Streptomyces lunaelactis: SLUN_00380
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Entry
SLUN_00380 CDS
T06347
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
slk
Streptomyces lunaelactis
Pathway
slk00300
Lysine biosynthesis
slk00550
Peptidoglycan biosynthesis
slk01100
Metabolic pathways
slk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SLUN_00380
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SLUN_00380
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SLUN_00380
Enzymes [BR:
slk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SLUN_00380
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
TPP_enzyme_M
Motif
Other DBs
NCBI-ProteinID:
AVZ70951
UniProt:
A0A2R4SVQ5
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All DBs
Position
complement(74462..75847)
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AA seq
461 aa
AA seq
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MIPLTLAEIADATGGTLDHITDPHTRVTGPLSFDSRHVAPGGLFACLAGSTVDGHAFAAQ
AVRDGAVAALTTRPVDAPAIIVPDVLDAMGRIATAVAAAYTGTVIALTGSAGKTSTKDIL
ETVLSQHGPTAANERSFNNEIGFPVTVSRVMPDSRYLVLEMGARGKGHIASLCQMARPRI
ATVLGIGSAHVGEFGSQLAIADAKAEIVRALPDHGVAILNGDDPLVAAMVHDTSAQVLLF
GTGSHCDVRAEEISVNSHGQPNFTLHHGHHHSLVQLRVHGRHNVTNALAAAATAIAAGVP
FDRIVTGLTEAELSSGARMEILQRADGVTIINDAFNASPESVIAALDALADMAGTNRRSV
AVLGEMAELGDDAPAWHDKVADKVLAVGVDRLIGIGGAHTLRMIGTVREGSGHATEADST
IPLAQHVNTLLQPHDVVLVKGANALGLEATARELAGMCTTR
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
gtgatccccctgaccctcgccgagatcgccgacgcgaccggcggcactctggaccacatc
accgacccgcacacccgagtcaccggcccgctgtcgttcgactcacgccatgtcgccccc
ggagggctgttcgcctgcctcgctggcagcaccgtggacgggcacgcgttcgccgcgcag
gcggtacgcgacggcgccgtcgctgcgctcaccacgcgcccggtcgatgcaccggccatc
atcgtgccggatgttctcgacgccatgggccgcatcgccaccgcggtcgccgccgcctac
accggcaccgtcatcgccctgaccggctcggcaggcaagaccagtaccaaggacatcctc
gagaccgtcctcagccagcacgggcccaccgccgccaatgagcggtccttcaacaacgag
atcggattccccgtcaccgtcagccgcgtgatgcccgacagccgctacctggtgctggaa
atgggagcccggggcaagggccacatcgcctccctgtgccaaatggcccgccctcgcatc
gccaccgttctcggcatcggatcagcgcacgtcggcgagttcggcagccaactcgccatc
gccgacgccaaggccgaaatcgtccgagcactccccgatcacggcgtggccatcctcaac
ggcgacgacccgctcgtagcagcaatggtccacgacaccagcgcgcaggtgctgctgttc
ggcaccggcagccactgcgacgtacgagccgaggaaatcagcgtcaactcccacggccag
ccgaacttcacactccaccatggacaccaccacagcttggtgcagctccgtgtccacggc
cggcacaacgtcaccaacgcgctcgccgccgccgcaaccgccatcgccgcaggcgtcccc
ttcgaccgcatcgtcaccggtctcacagaagcagaactgtcctccggggcccgcatggag
atcctgcagcgcgccgacggagtcaccatcatcaacgacgcattcaacgcctcgccggag
tccgtcatcgccgcactcgacgccctcgccgacatggccggcaccaaccgccgcagcgtc
gccgtcctcggagagatggccgaactcggcgacgacgcacccgcatggcacgacaaagtc
gcggacaaggtcctcgccgtcggcgtcgaccggctgatcggaatcggcggcgcgcacacc
ctccgaatgatcggcaccgttcgggagggcagcgggcacgccacagaagccgactcgacc
attcccctcgctcagcacgtcaacacgctcctccagccccatgacgtcgttctggtcaag
ggcgccaacgccctcggccttgaagcaaccgcacgcgaactggccggcatgtgcacaact
aggtag
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