Streptomyces lydicus 103: SL103_23130
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Entry
SL103_23130 CDS
T04699
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
slc
Streptomyces lydicus 103
Pathway
slc00270
Cysteine and methionine metabolism
slc00480
Glutathione metabolism
slc01100
Metabolic pathways
slc01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slc00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SL103_23130
09106 Metabolism of other amino acids
00480 Glutathione metabolism
SL103_23130
Enzymes [BR:
slc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
SL103_23130
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
AOP48756
UniProt:
A0A1D7VPR4
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Position
5306757..5308037
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AA seq
426 aa
AA seq
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MPVRPAVTEAELEAHLHGICFKTGPPRRIGVEIEFLVHDARNPRCPVEPDRLHEAADALR
ALPLRSLLTFEPGGQLELSSQPAASLTECIESVTADLALVRPAMLARGLGMAGHGHNPWH
PPRRVLTDPRYNAMEAYFDRWGSAGRSMMCATASVQVCVDAGYDEPGPLGHGRRWLLAHL
LGAVLAAAFANSPTSEGCPTGYRTTRQLIWSQLDPDRTLAPPLGPDPRTAWARYVLDAPV
MCIRTDDGPWDAPEGLTFRDWVRTGVPRPPTQEDLDYHLTTLFPPVRPRGHLELRMIDAQ
SGDAGWVVPLAVTAALFDDPEAAERAYRTVKALAETAGPRPAPRNPLWRRAARGGLTDPE
LHAAAVACFAAAEEALPRLGASPEVRAAVAGFTERYVARGRCPADDHLDALYTAESDDLI
PGKDSQ
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgcccgtacggcctgcagtcacggaagcggaactcgaagcgcatctgcacggcatatgc
ttcaagacgggcccgccacgccgtatcggcgtcgagatcgaattcctggtccacgacgcg
cgcaacccccgatgtccggtcgaacccgaccggctgcacgaagccgccgacgcgctgcgc
gcactgcccctccgctccctgctgaccttcgaacccggcggtcagctggaactgagttcg
cagcccgccgcctccctgaccgagtgcatcgagtccgtgacggccgacctcgcactggta
cgccccgccatgctggcgcggggcctggggatggccggccacggtcacaacccgtggcac
ccaccacgccgggtactgaccgacccccgctacaacgccatggaggcgtacttcgaccgc
tggggctccgccgggcggtccatgatgtgcgccaccgcgtccgtgcaggtgtgcgtggac
gccgggtacgacgagccgggaccgctcgggcacggccggcgctggctgctggcccacctg
ctgggcgcggtgctggccgcggccttcgccaattcgccgaccagcgagggctgccccacc
ggctaccgcaccacccgccagctcatctggtcccagctcgacccggaccgtacgctcgcg
ccgccgctgggaccggacccgcgcaccgcgtgggcccgctacgtcctggacgcccccgtg
atgtgcatccgcaccgacgacgggccctgggacgcgccggaggggctcaccttccgggac
tgggtccgtaccggcgtgccccggccccccacccaggaggacctcgactaccacctcacc
acgctcttcccgcccgtacggccgcgcggccatctggagctgcgcatgatcgacgcccag
tccggcgacgccgggtgggtggtgccgctggccgtgaccgccgcgctgttcgacgacccg
gaggccgccgagcgcgcctaccgcacggtcaaggcgctggccgagacggcgggtccgcgg
ccggcgccgcgcaatccgctgtggcggcgggccgcccgcggggggctgaccgatccggag
ctgcacgccgcggcggtggcgtgtttcgccgcggccgaggaggcgctgccgcggctcggc
gcctccccggaggtgcgtgcggcggtcgcggggttcaccgagcgctatgtggcgcgcggc
cgctgtcccgcggacgaccacctcgatgccctgtacaccgcggagagcgacgacctcatt
cctgggaaggacagccagtga
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