KEGG   Sander lucioperca (pikeperch): 116061112
Entry
116061112         CDS       T07345                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
sluc  Sander lucioperca (pikeperch)
Pathway
sluc04010  MAPK signaling pathway
sluc04012  ErbB signaling pathway
sluc04020  Calcium signaling pathway
sluc04510  Focal adhesion
sluc04520  Adherens junction
sluc04530  Tight junction
Brite
KEGG Orthology (KO) [BR:sluc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116061112 (erbb2)
   04012 ErbB signaling pathway
    116061112 (erbb2)
   04020 Calcium signaling pathway
    116061112 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116061112 (erbb2)
   04520 Adherens junction
    116061112 (erbb2)
   04530 Tight junction
    116061112 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sluc01001]
    116061112 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sluc04147]
    116061112 (erbb2)
   04090 CD molecules [BR:sluc04090]
    116061112 (erbb2)
Enzymes [BR:sluc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     116061112 (erbb2)
Protein kinases [BR:sluc01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   116061112 (erbb2)
Exosome [BR:sluc04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   116061112 (erbb2)
CD molecules [BR:sluc04090]
 Proteins
  116061112 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Tcell_CD4_C Haspin_kinase
Other DBs
NCBI-GeneID: 116061112
NCBI-ProteinID: XP_031170880
Ensembl: ENSSLUG00000011455
LinkDB
Position
22:13992740..14017129
AA seq 1296 aa
MEAARSLVFVGAVLLAVTGTLGREVCLGTDMKLDLPSSLENHYETLRLLYTGCQVVHGNL
EITHLHGDPDLSFLQGIVEVQGYVLVAHVSVSLLPLDNLRIIRGSQLYNSSYALAVLDNT
LGGQGLRTLRLRSLTEILLGGVYIWGNPQLCFPDPQNIIWRDTLDEQNIHARLHKLQLRA
PKCPSCSSVCGKSCWGETAQDCQTLTRIQCASGCQRCKGPLPNDCCHLQCAAGCTGPKDS
DCLACRHFNDSGVCKENCPPPTIYDPSTYQTKPNPNKKFNFGATCVKTCPYNYLAMEVAC
TLVCPRANQEVIVAHPDGNEMQKCEKCEGDCPKVCYGLGMDNLGVMDNHGIIMVTSTNVE
QFNKCKKIFGSLAFLPQSFASDPVSNTSGLTLEQLSAFKRLEEITGYLYIDAWPEEWTNL
SVFENLKVIRGRMLYKGVFSLAIQNLHIRSLGLRSLRSVSGGLVLLHNNSQLCYTSSLPW
DSLLHPTQGPHRIVSKNQDAQLCEEEGRVCHPLCEGGCWGPGPSQCASCKAFQRATECVE
QCDVYQGSLREYTDGSLCVACHSECRSLNGSASCHGPGAEHCSECRHFQDGEFCVDHCPS
GVKEDQQTVWKYSNATGHCLPCNTNCTLSCTVMDERGCPIDTRTGPGTTIAAAVGGVVLF
FILLALLVFYLKRQKKLRRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLR
VLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCR
LLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHR
DLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSD
VWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGERLPQPLICTIDVYMIMVKCWMIDPE
SRPRFKDLVNDFSAMARDPPRYVVIQNDEQMSMSSPVDSQFFRMLLEEEGNNMRELLDAE
EYLVPQPNHFPRTQGDGASRHQSYRQSRDQGLDVEPSVAGGPRSMYSSLSTLGRSQYPTL
PLGASTSNGVWVPQYPTLARSPSAGGQSDSVFLDGPPDELPPASPGRYCRDPTYSNGSQG
DLETDGPNGFHPSHHLNHSLPRRSHGYIHNHVLPEYVNQEIQDLRPGIPDRPSTLPRKGS
RVDRRLPNGLSSGHSVENPGYLVPVIVGAATSPAFDNPYYLDLVAKANAVARAAALDSPE
TLERDGGVPRHVNGFLTSTAENPEYLGLADTWSGYT
NT seq 3891 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagtttggtgtttgtcggggccgtgctgctcgcagtgacgggcacg
ttgggcagagaagtgtgcctgggtacagacatgaagctggacctgccctccagcctggaa
aatcactacgagaccctcagactgctctacactggctgccaggttgtccacggcaacctg
gagatcacacatcttcatggagaccctgacctctccttccttcaggggattgtggaggta
cagggctatgtacttgtagctcatgtgtcagtgagtctgttgccgttggacaaccttcga
atcataagaggcagccagctgtacaactccagctacgccctggctgtgctggataacact
ctgggcggacaggggctcaggacgctccggctccgtagcctcacagagatcctgttgggt
ggggtgtatatttgggggaacccccagctgtgcttcccagacccccagaacatcatttgg
agggacactttggacgagcagaacatccacgcccggctgcacaaactgcagcttcgggct
