Streptococcus lutetiensis: KE3_0611
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Entry
KE3_0611 CDS
T02775
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
slu
Streptococcus lutetiensis
Pathway
slu00300
Lysine biosynthesis
slu00550
Peptidoglycan biosynthesis
slu01100
Metabolic pathways
slu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KE3_0611
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KE3_0611
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KE3_0611
Enzymes [BR:
slu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KE3_0611
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
OapA_N
Motif
Other DBs
NCBI-ProteinID:
AGS05119
UniProt:
A0AB33AKX7
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All DBs
Position
556373..557737
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AA seq
454 aa
AA seq
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MKLTLYEVAKVVGAKNTISEFDDVPLRRIEFDSRKIEKGDLFLPLKGACNGHDFIETAFE
NGAVATFSERDVEGHPYILVDDCLEAFQALASYYLEKQRVDVIAVTGSNGKTTTKDMIAA
VLSTEYKTYKTQGNYNNEIGLPYTALHMPDDTEKIVLEMGQDHMGDIHLLSELAKPHIGV
VTLIGEAHLEFFGSREKIAKGKLQIVDGMDSDGILIAPADSIVDPYLPESQMVIRFGDGA
EIFVKDLQESKDSLTFTTNVIDRPITLPVPGKYNATNAMVAAYVGKLLAISDDDIVEALE
NIELTRNRTEWKKAANGADILSDVYNANPTAMRLILETFSKIPANEGGKKIAVLADMKEL
GEQSVELHRRMIMSLSPETLDTLIFYGEDIAELAQLASQMFPLGKVYYFKKTADEDQFED
MLKTVKTVLQPADQILLKGSNSMHLAKVVEALEN
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaactttatatgaagttgccaaagttgttggcgctaagaatacgatttcggag
tttgatgacgttcccctgcgacgaattgaatttgacagtcgtaagattgaaaaaggcgat
ttgttcttacctctaaagggtgcgtgtaatggacatgactttattgaaacagcttttgaa
aatggtgctgttgccactttttcagagcgtgatgttgaaggtcatccttatattttagtt
gacgattgtttagaagctttccaagccctagcaagttattatcttgaaaaacaacgtgtt
gatgtgattgcagtcacaggttcaaatggtaaaacaacaaccaaagacatgattgctgct
gtactttcaacagaatataaaacatacaaaacacaaggtaattacaataatgaaattggt
ttaccttatacagcacttcacatgccagatgatacagaaaaaattgtccttgaaatggga
caagaccacatgggtgatattcatctcttgtctgaattggctaaaccacacatcggtgtt
gtgactttgattggtgaagcgcacttggaattctttggcagccgtgagaaaattgctaaa
ggtaaacttcaaatcgttgatggtatggactcagatggtattttgattgcaccagctgac
tcaattgttgatccttacttaccagaaagtcaaatggtgattcgtttcggagacggtgct
gagatttttgtcaaagatttgcaagaaagcaaagattcgcttacttttacaaccaatgta
attgaccgtccaattacacttcctgttccaggaaaatacaatgctacaaatgccatggta
gcagcttatgttggtaagttattggcgatttcagatgatgatattgttgaagccttagaa
aacatcgaattaacacgtaaccgcacagaatggaaaaaagcggctaatggtgcagatatc
ctgtcagatgtctacaatgctaacccaacagcaatgcgtttgattttagaaacattctct
aaaattcctgctaatgaaggtggtaaaaaaattgctgtgcttgctgatatgaaagaatta
ggtgagcaatctgtcgaacttcacaggcgcatgattatgagtttgtcacctgaaacctta
gacactcttattttctatggtgaagacattgctgaactggcacaacttgctagtcaaatg
ttcccactaggtaaagtctattactttaagaaaacagctgatgaagatcaatttgaagac
atgctaaaaacggttaaaactgttttacaacctgctgaccaaatcttactgaaaggaagt
aattcaatgcatctcgctaaagttgtagaagctttggaaaactag
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