Streptomyces leeuwenhoekii: cxmD
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Entry
cxmD CDS
T04414
Symbol
cxmD
Name
(GenBank) Polyketide synthase, type I, module 8
KO
K15672
rifamycin polyketide synthase modules 7 and 8
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle01051
Biosynthesis of ansamycins
sle01052
Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
cxmD (cxmD)
01051 Biosynthesis of ansamycins
cxmD (cxmD)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
sle01008
]
cxmD (cxmD)
Polyketide biosynthesis proteins [BR:
sle01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Rifamycin PKS
cxmD (cxmD)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
PKS_DH_N
SpnB_Rossmann
PP-binding
KAsynt_C_assoc
RhiE-like_linker
CurL-like_PKS_C
Thiolase_N
adh_short
Epimerase
Docking
Sacchrp_dh_NADP
GDP_Man_Dehyd
Glu_dehyd_C
Polysacc_synt_2
Shikimate_DH
Motif
Other DBs
NCBI-ProteinID:
CQR60494
UniProt:
A0A0F7VLL9
LinkDB
All DBs
Position
chromosome:complement(1242103..1247424)
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AA seq
1773 aa
AA seq
DB search
MADEVQLRDYLKRAIAEARDAHRRLREAEDRAREPIAVVAMACRYPGGVSSPDDLWRLVA
DGVDAVGGFPEDRGWDLDGFFDPDPDRPGTSYTRQGGFLRGAADFDAAFFGISPREALAM
DPQQRLLLETSWEAVERAGIDPLSLKSTDVGVFTGVAGQGYGAGAGVVTPESEGFAGTGA
APCVASGRVSYVLGLEGPAVTIDTACSSSLVAIHLAAQSLRQGECSMALAGGAMVMATPG
SFRSFSRQRGLAADGRCKAFSADADGMGLSEGVGVVLLERLSVARERGHRVLAVLRGSAV
NQDGASNGLTAPNGPSQQRVIRAALANAGLSATDVDVVEAHGTGTALGDPIEAQALLATY
GQGRAPGKPLWLGSLKSNIGHTQSAAGVGSVIKMVQALRHGVLPPTLHAQEPTPQVDWSA
GAVELLTEARAWPREDRPRRAGVSGFGISGTNAHLILEEAPEEPGTEEPQEYAGVVPWVV
SARSAASLAGQAARLAAFLEDSGDMPPAAVAEALVSGRAEMSERAVVVADSAEEALGGLR
ALARGVTAPAGVVTGSTGPRGKLVWVFPGQGAQWAGMGRELLDASPVFAERIAECAAALE
PWIDWSLTEVLRGEADPELLDRVDVLQPASFAVMVGLAAVWSSVGVVPDAVVGHSQGEIA
AACVAGALSLEDAARVVALRSQAIAAKLSGRGGMASVALSEADALARLAPWAGRVEVAAV
NSPSSVVVAGDAQALDEALEALSGSGVRVRRVAVDYASHTRHVEDIRDTLAEALKVTAEA
PVVPFFSTVTGAWIEDAGVLDGGYWYRNLRAQVGFGPAVAQLIAQGHGVFVEVSAHPVLV
QPITEIADAGDADVLVTGSLRRDDGGLRRLLASVAECYVRGVTVDWTGVLPPVSARVELP
TYAFDHRHYWLQPVDTQTDAASLGLAGADHPMLGAVVPLPQSDGLVFTSRLSLRSYPWLA
EHTVDDVVVVPGGALVELAVRAGDEAGCSVLDELVIETPLVVPDDGGVCVQVALGGPAED
GSRSVEVFSLGEGEVWRRHARGVLSAAEPVGRGSGFDFGVWPPPGAQSMSGGHVWRRGEE
VFAEVVLPEGVDAGGFGVHPALLEAAVLSGGPDVGLPLEWRGLVVHAVGASVLRVRLVVS
AAGGVSVEAADEAGGLVVSAESVVFGPVSVERPGLKDALFRVEWVELPAVAGEPSPSWSP
VVSAGELPSGMAVLEADGGQESPLSLTSRVLAVVQAWLAGPALEDARLVVVTRGAVAAGD
GAVTDAAGAAVWGLVRAAQAENPDRIVLLDLDADRSVDDVLGSVLACAEPQVAVRGTTLC
VPRLARAEFSEPVGVFRPDGTVLVSGAGALGALAARHLVARHGVRRLVLASRRGQGAEGV
PELVDELTAHGATVEVVACDVSDRDQVAALLEAHRPIAVVHTAGVLDDGVIGALSPDRLA
TVFAPKVDAVRHLDELTRTMGLDLDTFVVFSSASGVFGSAGQGNYAAANAFLDALMVRRR
AEGLPGLSLAWGLWEQATGMTAHLGGTDQARMSRGGVLALTAAEGMELFDAAVGSGQALL
VPVKLDLRGTSEQVPYLLRGLVRPGWRRQAQGTAAGGEGDVGGLVRRLAGLGASEQEEVL
LGLVRTQTAVVLGHDGPEAVRAETAFKEAGFDSLTSVELRNRLREATGLKLPATLVFDYP
