Spodoptera litura (tobacco cutworm): 111357922 Help Entry 111357922         CDS       T08157                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism sliu  Spodoptera litura (tobacco cutworm) Brite KEGG Orthology (KO) [BR:sliu00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sliu04040]     111357922    04990 Domain-containing proteins not elsewhere classified [BR:sliu04990]     111357922 Ion channels [BR:sliu04040]  Voltage-gated cation channels   Ryanodine receptor    111357922 Domain-containing proteins not elsewhere classified [BR:sliu04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    111357922 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  111357922 NCBI-ProteinID:  XP_022828487 UniProt:  A0A9J7EHB1 LinkDB All DBs Position 26:6000521..6209647 Genome browser AA seq 5098 aa AA seqDB search MAEAEGGASEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDL SQCVFVIEQALSVRALQELVTAAGSETGKENLGKGTGSGHRTLLYGNAILLRHLNSDMYL ACLSTSSSQDKLAFDVGLQEHSQGEACWWTLHPASKQRSEGEKVRVGDDLILVSVATERY LHTTKENEVSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPST WTKDGGQNIVVYEGGSVMSQARSLWRLELARTKWAGGFINWYHPMRIRHITTGRYLGVND QNELYLVSREEATTASCAFCLRQEKDDQKQVLEDKDLEVIGAPIIKYGDSTVIVQHSETG LWLSYKSYETKKKGVGKVEEKQAILHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTK FINGLETLQENRRHSMFFASVNLGEMVMCLEDLINYFAQPDEDMEHEEKQNKFRALRNRQ DLFQEEGILNLILEAIDKINVITSQGFLAGFLAGDESGQSWEMISGYLYQLLAAIIKGNH TNCAQFANSNRLNWLFSRLGSQASGEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLL EKHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDYLLPGKNLLLQTALVDHVSSVRPNIFV GRVEGSAVYRKWYFEVTMDHIEKTTHMMPHLRIGWANTTGYVPYPGGGEKWGGNGVGDDL YSYGFDGAYLWSGGRKTQVNRTHAEEPYIRKGDVIGCALDLTVPIINFMFNGVRVTGSFT NFNLEGMFFPVISCSSKLSCRFLLGGEHGRLRYAAPEGYSPLVESLLPQQILSLEPCFYF GNLSKRALAGPPLVQDDTAFVPTPVDTLQIPLPSYVEQIRDKLAENIHEMWAMNKIEAGW MYGDQRDDLHKIHPCLVPFERLPPAEKRYDIQLAVQTLKTILALGYYISLDKPPARIRNV RLPNEPFMQSNGYKPAPLDLSAVTLTPKMDELVDQLAENTHNLWARERIQQGWTYGLNED PDMHRSPHLVPYPKVDDAIKKANRDTASETVRTLLVYGYNLDPPTGEQHEALLLEASKQK QAEFRTYRAEKNYAVGSGKWYFEFEILTAGPMRVGWAHADMAPGMMLGQDENSWAFDGYN EEKVFSGSTESFGKQWSVGDVVGVFLDLIDKTISFSLNGELLMDALGGETTFADVQGDNF VPACTLGVGQKARLTYGQDVNTLKYFTTCGLQEGYEPFCVNMKRDVTHWYTKDQPIFENT DEMIDTRIDVTRIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICHNEFIDEAEKA RRWVEIKERQQILMKEAVEAQMPAHIDQIMRSGFTMNDIKGLHYEDNQEEVPSSKVKRQP SRPPRKGSMTRGVSIQNYNNLQPGQVNGMHRSTSEAEMAKYDLGAQNLSPDDKKDKRGRS PFKFFRSKRGESSDRAKSRKSKTPDPFSDTEVSPERGPRRPNPQIKVSQANQRYNGMNAR PSRTNLYGSQVGLNMATPTQDRKQMTTSTLAQSTTETVGNEIFDAECLKLINEYFYGVRI FPGQDPTHVYIGWVTTQYHLHSKDFNQSKVTKSSVIITDDYDRVIENVNRQSCYMVRADE LYNEVMAEATAKGASQGMFIGCSVDTSTGTVSFTCEGKDTSFKFKMEPETKLFPAIFVEA TSKEILQIELGRSTTSLPLSAAVLPTSDKHVIPQFPPRLKVQCLKPHQWARVPNQSLQVH ALKLSDIRGWSMLCEDAVSMLALHIPEEDRCIDILELIEMDKLLSFHSHTLTLYAALCYQ SNYRAAHALCTHVDQKQLLYAIQSQYMSGPLRQGFYDLLIALHLESHATTMYVSLQFLFS RFSESITDISNLYSPYFPLEVVREFVMQALAEAVETNQVHNRDPVGGSNENLFLPLIKLV DRLLLVGMMRDEDVEKLLIMTNPETWDPSFDKEGKDEHRKGLLHMKMAEGAKLQMCYLLQ HLNDIQLRHRVEAIIAFAHDFVGDLQTDQLRRYTEIKQSDLPSAVAAKKTREFRCPPREQ MNAILSFKHLEEEDKENCPCGEELIARMNEFHESLMAHVSLNALQEPDGTENQEPEAKPG AFGKLYNIINTVKELEEEPKAIDEPPKKTPEEKFRKVLIQTIVNWAEESQIETPKLVREM FSLLVRQYDAVGELIRALEKTYVINAKTKLDVAEMWVGLSQIRALLPVQMSQEEEELMRK RLWKLVNNHTFFQHPDLIRVLRVHENVMAVMMNTLGRRAQAQSDAQPASPPVAEDNKEKD TSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLENSNILLSRPSLRGSTPLDVAYSSL MENTELALALREHYLEKIAVYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRFCVW VNGESVEENANLVIRLLIRRPECLGPALRGEGEGLLKAIVDANKMSERIADRRKLREMEQ EGDINFSHPLPESDEDEDYIDTGAAILNFYCTLVDLLGRCAPDAGVIALGKNESLRARAI LRSLVPLEDLQGVLSLRFTLNNPAAGEERPKSDMPSGLIPGHKQSVGLFLERVYGIETQE LFYKLLEEAFLPDLRAATMLDRNDGCESDMALSMNRYIGNSILPLLIKHAYFYNEAENYA SLLDATLHTVYRLSKNRMLTKGQREAVSDFLVALTSAMQPSMLLKLLRKLTVDVSKLSEY TTVALRLLTLHYERCAKYYGSTGAGQGVYGASSDEEKRLTMMLFSNIFDSLSKMDYEPEL FGKALPCLIAIGCALPPDYSLSKNYDDEFYGKEQVAGDLDNPQYDPQPINTSSVALNNDL NTIVQKFSEHYHDAWASRKIENGWVYGEGWSDSQKTHPRLKPYNMLNDYEKERYKEPVRE SLKALLAIGWSVEHSEVDIPSTNRSSMRRQSKSGGRPPDIVTDSATPFNYNPHPVDMTNL TLSREMQNMAERLADNAHDIWAKKKKEELVTNGGGIHPQLVPYDLLTDKEKKKDRERSQE FLKYLQYQGYKLHRPSKAPQSDTEQTTTGVAIELRFAYSLLEKLIQYIDRATINMKLLKP STTFSRRTSFKTSTRDIKFFSKVVLPLMEKYFSTHRNYFIAVATATNNVGAASLKEKEMV AALFCKLASLLRSRLAAFGPDVRITVRCLQVLVKGIDAKSLVKNCPEFIRTSMLTFFNNV ADDVGHTIMNLQDGKYAHLRGTHLKTSTSLGYINGVLLPILTAKFDHLANCEYGADLLLD EIQVASYKMLGSLYALGTDASLTHDRKYLKTEIERHKPALGSCLGAFSSTFPVAFLEPHL NKHNQFSLLNRIADHSLEAQDIMQKMEQCMPTLETILGEVDQFVESDKTYNEAPHIIDVV LPLLCSYLPFWWAQGPDNVTPTGGNHVTMVTAEHMNQLLKNVLKLIKKNIGNENAPWMTR IATYTQQIIINSSEELLRDSFLPLAERVRKRTDNMFHKEESLRGFIKSSTDDTSQVESQI QEDWQLLVRDIYSFYPLLIKYVDLQRNHWLRNNVPEAEELYNHVAEIFNIWSKSQYFLKE EQNFISANEIDNMVLIMPTATRRVTAVVDGTPQAGGKKKKKHRDKKRDKDKEVQASLMVA CLKRLLPVGLNLFAGREQELVQHCKDRFLKKMSEQDVAEFAKTQLTLPDKIDPADEMSWQ HYLYSKLGSKSKTNITVETAENKAKIIDDTVERIVAMSKVLFGLHMIDHPQQMSKNVYRS VVSIQRKRAVIACFRQTSLHSLPRHRACNIFARTYYELWLEEENVGQEVMIEDLTQSFED AELKKSDGEEEGEKPDPLTQLVTTFCRGAMTERSGALQEDPLYMSYAHIIAKSCGEEEEE GGGEEEEGGGEAEAEDEGRASIHEQEMEKQKLLFHQARLANRGVAEMVLLHISASKGLPS EMVMKTLQLGISILRGGNIDIQMGMLNHLKDKKDVGFFTSIAGLMNSCSVLDLDAFERNT KAEGLGVGLEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQNYLRTQAGNTTTVNVVI CTVDYLLRLQESIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLTEVIQGPCTQNQ QALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVN GTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSSASFQEIDANNDGWVLPKDFKEKM EQQKSYTPEEIEFLLACCETNHDGKLDYIGFCDRFHEPAKEIGFNLAVLLTNLSEHMPNE PRLARFLETAGSVLNYFEPFLGRIEIMGGSKRIERVYFEIKESNIEQWEKPQIKESKRAF FYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMAASEESVGGTKNREASYMYMGDDDD