Streptomyces lividans: SLIV_27265
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Entry
SLIV_27265 CDS
T03222
Symbol
murF
Name
(GenBank) putative UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
slv
Streptomyces lividans
Pathway
slv00300
Lysine biosynthesis
slv00550
Peptidoglycan biosynthesis
slv01100
Metabolic pathways
slv01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slv00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SLIV_27265 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SLIV_27265 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SLIV_27265 (murF)
Enzymes [BR:
slv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SLIV_27265 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AIJ16364
UniProt:
D6EJ15
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All DBs
Position
6099156..6100571
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AA seq
471 aa
AA seq
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MITLSLAEIAEVVGGRMHDIPDASAEVTGPVVRDSREAGPGSLFVAFVGERADGHDFAAR
VVEAGAVAVLGSRPVGVPAIVVDDVQAALGALARHVVRRLGTTLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSMNNEVGLPLTALTATDETKFLVLEMGARGIGHIRYLTELTPPKI
GAVLNVGSAHIGEFGGREQIAQAKGELVEALPPAEEGGAAILNADDPLVRAMASRTKAKV
ILFGESGEADVRAENVRLTDTGQPSFSLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESTKAALRALVAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREARWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVATALLETGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctctcactcgccgagatcgcagaagtcgtcggcgggcggatgcacgacata
ccggacgcgtccgccgaggtcaccgggccggtcgtccgggactcccgggaagccgggccc
ggcagcctcttcgtcgccttcgtgggcgaacgggccgacggccacgacttcgccgcgcgg
gtcgtcgaagcgggtgcggtggccgtcctcggctcccgtcccgtcggcgtgccggcgatc
gtcgtggacgacgtccaggccgccctgggcgccctcgcccggcacgtcgtgcgacgcctc
ggcaccaccctcgtggccctcaccgggtcggccggcaagaccagcaccaaggacctgatc
gcccaggtactgcgccgcaaggcgcccacggtcttcacgcccggttccatgaacaacgag
gtggggctgccgctcaccgcgctcaccgccaccgacgagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccggtacctcaccgaactcaccccgccgaagatc
ggcgcggtcctcaacgtcggctccgcgcacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgaactcgtcgaggccctgccgccggccgaggagggcggcgccgcg
atcctcaacgcggacgacccgctcgtacgggccatggcctcccgaacgaaggcgaaggtg
atccttttcggagagtccggcgaagcggacgttcgcgccgagaacgtgcgactcacggac
accggacagccttccttcagccttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagacgagatcgccaccgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccaccaaggccgcgctgcgtgcgctggtcgccatgggcaaggggcgtcgt
acgtgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagg
gaagcccgatggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccaggagac
gtcgtgctcgtgaaggcgtcccgttcggtgggtctggagagcgtcgccacggcgctcctc
gagaccggcgccgagggtgaggttgccgcccgatga
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