Streptomyces luomodiensis: PS467_29160
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Entry
PS467_29160 CDS
T10277
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sluo Streptomyces luomodiensis
Pathway
sluo00470
D-Amino acid metabolism
sluo00550
Peptidoglycan biosynthesis
sluo01100
Metabolic pathways
sluo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sluo00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
PS467_29160
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PS467_29160
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PS467_29160
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sluo01011
]
PS467_29160
Enzymes [BR:
sluo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
PS467_29160
Peptidoglycan biosynthesis and degradation proteins [BR:
sluo01011
]
Precursor biosynthesis
Amino acid ligase
PS467_29160
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
WNE99105
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Position
6887341..6888513
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AA seq
390 aa
AA seq
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MSSQTPSPGPVPASSGGERRKPRVAVVFGGRSSEHAISVVTAGAVLRAIDREKYDVLPIG
ITVDGRWALTADEPERMAIAGRELPSVERLAESSEGSVVLPVDPGNREVVYSEPGAVPKA
LGDVDVVFPMLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGMDKEYMKRVFVSFGLPV
GPYEVIRPRAWEQDPSAARRRIVEFAEEHGWPLFVKPARAGSSFGISKVENAADLDAAIE
EARRHDPKVIVEALLRGREIECGVLEYEDGPRASVPAEIPPVSSHAFYDFEAKYIDSADG
IVPAPLTEEQTRRVQELAVAAFDAASCEGLVRADFFLLDSGEFVINEINTMPGFTPISMY
PRMWQESGVSYPELVDRLLQAALRRSTGLR
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgagcagccagaccccttccccaggccctgttccggcttcctccggaggtgagcggcgg
aagccgcgcgtcgccgtcgtcttcggcggccgcagctccgagcacgccatctcggtggtc
accgccggcgccgtgctgcgcgccatcgaccgcgagaagtacgacgtgctgccgatcggc
atcaccgtggacggccgttgggcgctgaccgccgacgagcccgagcggatggccatcgcg
ggccgcgagctgcccagcgtcgaacggctcgccgagtccagcgagggttcggtcgtcctc
ccggtcgacccggggaaccgcgaggtcgtctacagcgagccgggcgcggtgcccaaggcg
ctgggcgacgtcgacgtcgtcttccccatgctgcacggcccgtacggtgaggacggcacc
ctccaggggttgctggagctgtccggggtgccctatgtgggcgccggggtgctcgcctcc
gccgtgggcatggacaaggagtacatgaagcgggtgttcgtctccttcgggctgcccgtc
ggcccgtacgaggtgatccgcccccgggcctgggagcaggatccttccgccgcccgtcgc
aggatcgtggagttcgccgaggagcacggctggccgctcttcgtgaagcccgcgcgcgcc
ggctcgtccttcggcatcagcaaggtcgagaacgcggcggacctggacgcggccatcgag
gaggcccggcgccacgacccgaaggtcatcgtggaggcgctgctgcgcggccgcgagatc
gaatgcggggtgctggagtacgaggacgggccgcgggccagcgtgcccgccgagatcccg
ccggtctcctcccacgccttctacgacttcgaggcgaagtacatcgactccgcggacggc
atcgtgcccgcgccgctcaccgaggagcagacccggcgggtccaggagctcgcggtggcc
gccttcgacgcggcgtcctgcgaggggctggtccgggccgacttcttcctgctggacagc
ggcgagttcgtgatcaacgagatcaacacgatgcccggcttcaccccgatctcgatgtac
ccgcgcatgtggcaggagagcggtgtgagctatcccgagctggtggaccggctgctccag
gccgcgctgcgccgctcgacgggactgcgctag
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