ERAGKDPFRRGLQSVKDGIYTAFSSLSPSNIKAKIADLQQMPPAELAVGFFKMFFLLFYY LGYGMLVVIRYIFGVLLGLMRGPQTDEPPPEPTEEEKIGQLRHRLLATQSSRHLPALPPA DDTGQMQVSAFGLDITKEDNGQIQVKPHESPSTSTPSSGEEAEVSPDENADHPEEQRPPS LIDLLGGEQAKKQAQERMEAQAAQQAAMSAIEAESKKAVQGPAPSALSQVDLSQYTRRAV SFLARNFYNLKYVALVLAFCINFVLLFYKVSTLDAEGGEGSGLGDIIAGSGSGSGSGSGD GGSGESGEDDDALEVVHIDEDFFYMEHVIKVAAVLHSIVSLAILIGYYHLKVPLAIFKRE KEIARKLEFDGLYIAEQPEDDDLKSHWDKLVISAKSFPVNYWDKFVKKKVRAKYSETYDF DSISNMLGMEKTSFSAQEEEGSKGLIHYIINIDWRYQVWKAGVTITDNSFLYSLWYFSFS VMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFF RKFYVQEEDDEVNRNCHDMLTCFVFNLYKGVRAGGGIGDELEPPDGDDSEVYRIIFDITF FFFIIVILLAILQGLIIDAFGELRDQLESVKEDMESNCFICGINKDYFDKVPHGFDTHVQ REHNLANYMFFLMHLINKPDTEYTGQETYVWNMYTQRCWDFFPVGDCFRKQYEDLMGE NT seq 15297 nt NT seq  +upstreamnt  +downstreamnt atggcggaagcggagggaggagcaagcgagcaagatgatgtttcattcttgcgtacggaa gacatggtctgcctgtcatgcacggcgactggcgagagagtgtgtttggcggccgagggg ttcggtaaccgacactgtttcctcgagaacatcgccgataagaacataccgccagatcta tcacagtgtgtgtttgtcatcgaacaggctttatcagtaagagcgttgcaagagttggtg acggctgcagggtctgaaactggaaaagaaaacttaggtaaaggcaccggttctggtcat cgtaccctgttgtacggcaatgctatcctactacgacatctcaacagtgacatgtacctg gcctgtctgtcgacttcttcatctcaggacaagctggcctttgacgtgggtctgcaagag cattcgcagggtgaagcctgctggtggacgctgcaccctgccagcaaacaaagatctgag ggtgagaaagtccgagtcggtgatgacttgattctggtatctgtggctactgaaagatac ttgcacactacaaaagaaaatgaagtatcgatagtgaacgcttcattccacgtgactcac tggtcagtgcaaccatacggtactggcatctctcgtatgaagtacgtgggttatgtcttc ggaggtgatgtcctgaggttcttccacggaggagacgagtgtctcaccatacccagtacg tggactaaagatgggggacagaatattgttgtctacgagggcggttccgtgatgtcacaa gctcgttcactatggcgcttagaactagctcgcaccaagtgggcaggaggcttcatcaac tggtaccacccaatgcgaatccgacacatcacgactggcagatacctcggagtcaatgac cagaatgagctgtatttagttagcagagaggaagccacaacagcgtcctgcgcgttctgc ctccgccaagagaaggacgatcagaagcaggtgctggaagacaaggacctggaagttata ggcgctccgatcatcaagtatggtgactccactgtcattgtacagcattcagagactggg ttgtggctctcttataagtcgtacgagacaaagaagaaaggagtaggtaaagtagaagag aagcaagcgatccttcacgaggaaggcaagatggacgacggactagacttctcaaggtca caagaggaggagtccaggactgctagagtcattaggaagtgttcgtctctgttcaccaag tttatcaatggtcttgaaactctgcaagagaaccgtcgtcattcgatgttcttcgcgtca gttaatcttggggagatggtgatgtgcctcgaggatctgatcaactacttcgctcagcca gatgaggatatggagcacgaagaaaaacagaacaaattccgcgcgctccgaaaccgtcag gacctgttccaagaggaaggtatcctcaacctgatcctcgaagccatcgacaagatcaac gtcatcacatcgcagggtttcttggctgggttcctggctggagacgagtctggacagagc tgggagatgatctcggggtacctgtatcagttgcttgcggccataataaagggcaaccac acgaactgcgcgcagttcgccaactcgaaccgcctgaactggttgttctcccggctcggc tcgcaggcgtcgggcgaggggaccggcatgttggacgtactacactgcgtgctcattgac tcgcctgaagctttgaatatgatgagggatgaacacataaaagtaattatctccctcctt gagaagcacggtcgtgacccgaaagtactagatgtcctatgttcactctgcgtcggtaac ggggtggcggtccgttcgtcacagaacaatatctgcgactatttactgcctggcaagaac