Streptomyces lydicus 103: SL103_28045
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Entry
SL103_28045 CDS
T04699
Name
(GenBank) D-alanine--D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
slc
Streptomyces lydicus 103
Pathway
slc00470
D-Amino acid metabolism
slc00550
Peptidoglycan biosynthesis
slc01100
Metabolic pathways
slc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slc00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SL103_28045
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SL103_28045
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SL103_28045
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
slc01011
]
SL103_28045
Enzymes [BR:
slc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SL103_28045
Peptidoglycan biosynthesis and degradation proteins [BR:
slc01011
]
Precursor biosynthesis
Amino acid ligase
SL103_28045
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
AOP49587
UniProt:
A0A1D7VS76
LinkDB
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Position
complement(6487705..6488841)
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AA seq
378 aa
AA seq
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MSSQTPSHKPRVAVVFGGRSSEHAISVLTAGAVLRAIDREKYDVLPIGITTDGRWALTAD
DPDRMAITDRRLPSVAELAESAEGGVVLPVDPTNREVVYNEPGSVPKVLGEVDVVFPVLH
GPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKDYMKRVFTSFGLPVGPYEVIRPREWE
NDPAAARKKIVDFAGEHGWPLFVKPARAGSSMGISKVDDISGLDEAIEEARRHDPKILVE
SLLRGREIECGVLEFEDGPRASVPAEIPPVTAHDFYDFEAKYIDSATGIVPAPMTAEQTA
KVQELAVAAFEAASCEGLVRADFFLQDNGEFVINEINTLPGFTPISMYPRMWQESGVSYP
ELIDRLLRAALQRSTGLR
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgagcagccagaccccctcccacaagccccgcgtcgccgtcgtgttcggcggccgcagc
tccgagcacgccatctccgtactcaccgccggagccgtgctgcgcgccatcgaccgcgag
aagtacgacgtgctgcccatcggcatcaccacggacggccgctgggcgctgaccgccgac
gaccccgatcggatggccatcaccgaccggcggctgcccagcgtggccgagctcgccgag
tcggccgagggcggcgtggtgctcccggtcgacccgaccaaccgcgaggtcgtctacaac
gagccgggctcggtgcccaaggtgctgggcgaggtcgacgtggtcttccccgtcctgcac
ggcccctacggcgaggacggcaccctgcagggcctgctggagctctccggcgtgccctac
gtcggctcgggcgtgctcgcctccgccgtcggccaggacaaggactacatgaagcgggtg
ttcacctccttcgggctgcccgtcggcccgtacgaggtcatccgcccccgggagtgggag
aacgaccccgccgccgcccgcaagaagatcgtggacttcgccggtgagcacggctggccg
ctcttcgtgaagcccgcccgggccggctcctccatggggatcagcaaggtcgacgacatc
agcggcctggacgaggcgatcgaggaggcccgccggcacgaccccaagatcctcgtggag
tcgctgctgcgcggccgcgagatcgagtgcggggtgctggagttcgaggacggcccgcgg
gccagcgtgccggccgagatccccccggtcaccgcgcacgacttctacgacttcgaggcc
aagtacatcgactcggccaccgggatcgtccccgcgccgatgaccgccgagcagaccgcg
aaggtccaggaactggccgtcgccgccttcgaggccgcctcctgcgaggggctggtgcgc
gcggacttcttccttcaggacaacggcgagttcgtgatcaacgagatcaacaccctcccc
ggcttcacgcccatctcgatgtacccgcggatgtggcaggagagcggcgtgagctacccg
gagctgatcgaccggctcctccgggccgcgctgcagcgctcgacggggctgcgctag
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