Streptomyces luomodiensis: PS467_39435
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Entry
PS467_39435 CDS
T10277
Symbol
fkbA
Name
(GenBank) tacrolimus type I polyketide synthase FkbA
KO
K16377
polyketide synthase FkbA
Organism
sluo Streptomyces luomodiensis
Pathway
sluo01052
Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:
sluo00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
PS467_39435 (fkbA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
sluo01008
]
PS467_39435 (fkbA)
Polyketide biosynthesis proteins [BR:
sluo01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Immunomycin PKS
PS467_39435 (fkbA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
Ketoacyl-synt_C
KR
KAsynt_C_assoc
PKS_DH_N
PP-binding
PS-DH
CurL-like_PKS_C
ADH_zinc_N_2
Thiolase_N
ADH_N
RhiE-like_linker
ADH_zinc_N
DUF7080
adh_short
ACP_syn_III
Docking
2-Hacid_dh_C
Motif
Other DBs
NCBI-ProteinID:
WNF00985
LinkDB
All DBs
Position
complement(9365566..9384756)
Genome browser
AA seq
6396 aa
AA seq
DB search
MPEQDKTVEYLRWATAELQKTRAELAAHSEPLAIVGMACRLPGGVGSPEDLWQLLESGGD
GITAFPTDRGWETTADGRGGFLTGAAGFDAAFFGISPREALAMDPQQRLALETSWEAFEH
AGIDPQTLRGSDTGVFLGAFFQGYGIGADFDGYGTTSIHTSVLSGRLAYFYGLEGPAVTV
DTACSSSLVALHQAGQSLRSGECSLALVGGVTVMASPAGFADFSEQGGLAPDARCKAFAE
AADGTGFAEGSGVLIVEKLSDAERNGHRVLAVVRGSAVNQDGASNGLSAPNGPSQERVIR
QALANAGLTPADVDAVEAHGTGTRLGDPIEAQAVLATYGQGRDTPLLLGSLKSNIGHTQA
AAGVAGVIKMVLAMRHGTLPRTLHVDTPSSHVDWTAGAVELLTDARPWPETDRPRRAGVS
SFGVSGTNAHIILESHPRPAPEPDTAPDTGPLPLLLSARTPQALDAQVHRLRAFLDDNPG
ADRVAVAQTLARRTQFEHRAVLLGDTLITVSPNAGRGPVVFVYSGQSTLHPHTGRQLAAT
YPVFADAWREALDHLDPAQGPATHFAHQTALTALLRSWGITPHAVIGHSLGEITAAHAAG
VLSLRDAGALLTTRTRLMDQLPAGGAMVTVLTSEEKARQVLRPGVEIAAVNGPHSLVLSG
DEEAVLEAARQLGIHHRLPTRHAGHSERMQPLVAPLLELARTLTYHQPHTAIPGDPTTAE
YWAHQVRDQVRFQAHTEQYPGATFLEIGPNQDLSPLVDGVAAQTGTPDEVRALHTALAQL
HVRGVAIDWTLVLGGDRAPVTLPTYPFQHKDYWLRPTSRADVTGAGQEQVAHPLLGAAVA
LPGTGGVVLTGRLSLASHPWLGEHAVDGTVLLPGAAFLELAARAGDEVGCDLLHELVIET
PLVLPATGGVAVSVEVAEPDDTGRRAVTVHARADGSGLWTRHAGGFLGTAPAPAPAAGAD
PAPWPPTEAGPVDVADVYDRFEDIGYSYGPGFRGLRAAWRAGDTVYAEVALPDEQNADAA
RFTLHPALLDAAFQAGALAALDAPGGAARLPFSFQDVHIHAAGATRLRVTVGRDGERSTV
RMTGPDGQLVAVVGSVLSRPYAEGSGDGLLRPVWTELPMPVPSADDPRVEVLGADPGDGD
VPAATRELTARVLGALQHHLSAAEDTTLVVRTGTGPAAAAAAGLVRSAQAENPGRVVLVE
ASPDTPVELLAACAALDEPQLAVRDGVLFAPRLVRVSDPAHGPLSLPDGDWLLTRSASGT
LHDVALTADDTPRRALEAGEVRIDVRAAGLNFRDVLIALGTYTGATAMGGEAAGVVVETG
PGVDDLSPGDRVFGLTRGGIGPTAVTDRRWLARIPDGWSFTTAASVPIVFATAWYGLVDL
GTLRAGEKVLVHAATGGVGMAAAQIARHLGAELYATASTGKQHVLRAAGLPDTHIADSRT
TAFRTAFPRMDVVLNALTGEFIDASLDLLDADGRFVEMGRTELRDPAAIVPAYLPFDLLD
AGADRIGEILGELLRLFDAGALEPLPVRAWDVRQARDALGWMSRARHIGKNVLTLPRPLD
PEGAVVITGGSGTLAGILARHLRERHVYLLSRTAPPEGTPGVHLPCDVGDRDQLAAALGR
VDRPITAVVHLAGALDDGTVASLTPERFDTVLRPKADGAWYLHELTKEQDLAAFVLYSSA
AGVLGNAGQGNYVAANAFLDALAELRHGSGLPALSIAWGLWEDVSGLTAALGEADRDRMR
RSGFRAITAQQGMHLYEAAGRTGSPVVVAAALDDAPDVPLLRGLRRTTVRRAAVRERSSA
DRLAALTGDELAEALLTLVRESTAAVLGHVGGEDIPATAAFKDLGIDSLTAVQLRNALTE
ATGVRLNATAVFDFPTPHVLAGKLGDELTGTRAPVVPRTAATAGAHDEPLAIVGMACRLP
GGVASPEELWHLVASGTDAITEFPTDRGWDVDAIYDPDPDAIGKTFVRHGGFLTGATGFD
AAFFGISPREALAMDPQQRVLLETSWEAFESAGITPDSTRGSDTGVFVGAFSYGYGTGAD
TDGFGATGSQTSVLSGRLSYFYGLEGPAVTVDTACSSSLVALHQAGQSLRSGECSLALVG
GVTVMASPGGFVEFSRQRGLAPDGRAKAFGAGADGTSFAEGAGVLIVERLSDAERNGHTV
LAVVRGSAVNQDGASNGLSAPNGPSQERVIRQALANAGLTPADVDAVEAHGTGTRLGDPI
EAQAVLATYGQERATPLLLGSLKSNIGHAQAASGVAGIIKMVQALRHGELPPTLHADEPS
PHVDWTAGAVELLTSARPWPETDRPRRAAVSSFGVSGTNAHVILEAGPVTETPAASPAGD