ttgctattgcagactgccttagtagaccatgtgtccagtgttcgtccaaatatcttcgtg ggacgtgtagaagggtcggcagtgtaccgtaaatggtactttgaagtgaccatggaccac atcgagaagaccacacatatgatgccgcatcttagaatcggatgggctaatactactggc tacgttccctaccctggtggtggtgagaagtggggaggtaacggtgtgggagatgatcta tactcgtatggtttcgatggagcatacctctggtctggtggcaggaagacgcaggttaac aggacccacgctgaagaaccttatattaggaaaggtgatgtcatcggctgcgccttagac ctgacagtgcctatcatcaacttcatgttcaacggcgtgagagtgacaggctccttcacg aacttcaacctggagggcatgttcttccctgtcatcagctgttcgagcaagctgagttgt cgtttcctcctgggaggcgagcacggtcggctccgttacgcggccccggaggggtactct cccctggtggagtcgctccttcctcaacagatcctcagcctggagccatgcttctacttc gggaacttgtccaagcgagctctggctggtccaccgctagtacaggatgatacagctttc gtgccaactcctgttgatacgctgcagataccattaccttcatacgtggaacagatcaga gacaagctagctgaaaatattcatgaaatgtgggccatgaacaagatcgaagcaggttgg atgtacggagaccagcgcgatgacttgcacaagatccacccctgcctggtccccttcgag cgcctgcctcccgcggagaagagatacgacatacaacttgctgtgcaaacactcaagaca atcctggccctaggctactacatcagcttagacaagccgccggcgcgcatacgcaacgtt cgtctgccgaacgaaccgttcatgcagtcaaacggctacaagccagcacccctggacctg agtgctgtcaccctgacacccaagatggacgagctcgtggaccaactcgctgagaacact cacaatctatgggccagggagaggatccagcagggctggacatatggacttaatgaggac cccgacatgcaccgttccccccacctggtgccctacccgaaggtagacgatgccataaag aaggccaacagagatactgcctcggagactgtgaggactttactagtctacggatacaac ctggacccacccactggagaacagcatgaagccctcttgttagaagcatcaaaacagaag caagcagagttcagaacgtacagagctgaaaagaactatgctgtcggctccggaaagtgg tacttcgagttcgaaatccttacagctgggccgatgagggtgggttgggcccatgccgat atggctccaggcatgatgcttggccaagacgaaaactcctgggcattcgatggttacaat gaggaaaaagtgttcagcggtagcacagaatcgttcggcaagcaatggtctgtgggagac gtagtcggcgtgttcctagatctcattgataagacgataagtttctctctgaacggagag ctgttgatggacgctctcggtggagagaccacattcgcagatgttcagggcgataacttc gtaccagcttgcactttgggagtgggacagaaagccagattaacatacggtcaagatgtg aacaccctgaaatatttcacgacgtgcggtcttcaggagggctatgagccattctgtgtc aacatgaaacgcgacgtgacacactggtacacgaaggaccagcccatcttcgagaacacg gacgagatgatcgacaccaggattgatgttactaggatacctgctggatctgacacgcca ccgtgcttgaaaatatctcacaacacattcgagactatggaaaaagcgaactgggagttc ttgcgactgtcactacccgtcatctgccacaacgagtttatcgatgaagcagaaaaagcc aggcgctgggtggaaatcaaggaacgccagcagattctgatgaaggaggccgtggaagct cagatgcctgctcacatcgaccagatcatgaggagtggcttcaccatgaatgatattaaa ggtttgcactacgaggacaatcaggaagaggtcccaagttcgaaggtcaagcggcaaccg tcgagacctccacgtaagggttcgatgaccagaggcgtgtctatacaaaattacaataat ttacaaccaggtcaagtaaacggtatgcatcggtcgaccagtgaggctgagatggctaaa tacgacttgggagcacagaacttgagtcctgatgataagaaggataaacgaggacggtca cctttcaagttcttcagaagcaaacgaggtgaaagcagcgaccgtgccaagagtcgtaag tccaagacaccagatccattcagtgacaccgaagtatcccctgaacgtggacctcgaaga ccaaaccctcagatcaaagtgtcacaggcgaatcaaagatataacggcatgaacgcgcgc cctagtcggaccaacttgtacggaagccaagttggtctcaacatggcgacgcctacgcaa