cctaaatgtccaagttgttcctctgtatgtgggaaaagctgctggggagaaactgcacag
gactgccagaccttgacccgtattcagtgtgcgtctggctgtcagcggtgtaaaggtccc
cttcccaatgactgctgtcacctgcagtgcgctgctggatgcacaggacccaaagactca
gactgtctggcgtgccgccacttcaacgacagtggtgtgtgtaaggagaactgtcctcca
ccgactatctacgatccctccacctatcagaccaaacccaacccaaacaagaagttcaac
tttggagccacttgcgtcaagacgtgtccttataactatctggctatggaagtggcttgt
actttggtttgtcccagagccaaccaggaagttatcgttgcccaccctgacggaaacgaa
atgcagaaatgtgaaaagtgtgaaggagactgtcccaaagtgtgttatggtctgggtatg
gacaacctcggcgtcatggacaaccatggcatcatcatggtaacatctactaatgtggag
cagttcaacaagtgtaagaagatttttggtagtctggccttcctccctcagagctttgca
agcgaccctgtgagcaacacatcgggtctgaccctcgagcagctgagtgccttcaaaaga
ctggaggagattacaggttatttgtacattgatgcctggccagaagagtggactaacctg
agtgtgtttgagaacctgaaggtgatcagaggcaggatgctctacaaaggggttttttct
ctggccatccagaatctacacatccggtcacttgggttgcgttcactacgcagcgtcagt
ggaggtttggtcctgttgcacaacaattcccagctgtgctacaccagttcactcccctgg
gatagtctcctccatcccacccagggaccccaccgcatcgtcagcaagaaccaggacgcc
caactctgtgaggaagagggccgtgtttgtcatcccctgtgcgaggggggctgctggggc
ccggggcccagccagtgtgcatcctgcaaggctttccaacgtgctactgagtgcgtggag
cagtgtgacgtatatcaggggtctctccgtgaatacacagatggatctttgtgtgttgcc
tgtcactcagaatgtcgatctctcaatggctctgcctcctgtcatggcccgggtgcagag
cattgttcagagtgtcgacacttccaggacggtgagttttgtgtggatcattgtcccagc
ggtgtgaaggaggatcagcaaactgtgtggaagtacagcaacgctacaggacactgtctc
ccctgcaacaccaactgcacgctgtcctgcactgtgatggatgagagaggctgccctatt
gacaccaggacaggaccgggtacaaccattgcagctgcagtgggtggggtggtgctcttc
ttcattctgctcgctctgctggtcttctacctgaagagacagaagaagctcaggaggaag
gagacaatgaggaggatactacaagaacatgagctcgtggagcctttgacacccagtggc
gcgtcacccaatcaggctcagatgcgtatcctgaaggagactgagttgaaaaaactcagg
gtgctgggtgcaggggcctttggcactgtttacaagggcgtgtgggctcctgatggggaa
aatgtgaaaataccagtggccatcaaggtgttacgagagaacacctcgccaaaggccaat
aaagagatccttgatgaggcctatgtgatggcaggagtggccagcccttacgtttgccgg
ctgctggggatttgtctgacctccacggtgcagctggtcactcagctgatgccgtacggc
tgcctcctcgactacgtcagggagaacaaggaccgcattggctcccagttcctcctcaac
tggtgtgtccagatcgccaaggggatgagttatctagaggaagtccggttggtccacaga
gatttggccgcccgcaatgttctggtcaagaacccaaaccatgtgaagatcactgacttt
ggtctggcccgtctgctcgatatagatgagactgaatatcacgctgatggagggaaggtg
ccgattaaatggatggcactagagtctattctgcacaggaagttcactcatcagagtgat
gtctggagctacggtgtgacggtctgggagctgatgacgtttggtgctaaaccctacgac
atgatcccagcaagagaaatcccagatgttttagagggaggagaacggcttccccagccc
ctcatctgcaccattgacgtctacatgatcatggtcaaatgttggatgattgacccagaa
agcagaccgaggttcaaagatctggtgaatgattttagcgccatggccagggatccacct
cgctatgtagtcattcagaacgacgagcagatgagcatgtccagccctgtggacagccag
tttttccgaatgcttctggaggaggaagggaacaacatgagggaactgctggatgctgag
gagtatctggtacctcagccaaaccacttccccaggactcagggagacggggcatccaga
caccagtcatacaggcagagcagagatcagggcttagatgttgaaccctccgtcgccggc
ggccctcggagcatgtactcctccctgagcactcttggccgcagccagtaccctacctta
cctttaggggccagcacctccaacggcgtatgggtccctcagtacccaactctggctcgc
agcccctcggccgggggccaatctgactcggtcttcctggacgggcctccagatgagctg
cccccagccagccccggacgctactgcagagaccccacctactccaacgggagccagggc
gacctggagacagacgggccaaacggctttcatccttctcatcaccttaatcactcactg
cccagacggagtcatgggtatattcataatcatgtcttgccagagtacgtcaaccaggag
attcaggatctcaggccggggatccccgatcggcccagcacgctgcctcgtaaaggctcc
agagtagaccgacgcctccctaacggcctgagctccggtcatagcgtagaaaacccggga
tacttggtccccgtaattgtcggggctgccacctctccagcctttgacaacccatattac
ctggacctcgtggccaaagccaacgctgtagccagggctgcagccttggacagccctgag
acactggagagagacggaggagtgcccaggcacgtgaacgggtttctgacctccacggca
gagaatccagagtatctgggactagcagacacctggagtggatatacttga

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