LPLLVSARSPEALDEQIRRLRGYLDTTPDVDRVAVAQTLARRTHFAHRAVLLGDTVITTP
PADRPDELVFVYSGQGTQHPAMGEQLAAAHPVFADAWHEALRRLDDPDPHDPTHSQHVLF
AHQAAFTALLRSWGITPHAVIGHSLGEITAAHAAGILSLDDACTLITTRARLMHTLPPPG
AMVTVLTSEEKARQALRPGVEIAAVNGPHSLVLSGDEDAVLTVAGQLGIHHRLPAPHAGH
SAHMEPVAAELLATTRGLRYNPPHTSIPNDPTTAEYWAEQVRKPVLFHAHTQQYPDAVFV
EIGPAQDLSPLVDGIPLQNGTADEVHALHTALAHLYARGATLDWPRILGGGSRHDADVPA
YAFQRRHYWIESARPAASDAGHPVLGSGIALAGSPGRVFTGSVPTGADRAVFVAELALAA
ADAVDCATVERLAIASVPSRPGHGRTTVQTWVDEPADDGRRRFTVHTRTGDAPWTLHAEG
VLRPHGTALPDAAGTEWPPPGAVPADGLPGVWRRGDQVFAEADVDGPDGFVVHPDLLDAV
FSAVGDGSRQPAGWRDLTVHASDATVLRACLTRRTDGAMGLAAFDGAGLPVLTAEAVTLR
EVASTSGSEESDGLLRLEWLAVAEAVYDGDLPEGHVLITAAHPDDPEDIPTRAHTRATRV
LTALQHHLTTTDHTLIVHTTTDPAGATVTGLTRTAQNEHPHRIRLIETDHPHTPLPLAQL
ATLDHPHLRLTHHTLHHPHLTPHHTTTPPTTTPLNPEHAIIITGGSGTLAGILARHLNHP
HTYLLSRTPPPDTTPGTHLPCDVGDPHQLATTLAHIPQPLTAIFHTAATLDDGIIDALTP
DRLTTVLHPKANAAWHLHHLTQNQPLTHFVLYSSAAAVLGSPGQGNYAAANAFLDALATH
RHTLGQPATSIAWGMWHTTSTLTGQLSDADRDRIRRGGFLPITDDEGMRLYEAAVGSGED
FVMAAAMDPAQPMTGSVPPILSGLRRSARRVARAGQTFAQRLAELPDADRGAALVTLVSD
ATAAVLGHADASEIAPTTTFKDLGIDSLTAIELRNRLAEATGLRLSATLVFDHPTPRVLA
AKLRTDLFGTAVPTPARTARTHHDEPLAIVGMACRLPGGVASPEDLWQLVASGTDAITEF
PTDRGWDIDRLFDPDPDAPGKTYVRHGGFLAEAAGFDAAFFGISPREARAMDPQQRVILE
TSWEAFENAGIVPDTLRGSDTGVFMGAFSHGYGAGVDLGGFGATATQNSVLSGRLSYFFG
MEGPAVTVDTACSSSLVALHQAAQALRTGECSLALAGGVTVMPTPLGYVEFCRQRGLAPD
GRAKAFAEGADGTSFSEGAGVLVLERLSDAERNGHTVLAVVRSSAVNQDGASNGISAPNG
PSQQRVIRQALDKAGLAPADVDVVEAHGTGTPLGDPIEAQAIIATYGQDRDTPLYLGSVK
SNIGHTQTTAGVAGVIKMVMAMRHGIAPKTLHVDEPSSHVDWTEGAVELLTDARPWPDAG
RPRRAGVSSLGISGTNAHVILEGVPGPSVVESVVDGLVPLPVSARSEVSLRGQVERLEGY
LRGGGVDVAAVAQGLVRERAVFGHRTVLLGDARVTGVAVDQPRTVFVFPGQGAQWVGMGV
ELMARSAVFAARMEECAQALLPHTGWDVREMLSRPDVAERVEVVQPASWAVAVSLAALWQ
AHGVVPDAVIGHSQGEIAAACVAGALSLEDAARVVALRSQVIAARLAGRGAMASVALPAG
EVGLVEGVWIAARNGPSSTVVAGEPSAVEEVVARYEADGVRVRRIAVDYASHTPHVEAIE
DELAEVLEGISGGTGSVAWWSTVDSAWVTEPVDEGYWYRNLRRPVALDAAVAELDGSVFV
ECSAHPVLLPAMEQAHTVASLRTGDGGWERWLTALAQAWTLGAAVDWDTVVEPVPGRLLD
LPTYAFEHRRYWLEAAGATDLSAAGLTGAAHPMLAAVTALPADDGGVVLTGRISLRTHPW
LADHAVRGTVLLPGTAFVELVIRAGDETGCGVVDELVIETPLVVPVTEAVDVSVTVEGAD
EAGRRPVTVHARTEGTGSWTRHASGTLTPDTPNASGVVGAEPFSQWPPATAAAVDTSEFY
SRLDALGYRFGPMFRGMRAAWRDGDTVYAEVALPEDRAADADGFGMHPALLDAALQSGSL
LMLESDGEQSVQLPFSWHGVRFHATGATMLRVAVVPGPDGLRLHAADSGNRPVATIDALV
TRSPEADLAPADPMLRVGWAPVPVPAGAGPSDADVLTLRGDDADPLGETRDLTTRVLDAL
LRADRPVIFQVTGGLAAKAAAGLVRTAQNEQPGRFFLVETDPSEVLDGAKRDAIAALGEP
HVRLRDGLFEAARLMRATPSLTLPDTGSWQLRPSATGSLDDLAVVRTDAPDRPLAAGEVR
IAVRAAGLNFRDVTVALGVVADERPLGSEAAGVVLETGPGVHDLAPGDRVLGMLAGAFGP
VAITDRRLLGRMPDGWTFPQAASVMTAFATAWYGLVDLAGLRPGEKVLIHAAATGVGAAA
VQIARHLGAEVYATTSAAKRHLVDLDGAHLADSRSTAFADAFPPVDVVLNSLTGELLDAS
VGLLAPGGRFIEMGKTDIRHAVQQPFDLMDAGPDRMQRIIVELLGLFARDVLHPLPVHAW
DVRQAREAFGWMSSGRHTGKLVLTIPRPLDPEGAVVITGGSGTLAGILARHLNHPHTYLL
SRTPPPDTTPGTHLPCDVGDPHQLATTLARIPQPLTAVFHTAGTLDDALLDNLTPDRIDT
VLKPKADAAWHLHRLTRDTDLAAFVVYSAVAGLMGSPGQGNYVAANAFLDALAEHRRTQG
LPAQSLAWGMWADVSALTAKLTDADRQRIRRSGFPPLSAADGMRLFDAATRTPEPVVVAT
TVDLTQLDGPVAPLLRGLAAHRAGPARTVARNAGEEPLAVRLAGRTAAEQRRIMQEVVLR
HAAAVLAYGLGDRVAADRPFRELGFDSLTAVDLRNRLAAETGLRLPTTLVFSHPTAEALT
AHLLELIDAPTARIAGESLPAVTAAPVAAARDQDEPIAIVAMACRLPGGVTSPEDLWRLV
ESGTDAITTPPDDRGWDVDALYDADPDAAGKAYNLRGGYLDGAAEFDAAFFDISPREALG
MDPQQRLLLETAWEAIERGRISPASLRGREVGVYVGAAAQGYGLGAEDTEGNAITGGSTS
LLSGRLAYVLGLEGPAVTVDTACSSSLVALHLACQGLRLGECELALAGGVSVLSSPAAFV
EFSRQRGLAADGRCKSFGAGADGTTWSEGVGVLVLERLSDAERLGHTVLAVVRGSAVTSD
GASNGLTAPNGLSQQRVIRKALAAAGLTGADVDVVEGHGTGTRLGDPVEADALLATYGQN
