Streptomyces lunaelactis: SLUN_24470
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Entry
SLUN_24470 CDS
T06347
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
slk
Streptomyces lunaelactis
Pathway
slk00230
Purine metabolism
slk00670
One carbon pool by folate
slk01100
Metabolic pathways
slk01110
Biosynthesis of secondary metabolites
Module
slk_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
slk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SLUN_24470 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SLUN_24470 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
slk04147
]
SLUN_24470 (purH)
Enzymes [BR:
slk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
SLUN_24470 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
SLUN_24470 (purH)
Exosome [BR:
slk04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
SLUN_24470 (purH)
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
AVZ74858
UniProt:
A0A2R4T6V4
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Position
5290192..5291757
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AA seq
521 aa
AA seq
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MTVEAAKRAIRRALVSVYDKTGLEDLARGLHEAGVELVSTGSTAAKIAAAGVPVTKVEEL
TGFPECLDGRVKTLHPRVHAGILADLRLDAHREQLAELGVEPFELVIVNLYPFRETVASG
ATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPARYADVLAAAKEGGFDLAARKRLAAE
AFQHTAAYDVAVASWFTNVYAPEEGAVLPEFLAGAWDRKATLRYGENPHQAAALYVDGRP
GGLANAEQLHGKEMSFNNYVDTEAARRASFEHEAPCVAIIKHANPCGIAVGADVAEAHRK
AHACDPLSAFGGVIAVNRPVSVAMAEQVAEIFTEVIAAPAYEDGALEVLARKKNIRVLKV
DGTPLQPGDLKPVSGGALLQQSDAFQAEGDDPANWTLATGEALSADGLADLAFAWRACRA
VKSNAILLAKGGASVGVGMGQVNRVDSAKLAVERAGAERAQGSFAASDAFFPFPDGLEIL
VAAGVKAVVQPGGSVRDELVIEAAKKAGVTMYFTGTRHFFH
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
gtgactgttgaggctgcgaagcgggccatccggcgagcgctggtcagtgtttatgacaag
acgggtcttgaggaccttgcccgtgggctgcacgaggcgggcgtggagctggtctccacc
ggctcgaccgccgcgaagatcgccgctgccggggtgccggtcaccaaggtcgaggagctc
accggcttccccgagtgcctcgacgggcgggtcaagacgctgcacccgcgcgtgcacgcc
gggatcctcgccgacctgcgcctcgacgcgcaccgtgagcagctcgctgagctgggcgtg
gagccgttcgagctggtgatcgtgaacctgtacccgttccgggagacggtcgcctccggc
gccacccccgacgagtgcgtcgagcagatcgacatcggcggcccctcgatggtccgcgcc
gccgccaagaaccacccctccgtcgcggtcgtcaccagccccgcgcggtacgcggacgtg
ctcgccgccgccaaggagggcggcttcgacctcgccgcccgcaagcggctggccgcggag
gcgttccagcacaccgccgcgtacgacgtcgccgtcgcctcctggttcaccaatgtgtac
gcccccgaggagggcgcggtcctccccgagttcctcgcgggggcctgggaccggaaggcc
accctccgctacggcgagaacccgcaccaggccgccgcgctgtacgtggacggccggccg
ggcggactcgccaacgccgagcagctgcacggcaaggagatgtccttcaacaactacgtg
gacaccgaggccgcccgccgcgcctccttcgagcacgaggcgccctgcgtcgcgatcatc
aagcacgccaacccgtgcggcatcgcggtcggcgcggatgtcgccgaggcacaccgcaag
gcgcacgcctgcgacccgctctccgcgttcggcggcgtcatcgccgtcaaccgcccggtc
agcgtggcgatggccgagcaggtcgcggagatcttcaccgaggtcatcgcggccccggcg
tacgaggacggggcgctcgaggtcctcgcccgcaagaagaacatccgcgttctgaaggtc
gacggcaccccgctccagcccggcgacctcaagccggtctcgggcggcgcgctgctccag
cagtccgacgcgttccaggccgagggcgacgaccccgcgaactggacgctggccacgggc
gaggcgctgtccgccgacgggctcgccgacctcgccttcgcctggcgcgcctgtcgcgcg
gtcaagtccaacgcgatcctgctcgccaagggcggcgcgtccgtgggcgtcggcatgggc
caggtcaaccgcgtcgactccgcgaagctcgcggtcgagcgggcgggcgcggagcgcgcg
cagggttcgttcgccgcgtcggacgcgttcttcccgttcccggacggcctggagatcctg
gtcgcggcgggcgtcaaggctgtggtgcagccgggcggttcggtgcgggacgagctggtg
atcgaggcggcgaagaaggcgggcgtgacgatgtacttcacgggtacgcggcacttcttc
cactga
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