Streptomyces avermitilis: SAVERM_4376
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Entry
SAVERM_4376 CDS
T00126
Symbol
bkdF
Name
(GenBank) putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00280
Valine, leucine and isoleucine degradation
sma00640
Propanoate metabolism
sma00785
Lipoic acid metabolism
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
sma01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SAVERM_4376 (bkdF)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SAVERM_4376 (bkdF)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAVERM_4376 (bkdF)
Enzymes [BR:
sma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
SAVERM_4376 (bkdF)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
BAC72088
UniProt:
Q79Z50
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All DBs
Position
5356305..5357525
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AA seq
406 aa
AA seq
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MTVESTAARKPRRSAGTKSAAAKRTSPGAKKSPSTTGAEHELIQLLTPDGRRVKNPEYDA
YVADITPEELRGLYRDMVLSRRFDAEATSLQRQGELGLWASMLGQEAAQIGSGRATRDDD
YVFPTYREHGVAWCRGVDPTNLLGMFRGVNNGGWDPNSNNFHLYTIVIGSQTLHATGYAM
GIAKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRV
PLYQRAQGYGFPGVRVDGNDVLACLAVTKWALERARRGEGPTLVEAFTYRMGAHTTSDDP
TKYRADEEREAWEAKDPILRLRTYLEASNHADEGFFAELEVESEALGRRVREVVRAMPDP
DHFAIFENVYADGHALVDEERAQFAAYQASFTTEPDGGSAAGQGGN
NT seq
1221 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgaaagccgcgacgcagcgccggtacgaagagcgcc
gcagccaagcgcaccagccccggcgccaagaagtcaccgagcacgaccggcgccgagcac
gagctgattcagctgctcacgcccgacggccggcgggtgaagaaccccgagtacgacgcg
tacgtcgcggacatcacccccgaagagctgcgcggtctgtaccgggacatggtgctgagc
cgccgcttcgacgcagaggccacctccctgcaacgccagggcgagctgggcctgtgggcc
tcgatgctcgggcaggaggccgcccagatcggctcgggccgggccacccgtgacgacgac
tacgtcttcccgacctaccgcgagcacggcgtcgcctggtgccgcggggtcgaccccacc
aacctgctcggcatgttccgcggcgtgaacaacggcggctgggatcccaacagcaacaac
ttccacctctacacgatcgtcatcggctcgcagacgctgcacgccaccggctacgccatg
ggtatcgccaaggacggcgccgactcggccgtgatcgcgtacttcggtgacggcgcctcc
agccagggtgacgtcgccgaatcgttcaccttctccgcggtctacaacgcccctgtcgtc
ttcttctgccagaacaaccagtgggcgatctccgagcccaccgagaagcagacccgcgtc
ccgctctaccagcgcgcgcagggctacggcttcccgggcgtccgcgtcgacggcaacgac
gtactggcctgcctcgccgtcaccaagtgggccctcgagcgggcccgccggggcgagggg
cccacgttggtcgaggcgttcacgtaccgcatgggcgcgcacaccacctccgacgacccg
accaagtaccgggccgacgaggagcgcgaggcgtgggaggcgaaggacccgatcctgcgt
ctgcgcacgtatctcgaggcctcaaaccacgcggacgagggattcttcgcggaactcgag
gtggagagcgaggcgttgggaaggcgagtgcgcgaagtggtgcgtgccatgccggacccg
gaccacttcgccatcttcgagaacgtgtacgcggacgggcatgcgctcgtcgacgaggag
cgggcgcagttcgccgcctaccaggcgtcgttcacgacggagcctgacggcggctccgcc
gcgggacaggggggtaactga
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