RPAPVWLGSLKSNIGHATAAAGVAGVIKMVQAIGAGTMPRTLHVEEPSPAVDWSTGQVSL
LGSNRPWPDDARPRRAAVSAFGLSGTNAHVILEQHRPAPVASQPPRPPREESQPLPWVLS
ARTPDALRAQAARLRDHLAVAPDADPLDIGYALATSRAQFAHRAAVVATTPDGFRAALDG
LADGAEAPGVVTGTAQERRVAFLFDGQGAQRAGMGRDLHRRFPVFAAAWDEVSDAFGKHL
KHSPTDVYHGEHGALAHDTLYAQAGLFTLEVALLRLLEHWGVRPDVLVGHSVGEVTAAYA
AGVLTLADATELIVARGRALRALPPGAMIAVDGSPAEVGARTDLDIAAVNGPSAVVLAGS
PDDVAAFEREWSAAGRRTKRLDVGHAFHSRHVDGALDGFRTVLESLAFGAARLPVVSTTT
GRDAADDLITPAHWLRHARRTVLFSDAVRELADRGVTTFVAVGPSGSLASAAAESAGEDA
GTYHAVLRARTSEETAALTALAELHAHGVPVDLAAVLAGGRPVDLPVYAFQHRSYWLAPA
VAGAPATVADTGGPAESEPEDLTVAEIVRRRTAALLGVTDPADVDAEATFFALGFDSLAV
QRLRNQLASATGLDLPAAVLFDHDTPAALTAFLQDRIEAGQDRIEAGEDDDAPTVLSLLE
EMESLDAADIAATPAPERAAIADLLDKLAHTWKDYR
NT seq
19191 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagcaggacaagacagtcgagtaccttcgctgggcgaccgcggaactccagaag
acccgtgcggaactcgccgcgcacagcgagccgttggcgatcgtggggatggcctgccgg
ctgcccggcggggtcgggtcgccggaggacctgtggcagttgctggagtccggtggtgac
ggcatcaccgcgttccccacggaccggggctgggagaccaccgccgacggtcgcggcggc
ttcctcaccggggcggccggcttcgacgcggcgttcttcgggatcagcccgcgtgaggca
ctggcgatggacccgcagcagcgcctggccctggagacctcgtgggaggcgttcgagcac
gcgggcatcgatccgcagacactgcggggcagtgacacgggggtgttcctcggcgcgttc
ttccaggggtacggcatcggcgccgacttcgacggttacggcaccacgagcattcacacc
agcgtgctctccggccgcctcgcgtacttctacggtctggagggtccggcggtcacggtc
gacacggcgtgttcgtcgtcgctggtggcgctgcaccaggccgggcagtcactgcgctcc
ggcgaatgctcgctcgcgctggtcggcggcgtcacggtgatggcatcgccggcggggttc
gcggacttctccgagcagggcggcctggcccccgacgcgcgctgcaaggcgttcgcggaa
gcggctgacggcaccggtttcgccgaggggtccggcgtcctgatcgtcgagaagctctcc
gacgccgagcgcaacggccaccgcgtgctggcggtcgtccggggttccgccgtcaaccag
gacggtgcctccaacgggctgtcggcgccgaacgggccgtcgcaggagcgggtgatccgg
caggccctggccaacgccgggctcaccccggcggacgtggacgccgtcgaggcccacggc
accggcaccaggctgggcgaccccatcgaggcacaggcggtgctggccacctacgggcag
gggcgcgacacccccctgctgctgggctcgctgaagtccaacatcggccacacccaggcc
gccgcgggcgtcgccggtgtcatcaagatggtcctcgccatgcggcacggcaccctgccc
cgcaccctgcacgtggacacgccgtcctcgcacgtcgactggacggccggagccgtcgaa
ctcctcaccgacgcccgcccctggcccgaaaccgaccgcccacggcgcgccggtgtgtcc
tccttcggcgtcagcggcaccaacgcccacatcatcctcgaaagccacccccgaccggcc
cccgaacccgacaccgcacccgacaccggaccgctgccactgctgctctcggcacgcacc
ccgcaggcactcgacgcacaggtacaccgcctgcgcgcgttcctcgacgacaaccccggc
gcggaccgggtcgccgtcgcgcagacactcgcccggcgcacccagttcgagcaccgcgcc
gtgctgctcggcgacacgctcatcaccgtgagcccgaacgccggccgcggaccggtggtc
ttcgtctactcggggcaaagcacgctgcacccgcacaccgggcggcaactcgcggccacc
taccccgtgttcgccgacgcatggcgcgaggccctcgaccacctcgaccccgcccagggc
ccggccacgcacttcgcccaccagaccgcgctcaccgcgctcctgcggtcctggggcatc
accccgcacgcggtcatcggccactccctcggtgagatcaccgccgcgcacgccgccggt
gtcctgtccctgagggacgcgggcgcgctcctgaccacccgcacccgcctgatggaccaa
cttccggcgggcggcgcgatggtcaccgtcctgaccagcgaggaaaaggcacgccaggtg
ctgcggccgggggtggagatcgccgccgtcaacggcccccactccctcgtgctgtccggg
gacgaggaggccgtactcgaagccgcccggcagctcggcatccaccaccgcctgccgacc
cgccacgccggccactccgagcgcatgcagccgctcgtcgcccccctcctcgaacttgcc
cggaccctgacgtaccaccagccccacaccgccatccccggcgaccccaccaccgccgaa
tactgggcgcaccaggtccgcgaccaagtacgtttccaggcgcacaccgagcagtacccg
ggcgcgacgttcctcgagatcggccccaaccaggacctctcgccgctcgtcgacggcgtt
gccgcccagaccggtacgcccgacgaggtgcgggcgctgcacaccgcgctcgcgcagctc
cacgtccgcggcgtcgcgatcgactggacgctcgtcctcggcggggaccgcgcgcccgtc
acgctgcccacgtatccgttccagcacaaggactactggctgcggcccacctcccgggcc
gatgtgaccggcgcgggacaggagcaggtggcgcacccgctgctcggcgccgcggtcgcg
ctgcccggcacgggcggagtcgtcctgaccggccgcctgtcgctggcctcccatccgtgg
