KEGG   Streptomyces lincolnensis: SLINC_1742
Entry
SLINC_1742        CDS       T04801                                 
Name
(GenBank) uroporphyrin-III methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
sls  Streptomyces lincolnensis
Pathway
sls00860  Porphyrin metabolism
sls01100  Metabolic pathways
sls01110  Biosynthesis of secondary metabolites
sls01120  Microbial metabolism in diverse environments
sls01240  Biosynthesis of cofactors
Module
sls_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:sls00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    SLINC_1742
Enzymes [BR:sls01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     SLINC_1742
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     SLINC_1742
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     SLINC_1742
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 Radical_SAM
Other DBs
NCBI-ProteinID: ANS63966
UniProt: A0A1B1M5M2
LinkDB
Position
complement(2091787..2093028)
AA seq 413 aa
MAEHPAYPVGLRLTGRRVVVLGGGQVAQRRLPALIAAGADIVLVSPGATPSVEAMADAGE
ITWEQRPYREGDLADAWYALIATGDTEANTRASAEAERHRVWCVRSDDADRATAWTPATG
HSEGVTIAVLTTDAKGRDPRHTAAIRDAVVEGLRDGTLVAPHHRTRTPGVALVGGGPGDP
DLITVRGRRLLAEADVVITDHLGPRDLLAELPASVEVIDAAKLPYGRFMAQEAINDALIE
HAKQGKSVVRLKGGDPFVYGRGMEEVQALAEAGVPCTVVPGISSSISVPGAAGIPVTHRG
VAHEFTVVSGHIAPDDERSLVDWPSLAKLTGTLVILMGVGTIGKVAETLIAHGKSPEIPV
ALVQEGTTAAQRRVDATLATVADVVREQDVKPPAVIVIGEVVAVGPRTSTTLA
NT seq 1242 nt   +upstreamnt  +downstreamnt
atggccgaacaccccgcctaccccgtaggcctccgcctcaccggccgtcgcgtcgtcgtt
ctcggcggcggccaggtcgcccagcgccgcctgccggccctcatcgcggcgggcgcggac
atcgtcctcgtgtcgcccggagcgaccccctcggtcgaggcgatggcggacgcgggcgag
atcacctgggagcagcggccgtaccgggagggcgacctcgccgacgcctggtacgccctc
atcgccaccggtgacacggaagccaacacccgggcctccgcggaggccgagcgccaccgc
gtgtggtgcgtccgctccgacgacgctgaccgggccacggcctggacccccgccaccggc
cacagcgagggcgttacgatcgccgtcctgaccaccgacgccaagggccgcgacccccgc
cacaccgcggcgatccgcgacgccgtggtcgagggcctgcgcgacggcacgctcgtggcc
ccgcaccaccgcacccgtacgcccggcgtcgccctggtcggcggcggccccggcgacccg
gatctcatcacggtccgcggccgccgcctgctcgccgaggccgacgtggtcatcaccgat
cacctcggcccgcgcgacctgctcgcggaactgccggcgagcgtcgaggtcatcgacgcg
gcgaagctgccgtacggccgtttcatggcccaggaggccatcaacgacgcgctgatcgag
catgccaagcagggcaagtcggtggtccgcctcaagggtggcgaccccttcgtctacggc
cgtggcatggaggaggtccaggcgctggccgaggccggcgtcccgtgcacggtcgtgccc
ggcatctccagctcgatctcggttccgggcgccgccgggatccccgtcacccaccggggc
gtcgcccacgagttcaccgtggtcagcgggcacatcgcgccggacgacgaacgctccctg
gtcgactggccgtccctcgccaagctgaccggcacgctggtgatcctcatgggcgtcggc
accatcgggaaggtcgccgagacgctcatcgcccacggcaagtcccccgagatccccgtc
gccctggtccaggaggggacgacggccgcccagcgccgggtcgacgccaccctcgcgacc
gtcgccgacgtcgtacgggagcaggacgtcaagcccccggcggtgatcgtcatcggcgag
gtcgtcgccgtcggaccacggacgtcgacgacattggcgtaa

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