Streptomyces lunaelactis: SLUN_22785
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Entry
SLUN_22785 CDS
T06347
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
slk
Streptomyces lunaelactis
Pathway
slk00860
Porphyrin metabolism
slk01100
Metabolic pathways
slk01110
Biosynthesis of secondary metabolites
slk01120
Microbial metabolism in diverse environments
slk01240
Biosynthesis of cofactors
Module
slk_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
slk_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
slk_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
slk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SLUN_22785
Enzymes [BR:
slk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SLUN_22785
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SLUN_22785
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AVZ74569
UniProt:
A0A2R4T5Z3
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Position
4948226..4949893
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AA seq
555 aa
AA seq
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MSPTRPTANASSVFSAHGHVTFLGAGPGDPGLLTLRAVEALAGADVLIAEPEVLDVVRSH
ARANVSTPELTVVDDASTAAGIPVLRDAANLVMEAARGGKRVVRAVTGDPGLDGNAGQEM
LACAAEGIPFEVVPGVATSVGVPAYAGVPLRDAQGTDVRFIDARSASERCWTEVGASDGT
AVVSATLETVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWSATLGTIAQVLKQAKVLP
SPEGHRPVIAVVGERSSAAQRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVP
HEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGI
KVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATE
TLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGK
PHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAEFGARRREAAVEAGEHVT
RPSERRPGGRRRRTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccacccgtcccaccgccaacgcatcctcggtgttctcggcacacgggcacgtc
accttcctcggcgccggtcccggcgaccccggactgctgactctgcgcgctgtcgaggcg
ctcgcgggagccgacgtactgatcgccgagccggaagtgctcgacgttgtacgcagccat
gcgcgggcgaacgtaagcacgcctgaactgacggttgttgacgacgcgtcaacagccgcc
gggatccccgtcctcagggatgcggccaatcttgtcatggaggccgcgaggggtggcaag
cgggtcgtccgtgcggtcaccggtgacccgggcctcgacggaaacgcaggtcaggagatg
ctcgcctgcgccgccgaggggattcccttcgaggtcgtgccgggtgtcgccacgtcggtc
ggcgtacccgcgtacgccggtgtaccgctgcgcgacgcgcagggcacggacgtacgtttc
atcgacgcccgcagcgcgagtgagcggtgctggaccgaagtcggcgcgagcgacggcacg
gccgtcgtctcggcgacgctggagacggtcgccgcggcggcgggcgagctggtggccgcg
ggccgcaagccggacaccccgctgaccgtcaccgtcgccggtacgacgaccaggcagcgg
acgtggtccgcgaccctcgggacgatcgcacaggtcctcaagcaggcgaaggtacttccc
tcgcccgagggccaccggcccgtcatagccgtggtcggtgagcgcagttccgccgcccag
cgcgaccagctctcgtggttcgagtccaagccgctcttcggctggaaggtgctcgtaccg
cggaccaaggagcaggcggcttcgctctccgaccagctgcgcagctacggtgctgtgccg
cacgaggtgccgacgatcgccgtcgagccgccgcgtacgccgcagcagatggagcgggcg
gtcaaggggctcgtgaccggtcgctatgagtggatcgccttcacgtcggtcaacgcggtg
aaggcggtgcgggagaagttcgaggagtacgggctcgatgcccgtgcgttcgcggggatc
aaggtcgcggcggtgggggagcagaccgctgccgcgctggtggacttcggtgtgaagccg
gacctcgtgccgagcggtgagcagtcggccgcgggtctgctggaggactggccgccgtac
gatccggtcttcgatccgatcgaccgggttttcctgccgcgggcggacatcgccaccgag
acgctggtggcgggcctgatcgagctcgggtgggaggtcgacgacgtgaccgcgtaccgg
acggtgcgcgcgtcgccgccgccggcggacacgcgggaggcgatcaagggcggcgggttc
gatgccgtgctgttcacgtcgtcctcgacggtgcggaatctggtggggatcgccggcaag
ccgcacaacgtgaccgtgatcgcgtgcatcggccctgctacggcgaagaccgcggaggag
cacgggctgcgggtggacgtgctgtcaccggagccgtcggtgcacaagctggcggaggcg
ctggcggagttcggcgcgaggcgccgcgaggcggcggtggaggcgggcgagcatgtgacg
cggccttcggagcggcgtcctggcggacggcggcggcggacgacgtag
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