Streptomyces lydicus A02: T261_4201
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Entry
T261_4201 CDS
T03756
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sld
Streptomyces lydicus A02
Pathway
sld00280
Valine, leucine and isoleucine degradation
sld00640
Propanoate metabolism
sld00785
Lipoic acid metabolism
sld01100
Metabolic pathways
sld01110
Biosynthesis of secondary metabolites
sld01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sld00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
T261_4201
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
T261_4201
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
T261_4201
Enzymes [BR:
sld01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
T261_4201
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AJT65855
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Position
4493101..4494270
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AA seq
389 aa
AA seq
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MLVMTVLEQPGSSRNKSSLPGPPPDWRPRVDPAPLLPDAEPYRLLGTPAARGLDADLLKR
LYAELVRGRRYNAQATALTRQGRLAVYPSSTGQEACQVAAALALEDRDWLFPSYRDTLAA
VARGLDPVQALTLLRGDWHTGYDPHRHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVAL
AMVGDGGTSEGDFHEALNFAAVWQAPAVFLVQNNGFAISVPLAKQSAAPSLAHKAVGYGM
PGRLVDGNDAPALHEVLTEAVQRARRGGGPTLIEAITYRIEAHTNADDATRYRTDAEVEA
WRAHDPIALLERELTARGLLTDEFAAATQDGAERLAADLRGRMNQDPVLDPMDLFTHVFA
EQTSQLRDQAAQLRAELDAEQTPAEEARP
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
gtgctcgtcatgacggtccttgagcagcccggcagcagcaggaacaagagctctctgccc
ggcccgccgcccgactggcggccgcgcgtcgatcccgcacctctcctgcccgatgccgag
ccgtaccgcctcctggggacgcccgccgcccgcgggctcgacgcggacctgctcaagcgg
ctctacgccgagctggtgcgcggccgccgctacaacgcccaggccacggccctgacccgg
caggggcggctcgcggtctatccgtcctccaccgggcaggaggcctgccaagtggccgcc
gcgctggccctggaggaccgcgactggctcttccccagctaccgcgacaccctcgccgcc
gtggcccgcggcctcgaccccgtacaggcgctgaccctgctgcgcggcgactggcacacc
ggctacgacccgcaccggcaccgcatcgcccccctgtgcaccccgctcgccacccagctc
ccgcatgccgtgggcctggcgcacgccgcccgcctcaagggcgacgacgtcgtggcgctg
gccatggtgggcgacggcggcaccagcgagggcgacttccacgaggcgctgaatttcgcg
gcggtctggcaggccccggccgtcttcctcgtccagaacaacggcttcgcgatctccgta
ccgctcgccaagcagtccgccgccccctccctggcccacaaggcggtcggttacggcatg
ccgggccgcctggtggacggcaacgacgcacccgccctgcacgaggtcctcaccgaggcc
gtacagcgcgcccgcaggggtggcggccccaccctgatcgaggccatcacctaccgcatc
gaggcccacaccaacgccgacgacgccacccgctaccgcaccgacgccgaggtcgaggca
tggcgggcgcacgacccgatagcccttctggagcgcgaactgaccgcccgcggactgctc
accgacgaattcgccgccgccacccaggacggcgccgagcgcctggcggccgacctgcgg
gggcggatgaaccaggacccggtgctcgacccgatggacctgttcacccacgtcttcgcc
gagcagaccagccaactacgtgaccaggccgcccagttgcgcgccgaactcgacgcagag
cagacccccgccgaggaggccaggccatga
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