Streptomyces leeuwenhoekii: sle_55540
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Entry
sle_55540 CDS
T04414
Symbol
sle_55540
Name
(GenBank) Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]
KO
K00595
precorrin-6B C5,15-methyltransferase / cobalt-precorrin-6B C5,C15-methyltransferase [EC:
2.1.1.132
2.1.1.289
2.1.1.196
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00860
Porphyrin metabolism
sle01100
Metabolic pathways
sle01240
Biosynthesis of cofactors
Module
sle_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
sle_55540 (sle_55540)
Enzymes [BR:
sle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.132 precorrin-6B C5,15-methyltransferase (decarboxylating)
sle_55540 (sle_55540)
2.1.1.196 cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]
sle_55540 (sle_55540)
2.1.1.289 cobalt-precorrin-7 (C5)-methyltransferase
sle_55540 (sle_55540)
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Gene cluster
GFIT
Motif
Pfam:
TP_methylase
Methyltransf_25
Methyltransf_11
Methyltransf_31
Methyltransf_12
PrmA
Methyltransf_23
LPD22
MTS
Cons_hypoth95
Methyltransf_15
CMAS
ADH_zinc_N
Motif
Other DBs
NCBI-ProteinID:
CQR65011
UniProt:
A0A0F7W6T9
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Position
chromosome:6499807..6501042
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AA seq
411 aa
AA seq
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MADRVTVIGWDGSPLTAAARAALGAATLVAGAAHHLALPEVPPAAERIRLGSVALAARRI
AAHRGTAVVLADGDPGFFGVVRTLRAPEFGLEVEVVPAVSSVATAFARAGMPWDDAHVVV
AHPRTLRRAVNVCRAHTKVAVLTAPGAGPAELGLLLDDVHRTFVICEELGTAHERVTVVT
SDKAADHTWRDPNVVIVIGGPSGPGVTADGGGWIAGRDPAAGPRGWSLPAEAYGGGLGEG
ETDLLRTAQLARLGPRLGDLVWDIGCGSGAFATEAARGGAAVIAVDRDPDACARTEATAR
RFGVQLQTVCGTAPHVLEDLPEPDVVRVGGGGAAVVSAVADRRPQRIVTHAATRDAAELV
GRDLTEHGYVVECALLQSVALDTRAWTEKERSVAFLLSGELPRREGGAPGR
NT seq
1236 nt
NT seq
+upstream
nt +downstream
nt
atggccgaccgggtcacggtgatcggctgggacggttcgccgctgaccgccgcggcacgc
gccgcgctgggcgccgccaccctcgtggccggtgccgcccaccacctcgcgctgccggag
gtaccgcccgccgccgaacgcatccgcctcggcagcgtcgccctcgccgcccgccgcatc
gccgcccaccgcggcacggcggtcgtgctcgccgacggcgaccccggcttcttcggtgtc
gtacggaccctgcgcgcgccggagttcggcctggaggtcgaggtcgtcccggccgtctcc
tccgtggccaccgccttcgcccgggccggcatgccctgggacgacgcccatgtcgtcgtc
gcccacccccgcaccctgcgccgcgcggtcaacgtctgccgggcccacaccaaggtggcg
gtcctcaccgctccgggcgccggccccgccgaactcggcctgctgctggacgacgtccac
cgcaccttcgtcatctgcgaggaactcggcaccgcccacgagcgggtcaccgtcgtcacc
tccgacaaggccgccgaccacacctggcgcgaccccaacgtcgtcatcgtcatcggcgga
cccagcgggcccggtgtcacggcggacggcgggggctggatcgccggccgcgacccggcc
gccgggccccgcggctggtcgctgcccgccgaagcctacggcggcggcctcggcgagggc
gagaccgacctgctgcgcacggcccagctcgcccggctcggaccgcgcctcggggacctc
gtgtgggacatcggctgcggcagcggcgcgttcgccaccgaagccgcccgcggcggcgcc
gccgtcatcgccgtcgaccgcgacccggacgcctgcgcccgcaccgaggccaccgcccgc
cgcttcggcgtccagctccagaccgtctgcggcaccgctccgcacgtcctggaggacctc
cccgagcccgacgtcgtccgcgtcggcggcgggggagcggccgtggtctcggcggtcgcc
gaccgccgcccgcagcgcatcgtcacgcacgccgccacccgcgacgccgccgaactcgtc
ggccgcgacctgacggagcacggctacgtcgtcgagtgcgccctgctccagtccgtcgcc
ctcgacacccgggcctggacggagaaggaacgcagcgtcgccttcctgctcagcggagag
ctgccgcggcgcgagggcggtgcccccgggcgctga
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