gacaggaaacaaatgactacgagcactcttgcgcagtctacgacggaaactgttggcaat gagatcttcgacgctgagtgcttgaagctcatcaatgaatacttttatggagttaggata ttccccggtcaagatccgacacatgtgtacataggttgggtgacgacccagtaccatctt cactccaaggacttcaaccagagcaaggtgaccaagtcatcggttatcatcaccgatgat tacgacagggttatcgaaaatgtaaaccgccaatcctgctacatggtgcgcgctgacgag ctgtacaacgaggtgatggctgaagccacagctaagggagcgtcccaaggcatgttcatt gggtgctccgtggatacctccactggcactgtctcctttacttgtgagggcaaggatact agctttaaattcaagatggaaccagaaacgaagctgttcccagcaatcttcgtggaggcg acgtcgaaggagatcctccagatagaactgggaaggtctaccaccagcctgcctctgtcg gccgcagtgctcccgaccagtgacaagcacgtcatcccccagttcccccccaggttgaaa gtgcagtgcttgaagccacatcagtgggctagagtaccgaaccaatccttacaagtacac gctctgaagttgtcagacatccgcggttggtccatgctgtgtgaggatgcagtgtctatg ctagcgttgcatataccagaggaagaccgttgcatagacattctagaactaatagaaatg gacaaacttctaagtttccactcacacacactcacgctgtatgccgcattgtgttaccag agtaactatagggcggcgcacgcgctgtgcacgcacgtggaccagaagcagttgctgtac gcgatccagtcgcagtacatgtcgggcccgctgcgacaaggcttctacgatctactcatc gcgctgcatctcgagtcacatgctaccaccatgtatgtatcactgcaatttctattttcc cgtttcagtgaaagcataacagacattagcaacctatactcgccgtacttcccgctggag gtggtccgtgagttcgtgatgcaagctctggcggaggccgtggagaccaaccaggtccat aacagggatcctgtaggaggcagcaatgagaacctgttcctgccattaataaagctagta gaccgactactcttagtcggaatgatgcgcgatgaagatgttgagaagctgctcatcatg actaacccagaaacgtgggacccttcgtttgacaaagaaggtaaagacgagcaccgcaaa ggtctacttcacatgaaaatggccgaaggcgcaaagttacagatgtgttacctactacaa catctgaacgacatacagctgagacacagggtcgaagctatcattgcgtttgcgcatgac ttcgttggagatctacagactgatcagttgagacgttacacagagatcaagcagtcagac ctgcccagcgcggtagcagctaagaagacgagagagttccgttgcccacccagagaacaa atgaacgcaatcttgagtttcaagcacttggaagaagaagacaaagagaactgtccatgt ggagaggaacttatcgccaggatgaacgagttccacgagagtctgatggcacatgtgtcg cttaatgctttacaggaaccggatggcacggagaaccaagaacctgaagcgaaaccaggt gcctttggcaagttgtacaacatcatcaacactgtgaaggaacttgaagaagaacccaag gctatcgatgagccaccaaagaagaccccagaagagaagttccgtaaggtcttaatccag accatcgtcaactgggctgaggagtcgcagattgaaactcccaaactggtcagggagatg ttcagtctcctagtccgtcaatacgacgcagtgggcgagttgatccgtgccctggagaag acgtacgtcatcaatgcgaagaccaagttggacgtggcagagatgtgggtcggactcagt cagatccgagctcttctaccggtacagatgagtcaggaggaagaggaacttatgcggaag aggctttggaaactcgtcaacaaccacacgtttttccaacatccagacttgataagagtg ctccgcgtgcacgagaacgtgatggcggtgatgatgaacacgctgggccgccgcgcgcag gcgcagtccgacgcgcagcccgcctcgccgcccgtcgcagaggacaacaaggagaaggac acatcccacgagatggtagtagcgtgttgtcgtttcctctgctacttctgtcgtacggga cgacagaaccagaaggcaatgttcgatcacttcgacttcctgctggagaactccaacatc ttgctgtccagaccctcgttgagaggttccacgcctctagacgtggcgtattccagtttg atggagaatactgagctggctttggctttgagggagcactacctagaaaagatagcagtg tacctttctcgctgtggactacagagcaactcggagctcgtcgagaaaggatacccggac cttgggtgggatccagtcgagggcgaacgttacctggacttcctacgattctgtgtctgg gttaacggtgaaagcgtagaagagaacgcgaacttagtgatccgtcttctgatccgtcgt