLRYNERVRVAGYEVDDAALCRAFAAVEAARGDVSLTYFEFGTL
AAMWLFVQQQVEVAILEVGLGGRLDAVNVFDADCSVVTSVDIDHTDYLGDDRESIGREKA
GIFRATRPAICADHNPPHSLLQHAEGIGAELKLINRDFGAESQEGQWLFWSQAGWRMTLP
YPSLRGAYQLDNASACLAALEALKEKLPVTPENIRRGLLEASVPGRFQVLPGKPALILDV
AHNPHAARALASNLHQMWCGGRTIAVFAMLSDKDVAGVIAALREEVDLWLIAGIVHARGA
SAVELQARLSDVGIQAIQAFPDIAAAYHHACQIAGEDDRIAVFGSFHTVAEVMQSARNRK
PD
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgcctgagtctttaggggagtggctggctcatctggagcagttgcaccccagcaccatc
gaactgggcctggcgcgggtcgccaccgtcaaggaacgactgcagttcaggcccgatttc
cccatcctgaccgtcgctggcaccaacggcaaaggctcaacctgcgccatgctggaggcc
attctcggcgcggccggctaccgtgtcggctgttacacctcgcctcacttgctgcgctac
aacgagcgcgtgcgcgtcgccgggtatgaggtcgacgacgcggcactatgccgtgccttt
gccgccgtggaagctgcgcgcggcgatgtctccctgacttatttcgaattcggcacgctt
gcggcgatgtggctgttcgtccagcaacaggtcgaggtggcgattctggaggtgggcctg
ggtgggcgcctcgatgcggtgaatgtgttcgatgcggattgttcagtggtgaccagcgtg
gatatcgatcacacggattatctgggtgacgaccgcgaatccatcgggcgcgaaaaagcc
ggcatctttcgcgccaccaggccggccatatgtgctgatcataatccgccacacagcctg
ctgcagcacgccgagggcataggtgcagagttaaagctgatcaaccgcgatttcggtgcc
gaatcccaggaaggacaatggctgttctggagccaggccggctggcgcatgaccttgcct
tacccatcgctgcgtggcgcttaccagctcgacaatgccagcgcctgcctggcggcgctg
gaggcgctcaaggaaaaacttcccgtgacgccggaaaacatccgtcgtggcctgctggag
gcaagcgtgccgggccgctttcaggtgctgccaggcaagccggcgctgattcttgacgtg
gcgcacaatccccacgccgcgcgcgcgctggcttccaacttgcaccagatgtggtgtggc
ggcaggaccatcgcggtattcgccatgctgagtgacaaggatgtcgccggtgttatcgca
gcgctgcgcgaggaagtcgacctctggctgattgccggcatcgtccacgcgcgcggggct
agcgcggtcgagcttcaggcacgcctcagtgacgtgggcatccaagccatccaggcgttc
cccgatatcgctgccgcttaccaccatgcctgccaaatcgccggcgaagatgatagaatt
gcggtcttcggctcgttccatacggtagccgaggttatgcaaagcgcccgcaacaggaaa
cccgattga
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