Streptomyces avermitilis: SAVERM_4716
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Entry
SAVERM_4716 CDS
T00126
Symbol
ilvD1
Name
(GenBank) putative dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00290
Valine, leucine and isoleucine biosynthesis
sma00770
Pantothenate and CoA biosynthesis
sma01100
Metabolic pathways
sma01110
Biosynthesis of secondary metabolites
sma01210
2-Oxocarboxylic acid metabolism
sma01230
Biosynthesis of amino acids
Module
sma_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sma_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAVERM_4716 (ilvD1)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SAVERM_4716 (ilvD1)
Enzymes [BR:
sma01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SAVERM_4716 (ilvD1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
BAC72428
UniProt:
Q82E99
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Position
5746979..5748832
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLQPVGRI
VSEAITAAGGIAREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICI
SNCDKITPGMLMAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKGLYEDAART
VVDITRRYYEQDDESVLPRNIATHAAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGL
DEINEVSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHSVHSP
SLSDWLKTWDVRAGSPSPEAIELWHAAPGCVRSSEAFSQSERWEALDEDAEGGCIRSAEH
AYSKDGGLAVLKGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQDEAVDKILRKEITHGD
VVVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKTCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVQDGDRIRIDIPNRTIDLLVDEAELSRRDQALNGVYAPVNRERKVSAALRAYAA
MATSADKGAVRDVSKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggtcgcaacatggcgggcgcccgcgcc
cttatgcgcgcctccggtgtaccgggcgcggacatcggccggaagccgatcatcgcggtc
gccaactccttcacggagttcgtgcccggccacacccacctccagccggtcggccggatc
gtcagcgaggccatcacggccgccggcggcatcgcgcgcgagttcaacacgatcgcggtc
gacgacggcatcgcgatgggccacggcggcatgctgtactccctcccgtcccgcgacctg
atcgcggactcggtcgagtacatggtcgaggcccactgcgccgacgccctgatctgcatc
tcgaactgcgacaagatcacgcccggcatgctcatggccgctctgcgcctgaacatcccg
acggtcttcgtctccggcggccccatggagtccggccgcgccaccctggtcgacggcacg
gtccgtacgctcgacctggtcgacgcgatctccgacgccgtgaacgacaagatctcggac
gaggacatcctccgtatcgaggagaacgcctgtcccacctgcggctcctgctccggcatg
ttcaccgccaactcgatgaactgcctgaccgaggccatcggcctgagcctgcccggcaac
ggctcggtcctcgccacgcacacggcccgcaagggtctgtacgaggacgcggcccgcacg
gtcgtggacatcacgcgccgttactacgagcaggacgacgagtcggtcctgccccgcaac
atcgccacgcacgccgccttcgagaacgccatggccctcgacatcgccatgggcggctcc
accaacacgatcctgcacctgctggccgccgcccaggaagcgggcgtccccttcggcctg
gacgagatcaacgaggtctcgcgccgcgtgccctgcctcgccaaggtcgccccgaacgtc
gccaaggaccgtacgtactacatggaggacgtgcaccgcgcgggcggcatcccggccctg
ctgggcgagctgcaccgggccggcctgctgaacgaggacgtgcactcggtgcacagcccg
tccctctccgactggctgaagacgtgggacgtgcgggcgggttccccgtcccccgaggcc
atcgaactgtggcacgcggcccccggctgcgtccgctcctccgaggccttctcccagtcc
gagcgctgggaggcgctcgacgaggacgcggagggcggctgcatccgctccgccgaacac
gcgtactccaaggacggcggcctcgcggtcctcaagggcaacctggcggtcgacggctgc
gtcgtgaagacggcgggcgtcgacgagtcgatctggaccttcgagggcccggcggtcgtc
tgcgagtcgcaggacgaggccgtcgacaagatcctccgcaaggagatcacccacggcgac
gtggtcgtcatccgctacgagggccccaagggcggccccggcatgcaggagatgctctac
ccgacgtcgttcctgaagggccggggcctcggcaagacctgtgccctgatcacggacggc
cgtttctccggcggcacctcgggcctgtcgatcggccacgcctcccccgaggcggcgtcc
ggcggcacgatcgcgctggtccaggacggcgaccgcatccgcatcgacatcccgaaccgc
acgatcgacctcctggtggacgaggccgaactgtcccgccgcgaccaggccctgaacggc
gtctacgcccccgtgaaccgcgagcgcaaggtctccgcggccctgcgcgcgtacgccgcg
atggccacgagcgcggacaagggcgcggtccgggacgtgtcgaagctgggctga
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