ccagagtgcttgggtcccgccctcagaggagagggtgagggtctactgaaggccatcgta gacgctaataaaatgagtgagaggatcgcagacaggaggaaactgagggagatggagcaa gaaggggatattaatttcagtcacccgctccccgagtccgacgaggacgaggactacatc gacactggcgccgccatacttaacttctactgtactctagtggacttgctgggacggtgc gcgcctgatgcaggggttattgcactgggcaaaaacgagtccctccgagcccgcgccatc ctccgttccttggtgcccctggaggacctgcagggagtgctgagtctgaggttcacgctc aacaaccccgctgcaggagaggagagacctaagtctgacatgccgtcagggctgatcccc ggccacaagcagagcgtgggtctgttcctggagcgagtgtacggcatagagacccaggaa ctgttctacaagttgttggaggaagcgttcctacctgacctcagggcggctaccatgctg gataggaacgacggttgcgagtccgacatggctctctcgatgaaccgctacatcgggaac tccatcctgcctctactgatcaaacacgcctacttctacaacgaggccgagaactacgcc agtctcctggacgccacgctacatactgtttataggttatcaaagaaccgcatgttaacc aagggtcagcgtgaggcggtgtcagacttcctagtcgccctaacatcggccatgcagcct tctatgttgttgaaactattgaggaaactgacagtggatgtgtccaagctgtcggagtac acgactgtcgctcttaggcttctaacccttcactacgagcgttgtgccaagtactacggt agtacaggagccggccaaggcgtgtacggagcatcatcagacgaggagaagaggctcacc atgatgctattctcaaacatcttcgattccctcagcaagatggactatgagcctgaactc tttgggaaggcgttgccatgtttgattgctattggatgcgctttaccacccgattattcg ctttccaagaactatgacgatgaattctacggcaaagaacaagtagctggtgacctagac aatcctcaatacgaccctcagccgatcaacacatcatcagtagccctcaacaatgactta aacacaatagtccagaagttctcagaacattaccacgatgcctgggcttctaggaagatc gagaacggatgggtctacggagaaggatggtctgatagccagaagacgcatccacgactg aaaccgtataatatgcttaatgactatgaaaaggagcgttacaaggaaccagttcgtgaa tctttgaaagcccttctagccatcggatggtcagtggaacattcagaagtggacatacca agcaccaaccgcagttccatgagaaggcaatccaaatcgggaggccgccctcccgatatt gtgacggactcagcaactcccttcaactacaacccgcacccagtagacatgaccaacttg acgctatcaagagagatgcagaatatggcagaaagactggctgataatgcccacgatatc tgggctaagaagaagaaagaagagcttgttactaatggaggaggtatccacccacaactc gtaccctatgatctcttaacagacaaagagaagaagaaggacagagagagatcgcaagag ttcctcaaatatttacaataccagggttacaaactacacaggccaagcaaggcaccacag agtgatacggaacagaccactacgggcgtagcaatagagctcagattcgcatactcgtta ctggagaagttgatacagtatatagatagagcgaccatcaatatgaagctcttgaaacct tctactactttcagtaggagaactagttttaaaactagtacgagggatattaagttcttt tctaaggtggtgctgcctctgatggagaagtacttctcaacgcatagaaactacttcata gcagtagctactgctaccaacaatgtgggtgctgccagtttaaaggagaaagagatggtt gcagccctattctgtaaactggccagtttacttagatctagactcgcagctttcggtcct gatgtccgcatcaccgtccgttgtctccaagtgctggtcaaaggcatcgacgccaagtct ctggtgaagaactgccccgagttcatcaggacatccatgttgaccttcttcaataatgtc gctgatgatgtagggcataccatcatgaatcttcaggatggtaaatacgcacatctccga ggtacacacttgaagacttccacttcacttggctacatcaacggagttctactaccaata ctgacggccaagtttgatcacttggccaactgcgagtacggagctgacctactattggat gagatccaagtggcttcatacaaaatgctgggttcactgtacgctttaggcactgacgcg tccctcacacacgacagaaaatacctcaagactgaaatcgagagacataaacctgctttg ggttcgtgcctcggtgcgttcagctcgacattcccagtggcgttcttggagccccacttg aacaaacacaatcagttctccttgctgaacaggatcgctgaccactctttggaggctcaa