ctcggcgagcacgcggtcgacggcaccgtgctcctgcccggcgcggccttcctcgaactc
gcggcgcgcgccggcgacgaggtcggctgcgacctgctgcacgaactcgtcatcgagacg
ccgctcgtgctgcccgcgaccggcggtgtggcggtctccgtcgaggtcgccgaacccgac
gacacggggcggcgggcggtcaccgtccacgcgcgggccgacggctcgggcctgtggacc
cgccacgccggcggattcctcggcacggcaccggcaccggcaccggccgccggggcggac
ccggcaccctggccgcccacggaagccggaccggtcgacgtcgccgacgtctacgaccgg
ttcgaggacatcgggtactcctacggaccgggcttccgggggctgcgggccgcctggcgc
gccggcgacaccgtgtacgccgaggtcgcgctccccgacgagcagaacgccgacgccgcc
cgtttcacgctgcaccccgcgctgctcgacgccgcgttccaggccggcgcgctggccgcg
ctcgacgcacccggcggggcggcccgactgccgttctcgttccaggacgtccacatccac
gcggccggggcgacgcggctgcgggtcacggtcggccgcgacggcgagcgcagcaccgtc
cgcatgaccggcccggacgggcagctggtggccgtggtcggttccgtgctgtcgcgcccg
tacgcggaaggctccggtgacggcctgctgcgcccggtctggaccgagctgccgatgccc
gtcccgtccgcggacgacccgcgcgtggaggtcctcggcgccgacccgggcgacggcgac
gttccggcggccacccgagagctgaccgcccgcgtcctcggcgcgctccagcaccacctg
tccgccgccgaggacaccaccttggtggtacggaccggcaccggcccggccgctgccgcc
gccgcgggcctggtccgctcggcgcaggcggagaaccccggccgcgtcgtgctcgtcgag
gcgtccccggacaccccggtggagctgctcgccgcgtgcgccgcgctggacgaaccgcaa
ctggccgtccgggacggcgtgctcttcgcgccgcggctggtccgggtgtccgaccccgcg
cacggcccgctgtccctgccggacggcgactggctgctcacccggtccgcctccggcacg
ttgcacgacgtcgcgctcaccgccgacgacacgccccggcgggcgctcgaagccggcgag
gtccgcatcgacgtccgcgcggccggactgaacttccgcgatgtgctgatcgcgctcggg
acgtacaccggggccacggccatgggcggcgaggccgcgggcgtcgtggtggagaccggg
cccggcgtggacgacctgtcccccggcgaccgggtgttcggcctgacccggggcggcatc
ggcccgacggccgtcaccgaccggcgctggctggcccggatccccgacggctggagcttc
accacggcggcgtccgtccccatcgtgttcgcgaccgcgtggtacggcctggtcgacctc
ggcacgctgcgcgccggcgagaaggtcctcgtccacgcggccaccggcggtgtcggcatg
gccgccgcacagatcgcccgccacctgggcgccgagctctacgccaccgccagtaccggc
aagcagcacgtcctgcgcgccgccgggctgcccgacacgcacatcgccgactctcggacg
accgcgttccggaccgctttcccgcgcatggacgtcgtcctgaacgcgctgaccggcgag
ttcatcgacgcgtcgctcgacctgctggacgccgacggccggttcgtcgagatgggccgc
accgagctgcgcgacccggccgcgatcgtccccgcctacctgccgttcgacctgctggac
gcgggcgccgaccgcatcggcgagatcctgggcgaactgctccggctgttcgacgcgggc
gcgctggagccgctgccggtccgtgcctgggacgtccggcaggcacgcgacgcgctcggc
tggatgagccgcgcccgtcacatcggcaagaacgtcctgacgctgccccggccgctcgac
ccggagggcgccgtcgtcatcaccggcggctccggcacgctcgccggcatcctcgcccgc
cacctgcgcgaacggcatgtctacctgctgtcccggacggcaccgcccgaggggacgccc
ggcgtccacctgccctgcgacgtcggtgaccgggaccagctggcggcggcccttgggcgg
gtggaccggccgatcaccgccgtggtgcacctcgccggtgcgctggacgacggcaccgtc
gcatcgctcacccccgagcgtttcgacacggtgttgcgcccgaaggccgacggcgcctgg
tacctgcacgagctgacgaaggagcaggacctcgccgcgttcgtgctctactcgtcggcc
gccggcgtgctcggcaacgccggccagggcaactacgtcgccgcgaacgcgttcctcgac
gcgctcgccgagctgcgccacggttccgggctgccggccctctccatcgcctgggggctc
tgggaggacgtgagcgggctcaccgcggcgctcggcgaagccgaccgggaccggatgcgg
cgcagcggtttccgggccatcaccgcgcaacagggcatgcacctgtacgaggcggccggc
cgcaccggaagtcccgtggtggtcgcggcggcgctcgacgacgcgccggacgtgccgctg
ctgcgcggcctgcggcggacgaccgtccggcgggccgccgtccgggagcgttcgtccgcc
gaccggctcgccgcgctgaccggcgacgagctcgccgaagcgctgttgacgctcgtccgg
gagagcaccgccgccgtgctcggccacgtgggtggcgaggacatccccgcgacggcggcg
ttcaaggacctcggcatcgactcgctcaccgcggtccagctgcgcaacgccctcaccgag
gcgaccggtgtgcggctgaacgccacggcggtcttcgacttcccgaccccacacgtgctc
gccgggaagctcggcgacgaactgaccggcacccgcgcgcccgtcgtgccccggaccgcg
gccacggccggtgcgcacgacgagccgctggcgatcgtggggatggcctgccggctgccc
ggcggggtggcgtcacccgaggagctgtggcacctcgtggcgtccggcaccgacgccatc
acggagttcccgacggaccgcggctgggacgtcgacgcgatctacgacccggaccccgac
