Streptomyces lydicus A02: T261_6084
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Entry
T261_6084 CDS
T03756
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sld
Streptomyces lydicus A02
Pathway
sld00300
Lysine biosynthesis
sld00550
Peptidoglycan biosynthesis
sld01100
Metabolic pathways
sld01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sld00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
T261_6084
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
T261_6084
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
T261_6084
Enzymes [BR:
sld01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
T261_6084
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
AJT67700
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Position
6500930..6502354
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AA seq
474 aa
AA seq
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MISLSLAEIARITGGQMHDIPDAGAAVTGSVVMDSRQVRPGGLFVAFAGERADGHDFAAG
AVADGAVAVLAARPVGVPAIVVDDVVAALGALARAVVERLGTKVVALTGSAGKTSTKDLI
AQLLQRHGPTVWPEGNLNNEIGLPLTALRADASTRHLVLEMGARGVGHIRYLTGLTPPEI
GVVLNVGTAHIGEFGGREQIAVAKGELVEALPEHGVAVLNADDPYVSAMASRTKARTVLF
GEARNAEIRAENVRLTDLGQPAFTLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHELGMP
VDEIATALSEAGTLSRWRMEVTERADGVTVVNDAYNANPESMRAALRALVAMGAAAKAKG
GRTWAVLGEMAELGEDSLAEHDAVGRLVVRLNVSKLVAVGGREAAWLDMGAKNEGSWGEE
SVHVSDARAAVDLLRSELRPGDVVLVKASRSVGLERVAEALLDAAGAQGGAASR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatctccctgtccctcgccgagatcgccaggatcaccggcggacagatgcacgacata
ccggacgccggcgccgcggtcaccggatccgtcgtgatggattcccgccaggtccgcccc
ggcggtctgttcgtcgcgttcgccggtgaacgcgccgacggccacgacttcgccgcgggc
gcggtcgcggacggtgcggtggccgtgctggccgcccggcccgtcggcgtccccgcgatc
gtggtcgacgacgtggtcgccgccctcggcgcgctcgcccgcgccgtcgtcgagcgcctc
ggcaccaaggtcgtcgccctcaccggatcggccgggaagaccagcaccaaagatctcatc
gcccagctgctgcagcggcacgggccgaccgtctggccggaaggcaacctcaacaacgag
atcgggctgccgctgaccgcgctgcgcgccgacgcctcgacccgccatctcgtcctggag
atgggcgcccgcggcgtcggccacatccgctatctcaccgggctgaccccgccggagatc
ggcgtcgtgctcaacgtcggcaccgcccacatcggcgagttcggcggccgtgagcagatc
gccgtggccaagggcgaactcgtcgaggcgctcccggagcacggcgtcgcggtgctcaat
gcggacgatccgtacgtcagcgccatggcctcgcgtacgaaagcccgtacggtcctgttc
ggtgaggcccgaaatgccgagatccgtgccgagaatgtccggctcaccgatctcggacag
cccgctttcacgcttcacacaccctccgggtgcagtgatgtgaccatgcggctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttgggcatgccc
gtggacgagatcgccaccgcgctctccgaagccggcacgctctcccgttggcgcatggag
gtcaccgagcgcgcggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagcggcgctgcgagcgctggtcgcgatgggcgccgccgccaaggcgaagggc
ggtcgtacgtgggcggtgctcggtgagatggccgagctcggcgaggactcgctcgccgaa
cacgacgcggtcggacgcctggtcgtccggctcaacgtcagcaagctcgtggcggtcggc
ggcagggaagcggcctggctcgacatgggcgccaagaacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcgcgggcggcggtcgacctgttgcgcagcgagctgcgaccg
ggagacgtcgtgctggtgaaggcgtccaggtcggtgggtctggagcgggtggccgaggca
ttgctggacgccgcgggcgcccagggcggagccgcatcccgatga
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