Streptomyces leeuwenhoekii: sle_28620
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Entry
sle_28620 CDS
T04414
Symbol
sle_28620
Name
(GenBank) Bifunctional purine biosynthesis protein purH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00230
Purine metabolism
sle00670
One carbon pool by folate
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
Module
sle_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
sle_28620 (sle_28620)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
sle_28620 (sle_28620)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sle04147
]
sle_28620 (sle_28620)
Enzymes [BR:
sle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
sle_28620 (sle_28620)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
sle_28620 (sle_28620)
Exosome [BR:
sle04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
sle_28620 (sle_28620)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
CQR62323
UniProt:
A0A0F7VV61
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All DBs
Position
chromosome:complement(3444601..3446163)
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AA seq
520 aa
AA seq
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MTADSNKRPIRRALVSVYDKTGLEELARGLHEAGVELVSTGSTAARIAAAGVPVTKVEEL
TGFPECLDGRVKTLHPKVHAGILADLRLDTHRQQLDELGVAPFDLVVVNLYPFRETVASG
ATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYGDVLAAARDGGFDLAARKRLAAE
AFRHTAAYDVAVASWFASEYAPADDSSFPDFLGATWDRAHTLRYGENPHQPAALYVSGTG
GLAEAEQLHGKEMSYNNYTDTDAARRAAYDHAEPCVAIIKHANPCGIAIGADVAEAHRKA
HACDPLSAFGGVIAVNRPVSKEMAEQVAEIFTEVIVAPGYEDGALEILTKKKNIRVLRAP
EAPAAPVEIKPIDGGALLQVADRLQAEGDDPATWTLASGEALSEAELAELAFAWRACRAV
KSNAILLAKDGASVGVGMGQVNRVDSCRLAVERAGEERARGAFAASDAFFPFPDGPEILI
EAGVRAIVQPGGSIRDEQVVEAAKKAGVTMYFTGTRHFFH
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccgacagcaacaagcggccgattcgccgggcgctcgtcagcgtctacgacaag
accgggctggaagagctcgcgcgcggcctgcacgaggccggcgtcgagctggtctccacc
ggctccaccgccgcccggatcgccgccgccggcgtccccgtcaccaaggtcgaggagctc
accggcttccccgagtgcctcgacggccgcgtcaagaccctgcaccccaaggtgcacgcg
ggcatcctcgccgacctgcgcctggacacccaccggcagcagctcgacgagctcggcgtc
gcgccgttcgacctggtcgtggtcaacctctacccgttccgcgagacggtcgcctcgggc
gccacccccgacgagtgcgtggagcagatcgacatcggcggcccctccatggtccgcgcc
gccgccaagaaccacccctccgtcgccgtggtcaccagccccgcccggtacggggacgtc
ctcgccgcggccagggacggcggcttcgacctggccgcccgcaagcgcctggccgccgag
gcgttccggcacacggccgcctacgacgtggcggtcgcctcctggttcgcctccgagtac
gccccggccgacgactcgtccttccccgacttcctgggcgccacctgggaccgcgcgcac
accctgcgctacggcgagaacccgcaccagcccgccgccctgtacgtctccggcaccggc
ggcctcgccgaggccgagcagctccacggcaaggagatgtcgtacaacaactacacggac
acggacgccgcccgccgtgccgcgtacgaccacgccgagccctgcgtggcgatcatcaag
cacgccaacccgtgcggcatcgcgatcggcgcggacgtcgccgaggcgcaccgcaaggcg
cacgcctgcgacccgctgtccgcgttcggcggcgtgatcgccgtcaaccggccggtcagc
aaggagatggccgagcaggtcgcggagatcttcaccgaggtcatcgtcgcgcccggctac
gaggacggcgcgctggagatcctcaccaagaagaagaacatccgcgtgctgcgtgccccc
gaggcgcccgccgcgcccgtggagatcaagccgatcgacggcggcgccctcctccaggtc
gccgaccgcctccaggccgagggcgacgacccggccacctggaccctcgccagcggcgag
gccctgtccgaggcggagctggccgagctggcgttcgcctggcgggcctgccgcgcggtg
aagtccaacgcgatcctgctggcgaaggacggcgcctcggtcggcgtcggcatgggccag
gtcaaccgggtcgactcctgccgcctcgccgtcgagcgggccggcgaggagcgggcgcgc
ggcgcgttcgcggcctcggacgccttcttcccgttcccggacggccccgagatcctgatc
gaggccggggtccgggccatcgtccagcccggcggctcgatccgcgacgagcaggtcgtc
gaggccgcgaagaaggccggcgtgacgatgtacttcaccggcacccgccacttcttccac
tga
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