gcgatcggcaagaccttcgtccggcacggcggcttcctcaccggcgcgacaggcttcgac
gcggcgttcttcggcatcagcccgcgcgaggccctcgcgatggacccgcagcaacgggtg
ctcctggagacgtcgtgggaggcgttcgaaagcgccggcatcaccccggactcgacccgc
ggcagcgacaccggcgtgttcgtcggcgccttctcctacggttacggcaccggtgcggac
accgacggcttcggcgcgaccggctcgcagaccagtgtgctctccggccggctgtcgtac
ttctacggtctggagggcccggcggtcaccgtcgacacggcgtgttcgtcgtcgctggtg
gcgctgcaccaggccggacagtcgctgcgctccggcgaatgctcgctcgccctggtcggc
ggcgtcacggtcatggcgtctcccggcggcttcgtggagttctcccggcagcgcggcctc
gcgccggacggccgggcgaaggcgttcggcgcgggtgcggacggcacgagcttcgccgag
ggtgccggtgtgctgatcgtcgagaggctctccgacgccgaacgcaacggccacaccgtc
ctggcggtcgtccggggttcggcggtcaaccaggacggtgcctccaacgggctgtcggcg
ccgaacgggccctcgcaggaacgggtgatccggcaggccctggccaacgccggactcacc
ccggcggacgtggacgccgtcgaggcccacggcaccggcaccaggctgggcgaccccatc
gaggcgcaggcggtactggccacctacggacaggagcgcgccacccccctgctgctgggc
tcgctgaagtccaacatcggccacgcccaggccgcgtccggcgtcgccggcatcatcaag
atggtgcaggccctccggcacggggagctgccgccgacgctgcacgccgacgagccgtcg
ccgcacgtcgactggacggccggcgccgtcgaactgctgacgtcggcccggccgtggccc
gagaccgaccggccacggcgtgccgccgtctcctcgttcggggtgagcggcaccaacgcc
cacgtcatcctggaggccggaccggtaacggagacgcccgcggcatcgccggccggtgac
cttcccctgctggtgtcggcacgctcaccggaagcgctcgacgagcagatccgccgactg
cgcggctacctggacaccaccccggacgtcgaccgggtggccgtggcacagacgctggcc
cggcgcacgcacttcgcccaccgcgccgtgctgctcggtgacaccgtcatcaccacaccc
cccgcggaccggcccgacgaactcgtcttcgtctactccggccagggcacccagcatccc
gcgatgggcgagcagctcgccgccgcccatccggtgttcgccgacgcctggcatgaagcg
ctccgccgccttgacgaccccgacccccacgaccccacgcacagccagcatgtgctcttc
gcccaccaggcggcgttcaccgccctcctgcggtcctggggcatcaccccgcacgcggtc
atcggccactcgctgggcgagatcaccgcggcgcacgccgccggcatcctgtcgctggac
gacgcgtgcaccctgatcaccacgcgcgcccgcctcatgcacacgctcccgccacccggt
gccatggtcaccgtcctgaccagcgaagagaaggcacgccaggcgttgcggccgggcgtg
gagatcgccgccgtcaacgggccccactccctcgtgctgtccggggacgaggacgccgtg
ctcaccgtcgccgggcagctcggcatccaccaccgcctgcccgccccgcacgccgggcac
tccgcgcacatggagcccgtggccgccgagctgctcgccaccacccgcgggctccgctac
aaccctccccacacctccattccgaacgaccccaccaccgccgagtactgggccgagcag
gtccgcaagcccgtgctgttccacgcccacacgcagcagtacccggacgccgtgttcgtg
gagatcggccccgcccaggacctctccccgctcgtcgacgggattccgctgcagaacggc
accgcggacgaggtgcacgcgctgcacaccgcgctcgcgcacctctacgcgcgcggtgcc
acgctcgactggccccgcatcctcgggggtgggtcacggcacgacgcggatgtgcccgcg
tacgcgttccaacggcggcactactggatcgagtcggcgcgcccggccgcatccgacgcg
ggccaccccgtgctgggctccggtatcgccctcgccgggtcgccgggccgggtgttcacg
ggttccgtgccgaccggtgcggaccgcgcggtgttcgtcgccgagctggcgctggccgcc
gcggacgcggtcgactgcgccacggtcgagcggctcgccatcgcctccgtgcccagccgg
ccgggccatggccggacgaccgtacagacctgggtcgacgagccggcggacgacggccgg
cgccggttcaccgtgcacacccgcaccggcgacgccccgtggacgctgcacgccgagggg
gtgctgcgcccccatggcacggccctgcccgatgcggccggcaccgagtggcccccaccg
ggcgcggtgcccgcggacgggctgccgggtgtgtggcgccggggggaccaggtcttcgcc
gaggccgatgtggacggaccggacggtttcgtggtgcaccccgacctgctcgacgcggtc
ttctccgcggtcggcgacggaagccgccagccggccggatggcgcgacctgacggtgcac
gcgtcggacgccaccgtactgcgcgcctgcctcacccggcgcaccgacggagccatggga
ctcgccgccttcgacggcgccggcctgccggtgctcaccgcggaggcggtgacgctgcgg
gaggtggcgtcaacgtccggttccgaggagtcggacggcctgctccggttggagtggctc
gcggtcgccgaggcggtctacgacggtgacctgcccgagggacatgtcctgatcaccgcc
gcccaccccgacgaccccgaggacatacccacccgcgcccacacccgcgccacccgcgtc
ctgaccgccctgcaacaccacctcaccaccaccgaccacaccctcatcgtccacaccacc
accgaccccgccggcgccaccgtcaccggcctcacccgcaccgcccagaacgaacacccc
caccgcatccgcctcatcgaaaccgaccacccccacacccccctccccctggcccaactc
gccaccctcgaccacccccacctccgcctcacccaccacaccctccaccacccccacctc
