Streptomyces lividans: SLIV_10860
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Entry
SLIV_10860 CDS
T03222
Name
(GenBank) putative AIPM/Hcit synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
slv
Streptomyces lividans
Pathway
slv00290
Valine, leucine and isoleucine biosynthesis
slv00620
Pyruvate metabolism
slv01100
Metabolic pathways
slv01110
Biosynthesis of secondary metabolites
slv01210
2-Oxocarboxylic acid metabolism
slv01230
Biosynthesis of amino acids
Module
slv_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
slv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SLIV_10860
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SLIV_10860
Enzymes [BR:
slv01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SLIV_10860
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
Asp_protease
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
AIJ13167
UniProt:
D6ERP4
LinkDB
All DBs
Position
complement(2495415..2497019)
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AA seq
534 aa
AA seq
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MTATSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGANPRD
TEFFARARQEIDFKHAQLVAFGSTRRAGANAAEDHQVKALLDSGAQVITLVAKSHDRHVE
LALRTTLDENLAMVADTVSHLKTQGRRVFVDCEHFFDGYRANPEYAKSVVRTASEAGADV
VVLCDTNGGMLPAQIQAVVATVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTA
NGYGERVGNANLFPVVAALELKYGKQVLPEGRLREMTRISHAIAEVVNLTPSTHQPYVGV
SAFAHKAGLHASAIKVDPDLYQHIDPELVGNTMRMLVSDMAGRASIELKGKELGIDLGGD
RELVGRVVERVKERELAGYTYEAADASFELLLRAEVERRPLKYFEVESWRAITEDRPDGS
HANEATVKLWAKGERIVATAEGNGPVNALDRSLRVALEKIYPELAKLDLVDYKVRILEGV
HGTQSTTRVLISTSDGTGEWATVGVAENVIAASWQALEDAYTYGLLRAGVAPAE
NT seq
1605 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcaaccagcgaactcgacgattcgttccacgtcttcgacaccaccctgcgcgac
ggcgcgcagcgcgagggcatcaacctcacggtcgcggacaagctggccatcgcacggcac
ctggacgacttcggggtgggcttcatcgagggcggctggcccggcgccaacccgcgggac
accgagttcttcgcccgcgcccggcaggagatcgacttcaagcacgcccagctggtcgcc
ttcggctccacccgccgcgcgggcgcgaacgccgccgaggaccaccaggtcaaggcgctg
ctcgactccggcgcccaggtgatcaccctggtcgccaagtcgcacgaccggcacgtcgaa
ctggccctgcgcaccacgctggacgagaacctcgcgatggtggccgacacggtctcgcac
ctgaagacgcagggccgccgggtcttcgtcgactgcgagcacttcttcgacggctaccgc
gccaaccccgagtacgcgaagtcggtcgtgcgcaccgcctccgaggccggcgccgacgtc
gtcgtcctgtgcgacaccaacggcggcatgctcccggcgcagatccaggcggtggtcgcc
acggtgctcgccgacaccggcgcccggctcggcatccacgcccaggacgacaccggctgc
gccgtcgccaacaccctcgccgccgtcgacgcgggcgcgacccacgtccagtgcacggcc
aacggctacggcgagcgggtcggcaacgccaacctgttccccgtcgtggccgcgctggag
ctgaagtacggcaagcaggtgctgcccgagggccggctgcgcgagatgacccgcatctcc
cacgccatcgccgaggtcgtcaacctcacgccctccacccaccagccctacgtgggcgtc
tccgccttcgcccacaaggccggcctgcacgcctccgcgatcaaggtcgacccggacctc
taccagcacatcgaccccgaactggtcggcaacaccatgcggatgctggtctccgacatg
gcgggacgtgcctccatcgagctgaagggcaaggagctcgggatcgacctcggcggcgac
cgcgagctggtcggccgggtcgtggagcgggtcaaggagcgcgagctggccggctacacc
tacgaggccgccgacgcgagcttcgagctgctgctgcgcgccgaggtcgagcgaaggccg
ctgaagtacttcgaggtcgagtcctggcgcgcgatcaccgaggaccgccccgacggcagc
cacgccaacgaggccacggtcaagctctgggccaagggcgagcgcatcgtcgccaccgcc
gagggcaacggcccggtcaacgccctggaccggtcgctgcgcgtggccctggagaagatc
taccccgagctggccaagctcgacctggtcgactacaaggtccgcatcctggagggcgtg
cacggcacccagtccaccaccagggtcctcatctccacgtccgacggcacgggggagtgg
gccacggtgggtgtcgcggagaacgtcatcgccgcctcctggcaggccctggaggacgcg
tacacgtacgggctgctgcgggcgggggtcgcgcccgccgagtga
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