gatataatgcagaaaatggaacaatgcatgccgacactagaaacgatcttgggtgaagtg gaccagttcgtggagtctgataagacttacaacgaagctcctcatattattgatgtggtg ttgcctttactctgctcttacttgccgttctggtgggcacagggacctgataacgttact cctactggaggcaaccatgtaacaatggtgacagcagaacacatgaaccaacttctaaag aacgttctgaagcttatcaagaagaacataggcaatgagaacgctccatggatgacgcgc atagctacctacacccaacagatcatcatcaacagttcagaggaactcctcagggactcc ttccttcctctcgctgagagggtccgaaagaggaccgataatatgttccataaggaggag agcttgagaggatttattaagtcatcaactgacgatacatctcaagtagaatctcaaatc caagaagactggcagctgttggttcgtgacatttattccttctacccactgctcatcaaa tatgtagacttacaaagaaaccactggctcaggaacaacgtgccagaggctgaagagctt tacaaccacgtagctgaaattttcaacatctggtccaagagtcagtacttcttgaaagaa gagcagaacttcatatctgctaatgagattgataacatggtactgatcatgccaacagca actagaagggtaacagcagttgtagacggtactccacaagccggtggcaagaaaaagaag aagcaccgcgataagaagcgagataaagacaaagaagtccaagcctctctaatggtggcc tgtctcaaaagacttctgccagtaggcctgaacctcttcgcaggtagagagcaggaactg gtacagcattgcaaagacaggttcctgaagaaaatgtctgaacaagatgtagctgaattt gcgaaaacacaattgacattgcctgataaaattgacccagctgatgaaatgtcttggcaa cattatttgtatagcaaactgggttctaagagtaaaacgaatataactgttgagactgct gagaataaagctaaaataattgatgacaccgtggaaaggattgttgctatgagcaaagtg ctgtttggattacatatgattgaccatccccaacaaatgagtaagaatgtctaccgttca gtggtgtctatccaacgtaagcgagctgtcatcgcttgcttcagacaaacgtcgctacat tctctgccgagacatcgagcgtgtaatatattcgctcgaacatattacgagctgtggctg gaagaagagaacgttggccaagaagtcatgattgaagatcttacgcaatcgttcgaagac gcggagctgaagaagagcgacggtgaggaggagggagagaagcctgatcctctgacacag ctagtcaccaccttctgcaggggagccatgactgagagatctggagcgttgcaggaggat cccctctacatgtcttacgcacacatcatagcgaagtcctgtggagaagaagaggaagaa gggggcggggaagaagaagagggcgggggtgaagccgaggcagaagatgagggcagagcc agtatacatgaacaagaaatggaaaaacagaagctcctcttccatcaagctcgtctagcg aacaggggtgtggcagagatggtgctcctccatatatctgcgtccaaggggctacctagc gagatggtgatgaagactctacagctgggaatctctatacttaggggaggcaatattgat atacagatgggtatgctgaaccatctgaaagacaaaaaagacgtcggtttcttcacttcg atagctggtctcatgaactcctgttccgtgctcgatctggacgccttcgagaggaatact aaggctgaaggtctgggagtgggcctggaaggcgcggcaggtgagaagaacatgcacgac gcggagttcacgtgcgcactgttccggttcatacaacttacttgtgaaggacacaacttg gactggcagaactatctcagaacgcaggctggtaacacgacgacagtgaacgtcgtcatc tgtaccgtcgactatctgctgcggctacaggagtccatcatggacttctactggcattac tccagcaaggagttaatcgatccagctggcaaggcgaacttcttcaaggcgataggtgtc gcgtcccaagtgttcaacactctcactgaggtcatccagggaccttgtacacagaaccaa caggctctggcacactctaggttatgggacgcagtaggtggtttcctgttcctattctcc cacatgcaggacaagttgtcgaaacactcgtcccaggtggacctgctgaaggaactcctc aacctgcagaaggatatgatcactatgatgctgtctatgctggaaggaaacgttgttaac ggcactatcggtaagcagatggtggatacgctagtagaatctgcatccaacgtggagctg atcctgaaatacttcgacatgttcctgaaactgaaggacctgacatctagcgccagcttc caggagattgatgctaataatgatggatgggtgctgcctaaggactttaaggagaagatg gaacagcagaagagttatacacctgaagaaatcgagttcctcctagcatgctgtgagacg