accccccaccacaccaccaccccacccaccaccacccccctcaaccccgaacacgccatc
atcatcaccggcggctccggcaccctcgccggcatcctcgcccgccacctgaaccacccc
cacacctacctcctctcccgcaccccaccccccgacaccacccccggcacccacctcccc
tgcgacgtcggcgacccccaccaactcgccaccaccctcgcccacatcccccaacccctc
accgccatcttccacaccgccgccaccctcgacgacggcatcatcgacgccctcaccccc
gaccgcctcaccaccgtcctccaccccaaagccaacgccgcctggcacctgcaccacctc
acccaaaaccaacccctcacccacttcgtcctctactccagcgccgccgccgtcctcggc
agccccggacaaggaaactacgccgccgccaacgccttcctcgacgccctcgccacccac
cgccacaccctcggccaacccgccacctccatcgcctggggcatgtggcacaccaccagc
accctcaccggacaactcagcgacgccgaccgggaccgcatccgccgcggcggtttcctc
ccgatcacggacgacgagggcatgcgcctgtacgaggcggcggtcggctccggcgaggac
ttcgtcatggccgccgcgatggacccggcacagccgatgaccggctccgtaccgcccatc
ctgagcggcctgcgcaggagcgcgcggcgcgtcgcccgtgccgggcagacgttcgcccag
cggctcgccgagctgcccgacgccgaccgcggcgcggcgctggtcaccctcgtctcggac
gccacggccgccgtgctcggccacgccgacgcctccgagatcgcgccgaccacgacgttc
aaggacctcggcatcgactcgctcaccgcgatcgagctgcgcaaccggctcgcggaggcg
accgggctgcggctgagtgccacgctggtgttcgaccacccgacacctcgggtcctcgcc
gccaagctccgcaccgatctgttcggcacggccgtgcccacgcccgcgcggacggcacgg
acccaccacgacgagccactcgcgatcgtcggcatggcgtgccgactgcccggcggggtc
gcctcgccggaggacctgtggcagctcgtggcgtccggcaccgacgcgatcaccgagttc
cccaccgaccgcggctgggacatcgaccggctgttcgacccggacccggatgcccccggc
aagacctacgtccggcacggcggcttcctggccgaggccgccggcttcgatgccgcgttc
ttcggcatcagcccgcgcgaggcacgggccatggacccgcagcagcgcgtcatcctcgaa
acctcctgggaggcgttcgagaacgcgggcatcgtgccggacacgctgcgcggcagcgac
accggcgtgttcatgggcgcgttctcccatgggtacggcgccggcgtcgacctgggcggg
ttcggcgccacggccacccagaacagcgtgctctccggccggttgtcgtacttcttcggc
atggagggtccggccgtcacggtcgacacggcgtgctcgtcgtcgctggtcgccctgcac
caggcggcacaggcgctgcggaccggagaatgctcgctggcgctcgccggcggtgtcacg
gtgatgcccaccccgctgggctacgtcgagttctgccgccagcggggactcgcccccgac
ggccgtgccaaggccttcgcggaaggcgccgacggcacgagcttctcggagggcgccggc
gttctggtgctggagcggctctccgacgccgagcgcaacggacacaccgtcctcgcggtc
gtccgctcctccgccgtcaaccaggacggcgcctccaacggcatctccgcacccaacggc
ccctcccagcagcgcgtcatccgccaggccctcgacaaggcggggctcgcccccgccgac
gtggacgtggtggaggcccacggcaccggaaccccgctgggcgacccgatcgaggcacag
gccatcatcgcgacctacggccaggaccgcgacacaccgctctacctcggttcggtcaag
tcgaacatcggacacacccagaccaccgccggtgtcgccggcgtcatcaagatggtcatg
gcgatgcgccacgggatcgcgccgaagacgctgcacgtggacgagccgtcctcgcatgtg
gactggaccgagggcgcggtggaactgctcaccgacgcgaggccgtggcccgacgcggga
cgcccgcgccgcgcgggcgtgtcgtcgctcggtatcagcggtacgaacgcccacgtcatc
cttgagggtgttcccgggccgtctgtcgtggagtcggttgttgacgggttggtgccgttg
ccggtgtcggctcggagtgaggtgagtctgcgggggcaggtggagcggctggaggggtat
ctgcgcgggggtggtgtggatgtggccgcggtcgcacaggggctggtgcgtgagcgtgct
gtcttcggtcaccgtacggtgctgctgggcgatgcccgggtgacgggcgtggcggtggac
cagccgcgcaccgtgttcgtcttccccggccagggcgcccagtgggtcggcatgggcgtg
gaactcatggcccgctccgcggtgttcgccgcgcgtatggaggagtgcgctcaggcgttg
ctgccccacacgggctgggatgtgcgggagatgctgtcacggccggatgtggcggagcgg
gtggaggtggtccagccggccagctgggcggtcgcggtgagcctggccgcgctgtggcag
gcccacggggtcgtgccggacgcggtgatcggacactcccagggcgagatcgcggcggcg
tgcgtggccggagccctcagccttgaggacgccgcccgtgtggtggcgttgcgcagtcag
gtgatcgcggcgcggctggccggccggggagcgatggcttcggtggcgctgccggccggt
gaagtgggtctggtcgagggtgtgtggatcgcggcgcgtaatggtccgtcttcgacggtg
gtggcgggtgagccgtcggcggtggaggaggtggtggcgcggtatgaggccgatggggtg
cgggtgcgtcgtatcgcggtcgactacgcctcccacacgcctcatgtggaggctatcgag
gacgagttggccgaggtgctggaggggatttccggcgggactgggtcggtggcgtggtgg
tccacggtggacagcgcctgggtgacggagccagtggatgaggggtactggtaccggaat
ctgcgtcgtccggtggcgctggatgcggcggtggcggagttggacgggtcggtgttcgtg
