Streptomyces leeuwenhoekii: sle_21250
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Entry
sle_21250 CDS
T04414
Symbol
sle_21250
Name
(GenBank) Uncharacterized AIPM/Hcit synthase family transferase SCO5529
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00290
Valine, leucine and isoleucine biosynthesis
sle00620
Pyruvate metabolism
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
sle01210
2-Oxocarboxylic acid metabolism
sle01230
Biosynthesis of amino acids
Module
sle_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
sle_21250 (sle_21250)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
sle_21250 (sle_21250)
Enzymes [BR:
sle01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
sle_21250 (sle_21250)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
CQR61586
UniProt:
A0A0F7VXF5
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Position
chromosome:complement(2613752..2615356)
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AA seq
534 aa
AA seq
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MTATSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGANPRD
TEFFARARQEIEFQHAQLVAFGSTRRAGTTAAEDPQVKALLESGAPVITLVAKSHDRHVE
LALRTTLDENLEMVRDTVSFLRSQGRRVFVDCEHFFDGYRANPEYAKAVVRTASEAGADV
VILCDTNGGMLPAQIHAVVSTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTA
NGYGERVGNANLFPVVAALELKYGKKVLPEGRLRETTRISHAIAEVVNLTPSTHQPYVGV
SAFAHKAGLHASAIKVDPDLYQHIDPEQVGNTMRMLVSDMAGRASIELKGKELGIDLGGD
RELVGRVVERVKERELKGYTYEAADASFELLLRTEAEGRPLEYFEVESWRAIVEDRPDGT
HANEATVKLWAKGERIVATAEGNGPVNALDRALRVALEKIYPQLARLELVDYKVRILEGK
HGTQSTTRVLISTSDGQGEWSTVGVGDNVIAASWQALEDAYTYGLLRAGVAPAR
NT seq
1605 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcaaccagcgagctcgacgattcgttccacgtcttcgacaccacgctgcgcgac
ggcgcgcagcgcgagggcatcaacctcaccgtcgcggacaagctggccatcgcgcggcac
ctggacgacttcggcgtgggcttcatcgagggcggctggcccggcgccaacccgcgggac
acggagttcttcgcccgtgcccggcaggagatcgagttccagcacgcccagctcgtggcc
ttcggctccacccgccgcgccggcaccaccgccgccgaggacccgcaggtcaaggccctg
ctggagtccggcgccccggtgatcacactggtcgccaagtcccacgaccggcacgtcgag
ctggcgctgcgcaccaccctggacgagaacctggagatggtccgcgacaccgtctccttc
ctgcggtcgcagggccgccgcgtcttcgtcgactgcgagcacttcttcgacggctaccgc
gccaaccccgagtacgccaaggcggtcgtccgcacggcctcggaggcgggcgcggacgtc
gtcatcctgtgcgacaccaacggcggcatgctcccggcgcagatccacgccgtggtctcc
acggtcctcgccgacaccggtgcccgcctcggcatccacgcccaggacgacaccgggtgc
gccgtcgccaacaccctcgccgcggtcgacgcgggcgccacccacgtccagtgcacggcg
aacggctacggcgagcgcgtcggcaacgccaacctcttcccggtggtggccgcgctggag
ctgaagtacggcaagaaggtcctgcccgaggggcggctgcgggagacgacccgcatctcg
cacgccatcgccgaggtcgtcaacctcaccccctccacccaccagccctacgtgggtgtc
tccgccttcgcccacaaggccggcctgcacgcctccgccatcaaggtggaccccgacctg
taccagcacatcgaccccgagcaggtcggcaacaccatgcggatgctcgtctccgacatg
gccggccgcgcctcgatcgagctgaagggcaaggagctcggcatcgacctcggcggcgac
cgggagctggtcggccgggtcgtcgagcgggtcaaggagcgcgaactcaagggctacacg
tacgaggcggccgacgccagcttcgaactcctgctgcgcaccgaggccgagggccggccg
ctggagtacttcgaggtggagtcctggcgcgcgatcgtcgaggaccgccccgacggcacc
cacgccaacgaggccaccgtcaagctgtgggccaagggggagcgcatcgtcgccacggcc
gagggcaacggcccggtcaacgccctggaccgcgccctgcgcgtcgccctggagaagatc
tacccgcagctcgcccggctggagctggtcgactacaaggtccgcatcctggagggcaag
cacggtacccagtcgacgacccgggtcctcatctccacctccgacggacagggggagtgg
tccacggtgggtgtcggggacaacgtcatcgccgcctcctggcaggccctggaggacgcc
tacacctacgggctgctgcgggccggggtggcgccggcgcggtag
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