aaccacgatgggaaactggactacatcggcttctgtgaccggttccatgaacctgccaag gagatcgggttcaacttggctgtactgctcaccaatttgtctgaacatatgcctaatgaa cccaggttggcccgtttcctagagacagctggttctgtcctgaactacttcgagccattc ctcggtcgcatcgagatcatgggcggctccaagcggatagagcgagtctacttcgagatc aaggagtctaacatcgaacagtgggagaaaccacagattaaggaatccaaacgcgcattc ttctacagcatagtaacagaaggaggagacaaggagaagttggaggccttcgtcaacttc tgtgaggacgccatctttgaaatgactcacgcgtccggactcatggccgcgtccgaggag tctgtcgggggaaccaagaatagggaggctagctacatgtatatgggagatgatgatgat gagagagccggcaaagatccattccgtcgtggtctccaatcagtaaaagacggcatctac acagcattctcatccttatccccatcgaacataaaggcgaaaatcgcagatctccaacaa atgccgccagcagaacttgcagtgggcttcttcaaaatgttcttcctattattctattac ttgggctacggaatgctcgtcgtgatcaggtacatattcggcgtccttctcggtctgatg agaggtccacagacggacgaaccgccgcccgaaccgacagaggaggagaaaatcggtcag ttaagacacaggttgctagccacacaaagttctcgacatctaccagcgttaccaccagct gacgacactgggcagatgcaggtctccgcattcggactggatatcactaaagaagacaat ggacagatacaggtaaaaccgcacgagtcaccgagcacatcaacgccatcttccggcgag gaggctgaagtatctcctgatgagaacgccgaccatcctgaggaacagagaccaccgtca ctcatcgatctacttggaggagaacaagcgaagaagcaggctcaagaacgtatggaagcg caggctgcccaacaagctgctatgtccgctattgaagctgagagcaaaaaggcagtccaa ggtccggctccatcagcgttatcacaagtggacctgtcccagtacaccaggcgtgcggtc tccttcttggctcgaaacttctataatttgaaatacgtcgccctcgtcttggctttctgt atcaactttgtactgctgttctataaggtgtctacgttggacgcggaaggtggcgagggt tctggtctgggcgatatcatcgctggatctggatcgggctcaggatctggcagtggagat ggtggtagcggtgaatcaggtgaagacgacgatgctttagaagtggtacatatagacgag gacttcttctacatggagcatgtcatcaaagtggccgccgtactgcactccatcgtgtct ctggctatacttattggatattaccatcttaaggtgccactagctatcttcaagcgtgag aaagagatcgcccgtaagctggagtttgatggtctttacatcgctgagcagccagaagac gacgacctcaagagccactgggataaacttgttatatctgccaaatcgttcccggtgaac tattgggataagttcgtgaagaagaaggttcgtgccaagtactccgagacttatgacttc gactccatatccaacatgctgggcatggagaagacttccttctctgctcaagaagaagaa ggcagcaagggactgattcattacataatcaatatagactggcgttaccaagtatggaag gcgggagtgacgatcacagacaactccttcctctattctctatggtacttctcattctcc gtgatgggtaacttcaacaacttcttcttcgctgcccatctactagatgtcgctgttgga ttcaaaactttgagaaccattctacagtccgtcacgcataatggaaaacagctggtcctg acggtgatgctgcttaccatcatagtgtatatctataccgtgatagcgttcaacttcttc cgcaagttctacgtgcaggaggaagacgacgaggtcaataggaactgccatgatatgctt acgtgcttcgtattcaacctgtataaaggagtacgagccggcggcggtattggcgacgag ctggagccgcccgatggagacgactccgaggtctaccgcatcatattcgacatcacattc ttcttcttcatcatcgtcatcctgctggctattctgcagggtttgatcatcgacgcgttc ggtgaactgcgtgatcagttggagtcggtgaaggaagacatggagtccaactgcttcatc tgtggcattaataaagactattttgataaagtgccgcacgggttcgacactcacgtccag agagagcataatctagcgaactacatgttcttccttatgcatctcattaataagcccgat acggaatatacaggtcaagaaacgtatgtatggaatatgtacacgcaacgatgctgggac ttcttccctgtcggagactgcttcaggaaacagtatgaagatctaatgggagaatag

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