gagtgcagtgcccatccggtgctgctgccggcgatggaacaggcccacacggtcgcgtcg
ttgcgcaccggtgacggcggctgggagcggtggctgacagcgttggcgcaggcgtggacc
ctgggcgcggcggtggactgggacacggtggtcgaaccggtgccgggacggctgctggat
ctgccgacctacgcgttcgagcacaggcggtactggctggaggcggccggtgccacggat
ctgtccgcggcggggctgacgggggcggcgcatccgatgctggccgctgtcacagcgctg
cccgccgacgatggtggtgttgttctcaccggccggatctcgttgcgtacgcatccctgg
ctggctgatcatgcggtgcggggcacggttctgctgccgggtacggcgtttgtggagctg
gtcatccgggccggtgacgagaccggttgcggggtggtggatgagctggtcatcgagacc
ccgctcgtggtgccggtgaccgaagccgtggatgtgtcggtgacggtggaaggggccgat
gaggccggacggcggccggtgaccgtccacgcgcgcaccgaaggcaccggcagctggacc
cggcacgccagcggcaccctgacccccgacacccccaacgcttccggtgttgtcggtgcg
gagccgttctcgcagtggccaccggccacggccgcggccgtcgacacctcggagttctac
tcgcgcctggacgcgctgggctaccggttcggacccatgttccgcggaatgcgggctgcc
tggcgtgatggtgacaccgtgtatgccgaggtcgcgctccccgaggaccgtgccgccgac
gcggacggtttcggcatgcacccggcgctgctcgacgcggccttgcagagcggcagcctg
ctcatgctggaatcggacggcgagcagagcgtgcaactgccgttctcctggcacggcgtc
cggttccacgcgacgggcgcgaccatgctgcgggtggcggtcgtaccgggcccggacggc
ctccggctgcatgccgcggacagcgggaaccgtcccgtcgcgacgatcgacgcgctcgtg
acccggtccccggaagcggacctcgcgcccgccgatccgatgctgcgggtcgggtgggcc
ccggtgcccgtacctgccggggccggtccgtccgacgcggacgtgctgacgctgcgcggc
gacgacgccgacccgctcggggagacccgggacctgacgacccgtgttctcgacgcgctg
ctccgggccgaccggccggtgatcttccaggtgaccggtggcctcgccgccaaggcggcc
gcaggactggtccgcaccgctcagaacgagcagcccggccgcttcttcctcgtcgaaacg
gacccgtcagaggtcctggacggcgcgaagcgcgacgcgatcgcggcactcggcgagccc
catgtgcggctgcgcgacggcctcttcgaggcagcccggctgatgcgggccacaccgtcc
ctgacgctcccggacaccgggtcgtggcagctgcggccgtccgccaccggttccctcgac
gacctcgccgtcgtccgcaccgacgccccggaccggccgctcgcggccggcgaggtgcgg
atcgcggtacgcgcggcgggcctgaacttccgggatgtcacggtcgcgctcggcgtggtc
gccgatgagcgtccgctcggcagcgaggccgcgggtgtcgtcctggagaccggccccggt
gtgcacgacctggcgcccggcgaccgggtcctggggatgctcgcgggcgccttcggacca
gtcgcgatcaccgaccggcggctgctcggccggatgccggacggctggacgttcccgcag
gcggcgtccgtgatgaccgcgttcgcgaccgcgtggtacggcctggtcgacctggccggg
ctgcgccccggagagaaggtcctgatccacgcggcggcgaccggcgtcggcgcggcggcc
gtccagatcgcgcggcatctgggcgcggaggtgtacgccaccaccagcgccgcgaagcgc
catctggtggacctggacggagcgcatctggccgattcccgcagcaccgcgttcgccgac
gcgttcccgccggtcgatgtcgtgctcaactcgctcaccggtgaactcctcgacgcgtcc
gtcggcctgctcgcgccgggcggccggttcatcgagatgggcaagaccgacatccgccac
gccgtccagcagccgttcgacctgatggacgccggccccgaccggatgcagcggatcatc
gtcgagctgctcggcctgttcgcgcgcgacgtgctgcacccgctgccggtccacgcctgg
gacgtgcggcaggcacgggaggcgttcggctggatgagcagcgggcgtcacaccggcaag
ctggtgctgacgatcccgcggccgctggaccccgagggggccgtcgtcatcaccggcggc
tccggcaccctcgccggcatcctcgcccgccacctgaaccacccccacacctacctgctc
tcccgcaccccaccccccgacaccacccccggcacccacctcccctgcgacgtcggcgac
ccccaccaactcgccaccaccctcgcccgcatcccccaacccctcaccgccgtcttccac
accgccggaaccctcgacgacgccctgctcgacaacctcacccccgaccgcatcgacacc
gtcctcaaacccaaggccgacgccgcctggcacctgcaccggctcacccgcgacaccgac
ctcgccgcgttcgtcgtctactccgcggtcgccggcctcatgggcagcccggggcagggc
aactacgtcgcggcgaacgcgttcctcgacgcgctcgccgaacaccgccgtacgcaagga
ctgcccgcgcagtccctcgcgtggggcatgtgggcggacgtcagcgcgctcaccgcgaaa
ctcaccgacgcggaccgccagcgcatccggcgcagcggattcccgccgttgagcgccgcg
gacggcatgcggctgttcgacgcggcgacgcgtaccccggaaccggtcgtcgtcgcgacg
accgtcgacctcacccagctcgacggccccgtcgcaccgttgctccgcggtctggccgcg
caccgggccgggccggcgcgcacggtcgcccgcaacgccggcgaagagcccctggccgtg
cgtctcgccgggcgtaccgccgccgagcagcggcgcatcatgcaggaggtcgtgctccgc
cacgcggccgcggtcctcgcgtacgggctgggcgaccgcgtggcggcggaccggccgttc
