Streptomyces lavendulae subsp. lavendulae: SLAV_26795
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Entry
SLAV_26795 CDS
T05314
Symbol
murF2
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
slx
Streptomyces lavendulae subsp. lavendulae
Pathway
slx00300
Lysine biosynthesis
slx00550
Peptidoglycan biosynthesis
slx01100
Metabolic pathways
slx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SLAV_26795 (murF2)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SLAV_26795 (murF2)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SLAV_26795 (murF2)
Enzymes [BR:
slx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SLAV_26795 (murF2)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
PhageMin_Tail
Motif
Other DBs
NCBI-ProteinID:
ATZ27151
UniProt:
A0A2K8PK87
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Position
6008120..6009544
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AA seq
474 aa
AA seq
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MIALSLAEIADITGGRPHDIPDPSVRIGGPVVIDSRQVEPGSLFAAFEGEHVDGHDYAER
AVAAGAAAVLAARPVGVPAIVVPDVEKALGALARTVVERLGTDVVALTGSAGKTSTKDLI
AQVLQHHAPTVWTPGSLNNEIGLPLTALKATAETRHLVLEMGARGIGHIAYLTGLTPPRI
GLVLNVGTAHIGEFGGREAIAQAKGELVEALPAEADGGVAVLNADDLLVRAMSARTKART
VLFGEAEDADVRATEVRMTPAGQPSFTLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHVL
GMSVEEIATALSAAGTLSRWRMEVTERADGVTIVNDAYNANPESMRAALRALAAMGDSAR
ARGGRTWAVLGPMAELGDAALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVLVSDAQAAVDLLRSELRPGDVVLVKASRSIGLERVAQALLDSEGEVAGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctttccctcgccgagatcgccgacatcaccggcgggcggccccacgacata
ccggatccctcggtgcggatcggcggccccgtcgtcatcgactcccgccaggtggagccc
gggagcctgttcgccgccttcgagggcgagcacgtcgacggccacgactacgccgagcgc
gcggtcgcggccggcgccgcggccgtcctcgccgcccgcccggtcggcgttccggcgatc
gtggtccccgacgtggagaaggccctcggcgccctcgcccgcaccgtcgtcgaacgcctc
ggcaccgacgtggtggcgctgaccggttcggccggcaagacgtccaccaaggacctcatc
gcgcaggtgctccagcaccacgcgcccacggtgtggacgcccggatccctcaacaacgag
atcggccttccgctcacggccctgaaggccaccgccgaaacccggcacctggtcctggag
atgggcgcccgcggcatcggccacatcgcctacctgaccggtctgaccccgccgcggatc
ggcctcgtcctgaacgtcgggaccgcccacatcggcgagttcggcggtcgcgaggccatc
gcccaggccaagggagagctggtcgaggccctgccggcggaagccgacggcggggtggcc
gtcctcaacgccgacgacctgctggtgcgggccatgtccgcccgcaccaaggcccgtacc
gtcctgttcggggaggccgaggacgccgacgtacgggccaccgaggtgcggatgacaccc
gccggacagccctccttcacactccacaccccgaccgggtgcagcgatgtgaccttgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgtcctg
ggcatgtccgtcgaagagatcgccacggcgctctccgcggcgggcacgctgtctcggtgg
cggatggaggtcaccgagcgcgcggacggcgtgacgatcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgggccgccctgcgcgcacttgccgcgatgggcgactccgccagg
gcgagggggggacgtacgtgggcggtgctcggccccatggccgagctcggcgacgctgcg
ctggccgaacacgacgcggtgggacggctcgccgtccggctcaacgtgagcaagctcgtg
gcagtcgggggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgctcgtgtccgacgcgcaggcggcggtggacctgttgcgcagtgaa
ctgcgcccgggggacgtcgtgctggtgaaggcttccaggtcgatcggcctggaacgggtc
gcgcaggcgctgctcgacagcgagggcgaggtcgccggccgatga
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