Streptomyces leeuwenhoekii: sle_35230
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Entry
sle_35230 CDS
T04414
Symbol
sle_35230
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00280
Valine, leucine and isoleucine degradation
sle00640
Propanoate metabolism
sle00785
Lipoic acid metabolism
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
sle01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
sle_35230 (sle_35230)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
sle_35230 (sle_35230)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
sle_35230 (sle_35230)
Enzymes [BR:
sle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
sle_35230 (sle_35230)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
CQR62984
UniProt:
A0A0F7VR65
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Position
chromosome:complement(4174620..4175843)
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AA seq
407 aa
AA seq
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MTVESTAARKPRRSAGSKAGTTGTKAAGTTGTKRTTRTAAKKTAEKSTEPELVQLLTPEG
ERVENAEYDAYVAGVTPDELRGLYRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQI
GSGRATREDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNNGGWDPNGNNFHLYTIVIGS
QALHATGYAMGIAKDGADSAVIAYFGDGASSQGDVSEAFNFAAVYNAPVVFFCQNNQWAI
SESNEKQTRVPLYQRAQGFGFPGVRVDGNDVLATLAVTRWALERARRGEGPALIEAWTYR
MGAHTTSDDPSRYRHDDERAAWEAKDPILRLRRHLEAAHHADESFFAELEAESEALGKRV
REAVRAMRDPDRFAIFENVYADGHALVDEERAQFAAYQASFADAEGV
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgacgcagcgccggaagcaaggccgga
acgaccggtacgaaggcggccggcaccaccggcaccaagcgcaccacccgcaccgctgcc
aagaaaaccgccgagaaaagcactgagccggaactcgtccagttgctgacgcccgagggc
gagcgcgtcgagaatgccgagtacgacgcgtacgtcgccggcgtcacccccgacgagctg
cgcggcctgtaccgcgacatggtgctcacccggcgcttcgacgccgaggccaccgccctg
cagcgccagggcgagctcggcctgtgggcctccctgctggggcaggaggccgcccagatc
ggctccggccgcgccacccgggaggacgactacgtcttccccacctaccgcgagcacggc
gtcgcctggtgccgcggggtcgacccgaccaacctgctcggcatgttccgcggcgtgaac
aacggcggctgggaccccaacggaaacaacttccacctctacacgatcgtcatcggctcg
caggcgctgcacgccaccggctacgccatgggcatcgccaaggacggcgcggactcggcc
gtgatcgcctacttcggcgacggcgcctccagccagggcgacgtgagcgaggcgttcaac
ttcgccgcggtctacaacgctccggtggtcttcttctgccagaacaaccagtgggcgatc
tcggagtccaacgagaagcagacccgggtgccgctgtaccagcgcgcgcagggcttcggc
ttccctggcgtccgcgtcgacggcaacgacgtcctggccacgctcgccgtcacccgctgg
gcgctggagcgggcccggcgcggcgagggcccggcgctgatcgaggcgtggacgtaccgc
atgggcgcccacaccacgtccgacgaccccagccgctaccgccacgacgacgagcgggcc
gcctgggaggcgaaggacccgatcctgcgcctgcgccgccacctggaagccgcccaccac
gcggacgagagcttcttcgcggaactggaagccgagagcgaggcgttgggcaagcgggtg
cgcgaagcggtccgcgccatgcgggacccggaccggttcgccatcttcgagaacgtgtac
gcggacgggcacgcgctcgtcgacgaggagcgggcgcagttcgccgcctaccaggcgtcc
ttcgccgacgcagagggggtctga
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