Streptomyces lydicus 103: SL103_08835
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Entry
SL103_08835 CDS
T04699
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
slc
Streptomyces lydicus 103
Pathway
slc00300
Lysine biosynthesis
slc00550
Peptidoglycan biosynthesis
slc01100
Metabolic pathways
slc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SL103_08835
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SL103_08835
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SL103_08835
Enzymes [BR:
slc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SL103_08835
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
AOP46332
UniProt:
A0A1D7VHT9
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All DBs
Position
2053932..2055374
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AA seq
480 aa
AA seq
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MISLSLAEIASIVGGQQHDIPDADRQVTGPVVTDSRAVRPGGLFVAFAGERVDGHDFAAG
AVEAGAVAVLANRPVGVPAIVVHDVTTALGALARAVVERLGTTVVGLTGSAGKTSTKDLI
AQLLQRHGPTVWPEGNLNNEIGLPLTALRADATTRHLVLEMGARGIGHIRYLAALTPPRI
GVVLNVGSAHIGEFGGRAQIAEAKGELVEALPSAEEGGIAVLNADDPYVRAMAPRTKART
VLFGESEEAAVRAENVRLTDLGQPAFTLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMPVDEIATALSEAGTLSRWRMEVTERADGVTVVNDAYNANPESMRAALRALVAMGAAGK
AEGGRTWAVLGEMAELGEESLAEHDAVGRLVVRLNVSKLVAVGGREAAWLDMGAKNEGSW
GEESVHVSDARAAVDLLRSELRPGDVVLVKASRSVGLERVAAALLDDEGVTVAEGGAASR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtgatctccctgtccctcgccgagatcgcgagcatcgtcggcgggcagcagcacgacata
ccggacgccgaccgccaggtcaccgggcccgtcgtcaccgactcccgggcggtacggccc
ggcggcctgttcgtggcgttcgccggtgaacgcgtcgacggccacgacttcgcggccggc
gcggtcgaggccggtgccgtcgccgtgctcgccaaccgccccgtcggcgtacccgcgatc
gtggtccacgacgtcaccaccgcgctcggcgcgctcgccagggccgtcgtcgagcggctc
ggcaccaccgtcgtcggcctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctgctgcagcggcacgggccgaccgtctggccggagggcaacctcaacaacgag
atcgggctgccgctgaccgcgctgcgcgcggacgcgaccacccggcacctcgtgctggag
atgggcgcccgcggcatcggccacatccgctacctggccgccctgaccccgccgcggatc
ggtgtggtgctcaacgtcggcagcgcgcacatcggcgagttcggcggccgcgcgcagatc
gcggaggcaaagggcgaactcgtcgaggcgctgccgtcggccgaggagggcgggatcgcg
gtgctcaacgccgacgacccgtacgtccgcgccatggcgccgcgcaccaaggcccgcacc
gtcctgttcggtgagtccgaggaagcggccgtccgtgccgagaatgtccggctcaccgac
ctcggacagcccgctttcacgcttcacacaccctccgggtgcagtgatgtgaccatgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtagcccatgagttg
ggcatgcccgtcgacgagatcgccaccgcgctctccgaagccggcacgctctcccgctgg
cgtatggaggtcaccgagcgcgcggacggcgtgacggtcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgagcggcgctgcgtgcgctggtggcgatgggcgcggccggcaag
gccgagggcggtcgtacgtgggcggtgctcggtgagatggccgagctcggtgaggagtca
ctcgccgaacacgacgcggtcggacggctggtcgtccggctcaacgtcagcaagctcgtg
gcagtcggcggcagggaagcggcctggctcgacatgggcgccaagaacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcggtcgacctgttgcgcagcgag
ctgcgaccgggagacgtcgtgctggtcaaggcgtcccggtcggtggggctggagcgggtc
gccgcagcattgctggacgacgagggcgtgacggtcgctgagggtggagccgcgtcccga
tga
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