Streptomyces liliifuscus: JEQ17_30775
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Entry
JEQ17_30775 CDS
T08169
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
slf
Streptomyces liliifuscus
Pathway
slf00790
Folate biosynthesis
slf01100
Metabolic pathways
slf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
JEQ17_30775
Enzymes [BR:
slf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
JEQ17_30775
6.3.2.17 tetrahydrofolate synthase
JEQ17_30775
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QQM43350
UniProt:
A0A7T7RE70
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Position
7140117..7141631
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AA seq
504 aa
AA seq
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MSEFPHDSSESDPADPFDEIVEAETGRDPDLAVIEAGSRTLRTQGGPPESDIPTRPADQE
TDKALREVEAELATRWGETKLEPSVSRISALMDVLGEPQRAYPSIHITGTNGKTSTARMI
EALLGAFDLRTGRYTSPHVQSITERISLDGAAISADRFVETYRDIQPYVEMVDSQQEFRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGTTP
GEIAKEKAGIVKQDATVILAQQPVDAAQVMLKKAVEVDATVAREGLEFGVVSRQVAVGGQ
LLTLRGLGGEYDEVYIPLHGAYQAHNAAVALAAVEAFFGVGSQRPEPLDIDTVRKAFAAV
SSPGRLEIVRRSPTVVLDAAHNPAGARATAEGVREVFDFSRLIGVVGSSGDKNVRGLLEA
FEPIFTEVVVTQNSSHRAMDVDSLAAIAVEVFGDDRVQVESRLDDALEAAITLAEEEAEY
AGAGVLVTGSVITVGEARLLLGRG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagttcccgcacgacagcagtgagtcagacccggccgacccgttcgacgagatc
gtcgaggcggagaccgggcgtgatcccgatctcgccgtgatcgaggccggcagccgtacc
ctgcgcacgcagggcgggccgccggagtccgacattcccacgcgcccggccgaccaggag
accgacaaggcgctccgtgaggtcgaggccgagctcgcgacgcgctggggcgagaccaag
ctggagccgtccgtgagccgcatctccgcgctcatggacgtgctgggggagccgcagcgc
gcgtatccctccatccacatcacggggacgaacggcaagacgtcgaccgcccgcatgatc
gaggccctcctcggcgccttcgacctgcgcaccgggcggtacacctcgccgcacgtccag
tcgatcaccgagcgcatcagcctggacggcgccgcgatctccgccgaccggttcgtggag
acgtaccgggacatccagccgtacgtcgagatggtcgactcccagcaggagttccgcctc
tccttcttcgaggtcctcacgggcatggcgtacgcggccttcgcggacgcgcccgtcgac
gtggccgtcgtggaggtggggatgggcggcagctgggacgccacgaacgtgatcgacggg
gacgtcgccgtcgtgaccccgatcgatctggaccacaccgaccgcctcggtaccaccccc
ggggagatcgccaaggagaaggccgggatcgtcaagcaggacgcgacggtgatcctggcc
cagcagcccgtcgacgccgcccaggtgatgctcaagaaggccgtcgaggtcgatgccaca
gtcgcccgcgaggggctcgagttcggcgtcgtgagccgccaggtcgccgtcggcgggcag
ctgctgaccctccgggggctgggcggggagtacgacgaggtgtacatcccgctgcacggg
gcgtaccaggcgcacaacgcggcggtggcgctcgccgcggtggaggcgttcttcggggtc
gggtcccagcggcccgagccgctcgacatcgacacggtccgcaaggccttcgctgcggtg
tcctcgcccgggcggctggagatcgtgcggcggtcgccgacggtcgtgctggacgccgcg
cacaatccggcgggggcacgggcgaccgccgagggtgtccgtgaggtcttcgacttcagc
cggctgatcggtgtcgtggggtcgagcggggacaagaacgtacgggggctgctggaggcc
ttcgagccgatcttcaccgaggtcgtcgtcacgcagaactccagccaccgggccatggac
gtggactcgctcgccgcgatcgccgtcgaggtgttcggggacgaccgggtgcaggtcgag
tcccggctggacgatgccctggaggccgcgatcacgctggccgaggaggaggcggagtac
gcgggggccggggtgctggtgaccggttccgtgatcactgtgggcgaggcccggttgctg
ctggggaggggctga
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