TPAVLARHLRDQLGHGDDAVSLVTAKLEDLESLISGLRLDAATQSTVTLRLQGLVAKCNG
ILEPAGVSTVANQLEGASADEVLDFIDEELGLI
NT seq
5322 nt
NT seq
+upstream
nt +downstream
nt
gtggctgacgaggtacaactccgcgactacctcaagcgggccatcgccgaggcccgcgac
gcccaccggcggctgcgcgaggccgaggaccgggcgcgggagcccatcgccgtcgtcgcc
atggcctgccgctacccgggcggcgtctcctcacccgacgacctgtggcggctggtcgcc
gacggcgtcgacgccgtcggcggcttccccgaggaccgcggctgggacctggacggcttc
ttcgacccggaccccgaccgccccggcacctcgtacacccggcagggcggattcctgcgc
ggggccgccgacttcgacgccgcgttcttcgggatctccccgcgcgaggccctcgccatg
gacccgcagcagcggctgctcctggagacctcctgggaagcggtggaacgcgccgggatc
gacccgctctccctcaagagcaccgacgtcggcgtgttcaccggcgtcgccggacagggc
tacggcgccggagccggagtcgtcacccccgagtcggaaggcttcgccggcaccggagcg
gccccctgtgtggcatccggccgcgtctcttacgtcctcgggctggaaggcccggcggtg
accatcgacacggcgtgttcctcgtccctggtggccatccacctggccgcgcagtcgctg
cgccagggcgagtgctcgatggccctggccgggggcgcgatggtgatggcgacaccgggt
tccttccgctccttctcccggcagcggggactggcagcggacggccgctgcaaggcgttc
tccgccgacgcggacggcatgggcctgtccgagggcgtgggtgtcgtcctgctggagcgg
ctgtcggtggcgcgggagcgcgggcaccgggtgctggcggtgctgcgcggcagcgcggtc
aaccaggacggcgcgtcgaacgggctcacggcccccaacggaccctcgcagcagcgggtg
atccgcgccgcgctcgccaacgccgggctgtcggcgacggacgtggacgtggtggaggcc
cacggcaccggcacggccctcggcgacccgatcgaggcccaggcgctcctggcgacctac
gggcagggccgtgcgccggggaagccgctgtggctgggctcgctgaagtccaacatcggc
cacactcagtcggcggcgggcgtgggcagcgtgatcaagatggtccaggcgctccggcac
ggagtgctgccgccgaccctgcacgcacaggagccgacgccccaggtggactggtcggcg
ggcgcggtcgaactgctcaccgaggcccgcgcatggccgcgcgaggaccgaccgcgccgc
gccggggtctccggattcggcatcagcgggaccaacgcccatctgatcctggaggaggca
cccgaggagccggggaccgaggagccgcaggagtacgcgggtgtggtgccgtgggtggtg
tcggcgcggtcggcggcgtcgctggccgggcaggcggcgcggctggccgccttcctggag
gactcgggggacatgccgccggccgcggtggcggaagcgctggtctccggccgggccgag
atgagcgagcgggccgtggtggtggccgactcggcggaggaggcgctgggcggactgcgg
gcgctggcacggggagtgacggcgccggcgggcgtggtgacgggcagcacgggcccacgg
ggcaagctggtgtgggtgttccccggtcagggcgcgcagtgggcgggcatgggccgtgaa
ctgctggacgcctccccggtgttcgcggagcggatcgcggagtgcgcggcggcgctggag
ccgtggatcgactggtccctgacggaggtgctgcggggggaggcggacccggagctgctg
gaccgggtggatgtgctccagcccgcgagtttcgcggtgatggtggggctggcggcggtg
tggtcgtcggtgggtgtggtgccggatgcggtggtgggccactcgcagggcgagatcgca
gccgcgtgtgtggcgggcgcgctgtcgctggaggacgcggcccgcgtcgtggcgctgcgc
agccaggccatcgccgcgaagttgtcggggcggggcggtatggcgtcggtggccttgtcc
gaggcggacgcccttgcccgcctggctccgtgggcgggccgggtggaggtggccgccgtc
aacagcccgtcgtcggtggtggtcgcgggggacgcgcaggcgctggacgaggcgttggag
gcgctgtccggcagcggggtccgggtgcggcgggtcgcggtggactacgcctcgcacacc
cggcatgtggaggacatccgcgacacgctcgccgaggcgctgaaggtgaccgccgaggca
ccggtcgtgcccttcttctccaccgtcaccggcgcgtggatcgaggacgccggggtgctg
gacggcggctactggtaccgcaacctgcgcgcacaggtgggcttcggccccgccgtcgcc
cagctcatcgcgcagggccacggcgtgttcgtggaggtcagcgcccacccggtgctggtc
cagccgatcaccgagatcgccgatgccggcgacgccgatgtgctggtgaccgggtcactg
cgccgtgacgacggcggactgcggcggctcctcgcctccgtggccgagtgctacgtccgg
