Streptomyces avermitilis: SAVERM_2228
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Entry
SAVERM_2228 CDS
T00126
Symbol
hemE
Name
(GenBank) putative uroporphyrinogen decarboxylase
KO
K01599
uroporphyrinogen decarboxylase [EC:
4.1.1.37
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00860
Porphyrin metabolism
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
sma01240
Biosynthesis of cofactors
Module
sma_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SAVERM_2228 (hemE)
Enzymes [BR:
sma01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.37 uroporphyrinogen decarboxylase
SAVERM_2228 (hemE)
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Gene cluster
GFIT
Motif
Pfam:
URO-D
Methyltransf_11
Motif
Other DBs
NCBI-ProteinID:
BAC69939
UniProt:
Q82KY4
LinkDB
All DBs
Position
complement(2707230..2708297)
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AA seq
355 aa
AA seq
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MSANDRPATGQPTATYESAFLKACRREPVPHTPVWFMRQAGRSLPEYLKVREGIPMLESC
MRPELVAEITLQPVRRHNVDAAIYFSDIVVPLKAIGIDLDIKPGVGPVVEKPIRTRADLA
QLRDLTPEDVSYVTEAIKLLTAELGETPLIGFAGAPFTLASYLVEGGPSKNHEHTKALMY
GDPQLWADLLDRLAEITSAFLKVQIEAGASAVQLFDSWVGALAPADYRRSVMPASTKVFQ
AVESYGVPRIHFGVGTGELLGLMGEAGADVVGVDWRVPLDEAARRVGTGKALQGNLDPAV
LFSTTEAVETKTREVLDAAAGLEGHVFNLGHGVPPTTDPDALTRLVEYVHTQTAR
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgccaacgaccgccccgcgacgggccagccgacagccacgtacgagtccgccttc
ctcaaggcgtgcaggcgcgagcccgtgccgcacacgccggtgtggttcatgcggcaggcc
gggcgctcgctgccggagtacctcaaggtgcgcgagggcatccccatgctcgagtcgtgc
atgcgccccgagctggtcgccgagatcacactccagccggtccgccggcacaacgtggac
gcggcgatctacttcagcgacatcgtcgtaccgctcaaggccatcggcatcgacctcgac
atcaagccgggcgtcggcccggtcgtcgagaagccgatccgcacccgcgccgacctggcc
cagctgcgcgacctgacccccgaggacgtctcgtacgtcaccgaggcgatcaagctgctg
acggccgagctcggcgagaccccgctcatcggtttcgcgggcgcgcccttcaccctcgcg
agctatctcgtggagggcggcccgtccaagaaccacgagcacaccaaggcgctcatgtac
ggcgacccgcagctgtgggccgacctcctcgaccgtctcgccgagatcacctcggccttc
ctcaaggtccagatcgaggcgggcgcctccgccgtccagctcttcgactcctgggtcggc
gcgctcgcccccgccgactaccgccgctcggtgatgcccgcctccaccaaggtcttccag
gccgtcgagtcgtacggcgtgccccgtatccacttcggtgtcggcaccggtgagctgctc
ggcctcatgggcgaggcgggcgcggacgtcgtcggcgtcgactggcgcgtcccgctcgac
gaggccgcccgccgcgtcggcaccgggaaggcgctccagggcaacctcgacccggcggtc
ctgttctccacgacggaggcggtggagaccaagacccgcgaggtgcttgatgcggccgcc
ggtctcgagggccatgtcttcaacctcggccacggcgtcccgccgaccaccgacccggac
gcgctgacccgcctcgtggagtacgtccacacgcagaccgcccgctga
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