cgcgagctcggtttcgactcgctgaccgcggtcgacctgcgcaatcggctcgcggccgag
acggggctgcggctgccgacgacgctggtgttcagccacccgacggcggaggcgctcacc
gcccacctgctcgaactgatcgacgctcccaccgcccggatcgccggggagtccctgccc
gcggtgacggccgctcccgtggcggccgcgcgggaccaggacgagccgatcgccatcgtg
gcgatggcgtgccggctgcccggtggtgtgacgtcgcccgaggacctgtggcggctcgtc
gagtccggcaccgacgcgatcaccacgcctcctgacgaccgcggctgggacgtcgacgcg
ctgtacgacgcggacccggacgcggccggcaaggcgtacaacctgcggggcggttacctg
gacggggcggcggagttcgacgcggcgttcttcgacatcagcccgcgcgaagcgctcggc
atggacccgcagcaacgcctgctgctcgaaacggcgtgggaggcgatcgagcgcggccgg
atcagtccggcgtcgctccgcggccgggaggtcggcgtctacgtcggtgcggccgcgcag
ggctacgggctgggcgccgaggacaccgagggcaacgcgatcaccggtggttccacgagc
ctgctgtccggacggctggcgtacgtgctcgggctggagggcccggcggtcaccgtggac
acggcgtgctcgtcgtctctggtcgcgctgcacctggcgtgccaggggctgcgcctgggc
gagtgcgaactcgctctggccggaggggtctccgtactgagttcgccggccgcgttcgtg
gagttctcccgccagcgcgggctcgcggccgacgggcgctgcaagtcgttcggcgcgggc
gcggacggcacgacgtggtccgagggcgtgggcgtgctcgtactggaacggctctccgac
gccgagcggctcgggcacaccgtgctcgccgtcgtccgcggcagcgccgtcacgtccgac
ggcgcctccaacggcctcaccgcgccgaacggactctcgcagcagcgggtcatccggaag
gcgctcgccgcggccgggctgaccggcgccgacgtggacgtcgtcgaggggcacggcacc
ggcacccggctcggcgacccggtcgaggcggacgcgctgctcgcgacgtacgggcagaac
cgtccggcaccggtctggctgggctcgctgaagtcgaacatcggacatgccacggccgcg
gccggtgtcgcgggcgtcatcaagatggtgcaggcgatcggcgcgggcacgatgccgcgg
acactgcatgtggaggagccctcgcccgccgtcgactggagcaccggacaggtgtccctg
ctcggctccaaccggccctggccggacgacgcgcgtccgcgccgggcggccgtctccgcg
ttcgggctcagcgggacgaacgcgcacgtcatcctggaacagcaccgtccggcgcccgtg
gcgtcccagccgccccggccgccccgcgaggagtcccagccgctgccgtgggtgctctcc
gcgcggactccggacgcgctgcgggcccaggcggcccggctgcgcgaccacctcgcggtg
gcaccggacgcggatccgttggacatcgggtacgcgctggccaccagccgcgcccagttc
gcccaccgtgccgcggtcgtcgccaccaccccggacggattccgtgccgcgctcgacggc
ctcgcggacggcgcggaggcgcccggagtcgtcaccgggaccgctcaggagcggcgcgtc
gccttcctcttcgacggccagggcgcccagcgcgccggaatggggcgcgatctccaccgg
cggttccccgtcttcgccgccgcgtgggacgaggtctccgacgcgttcggcaagcacctc
aagcactcccccacggacgtctaccacggcgaacacggcgctctcgcccatgacaccctg
tacgcccaggccggcctgttcacgctcgaagtggcgctgctgcggctgctggagcactgg
ggggtgcggccggacgtgctcgtcgggcactccgtcggcgaggtgaccgcggcgtacgcg
gcgggggtgctcaccctggcggacgcgacggagttgatcgtggcccgggggcgggcgctg
cgggcgctgccgcccggggcgatgatcgcggtcgacggaagcccggcggaggtcggcgcc
cgcacggatctggacatcgccgcggtcaacggcccgtccgccgtggtgctcgccggttcg
ccggacgacgtggcggcgttcgaacgggagtggtcggcggccgggcggcgcacgaaacgg
ctcgacgtcgggcacgcgttccactcccggcacgtcgacggtgcgctcgacggcttccgt
acggtgctggagtcgctcgcgttcggcgcggcgcggctgccggtggtgtccacgacgacg
ggccgggacgccgcggacgacctcataacgcccgcgcactggctgcgccatgcgcgtcgg
acggtgctgttctcggatgccgtccgggagctggccgaccgcggcgtcaccacgttcgtg
gccgtcggcccgtccggctccctggcgtcggccgcggcggagagcgccggggaggacgcc
gggacctaccacgcggtgctgcgcgcccggaccagcgaggagaccgcggcgctgaccgcc
ctcgccgagctgcacgcccacggcgtcccggtcgacctggccgcggtactggccggtggc
cggccagtggacctccccgtgtacgcgttccagcaccgctcctactggctggccccggcc
gtggcgggggcgccggccaccgtggcggacaccgggggcccggcggagtccgagccggag
gacctcaccgtcgccgagatcgtccgtcggcgcaccgcggcgctgctcggcgtcacggac
cccgccgacgtcgatgcggaagcgacgttcttcgcgctcggtttcgactcactggcggtg
cagcggctgcgcaaccagctcgcctcggcaaccgggctggacctgccggcggccgtcctg
ttcgaccacgacaccccggccgcgctcaccgcgttcctccaggaccggatcgaggccggc
caggaccggatcgaggccggcgaggacgacgacgcgcccaccgtgctctcgctcctggag
gagatggagtcgctcgacgccgcggacatcgcggcgacgccggccccggagcgcgcggcc
atcgccgatctgctcgacaagctcgcccatacctggaaggactaccgatga
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