ggtgtcaccgtcgactggaccggcgtcctgccgcccgtctccgcacgggtggagctgccg
acgtacgccttcgaccaccggcactactggctccagccggtggacacccagaccgatgcc
gcgtcgctggggctggcgggcgcggatcacccgatgctgggcgcggtggtgccgttgccg
cagtcggacgggctggtgttcacctcgcggctgtcgctgcggtcgtatccgtggctggcc
gagcacaccgtcgacgacgtggtggtcgtcccgggcggcgcgctggtggagctggcggtg
cgggccggggacgaggccgggtgctcggtgctggacgagctggtgatcgagacgccgttg
gtcgtgcccgacgacggtggtgtctgcgtgcaggtcgcgctgggtggtcccgcggaggac
ggctcacgctcggtggaggtgttctcgctgggcgagggtgaggtgtggaggcggcatgcc
aggggtgtgctgtcggctgccgaaccggtcggccgggggtcgggcttcgatttcggggtg
tggccgccgccgggggcgcagagcatgtctggggggcatgtgtggcggcgtggtgaggag
gtgttcgccgaggtcgtcctgccggagggtgtggacgcgggtggcttcggggtgcatccg
gcgttgctggaggctgcggtgctgagcggcgggccggacgtggggctgccgttggagtgg
cgtgggctggtcgtgcatgcggtgggtgcgtcggtgctgcgggtgcggttggtggtgtcg
gcggctggtggtgtgtcggtggaggcggcggacgaggccggtggcctggtggtgtcggcc
gagtcggtggtgttcgggccggtgtccgtggagcggccggggctcaaggatgcgctgttc
cgggtggagtgggttgagctgcctgcggttgcgggggagccgtccccgtcgtggagtccc
gtggtctcggccggggagctgccttcgggtatggcggtgttggaggccgatggcggtcag
gagtcgccgctgtcgttgacctcacgggtcctggctgtggtgcaggcatggctggccggt
cccgcgctggaggatgcccggctggtcgtggtcacccgaggtgcggtggccgccggggac
ggggcggtgacggacgctgcgggtgcggcggtgtggggtctggtgcgggccgctcaggcg
gagaacccggaccggatcgtgctgctggatctcgacgccgaccgcagtgtggacgacgtg
ctgggctcggtactggcgtgcgccgagcctcaggtcgcggtccggggcaccacgctctgc
gtgccccggctggcccgtgccgagttctccgaaccggtcggcgtcttccgtccggacggg
accgtcctggtctcgggtgcgggtgcgctcggtgccttggcggctcggcacctggtcgcc
cggcacggtgtacggcgcctggtgctcgccagcaggcgaggtcaaggtgccgagggcgtc
ccggagctggtcgatgaactgaccgcgcacggcgccacggtggaggtcgtcgcctgtgac
gtctccgaccgcgaccaggtggcggcactgctggaggcgcaccgcccgatcgccgtggtg
cacacggccggtgtgctggacgacggtgtgatcggggcgttgtcgccggaccggctggcc
acggtcttcgcgccgaaggtggacgccgtacggcacctcgacgagctgacccgcacgatg
ggcctggatctcgacaccttcgtggtgttctcgtcggcgtcgggtgtgttcggttcggcc
ggtcagggcaactacgcggcggcgaacgcctttctggacgcgttgatggtccggcgacgg
gccgaggggctgcccgggctgtcgctggcgtgggggctgtgggagcaggccacggggatg
acggcgcacctgggcgggaccgaccaggcgcgtatgagccggggtggtgtgctggcgttg
acggcggcggagggcatggagctgttcgacgcggcggtcgggtccgggcaggcgctgctg
gtgccggtgaagctggacctccgggggacgagcgagcaagtgccgtatctgttgcggggg
ctggtgcgcccagggtggcggcggcaggctcagggcacggcggcgggcggtgaaggcgac
gtcgggggcctggtccgccggttggcgggactgggcgcgtccgagcaggaggaggtgctg
ctcggtctggtccggacgcagacggcggtggtgctcgggcacgacgggccggaagccgtg
cgggcggaaacggcgttcaaggaggccgggttcgactcgctgacctcggtcgagttgcgc
aaccggctgcgggaggcgaccgggctgaagctgcccgccacgctcgtcttcgactacccc
accccggcagtgctcgcccgtcacctgcgcgaccagctcgggcacggtgacgacgccgtc
tccctcgtgaccgcgaagctggaggacctcgagtcgctgatcagcggtctgcgtctcgac
gcggcgacgcagtccacggtcacgctgcgccttcagggcctggtggccaagtgcaacggg
atcctggagcccgcgggcgtctccacggtcgccaaccagctggaaggcgcgtccgccgac
gaggtcctcgacttcatcgacgaagaactcggcctcatctga
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