Streptomyces avermitilis: SAVERM_5342
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Entry
SAVERM_5342 CDS
T00126
Symbol
iolA
Name
(GenBank) putative methylmalonic acid semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00280
Valine, leucine and isoleucine degradation
sma00410
beta-Alanine metabolism
sma00562
Inositol phosphate metabolism
sma00640
Propanoate metabolism
sma01100
Metabolic pathways
sma01120
Microbial metabolism in diverse environments
sma01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SAVERM_5342 (iolA)
00562 Inositol phosphate metabolism
SAVERM_5342 (iolA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SAVERM_5342 (iolA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
SAVERM_5342 (iolA)
Enzymes [BR:
sma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
SAVERM_5342 (iolA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
SAVERM_5342 (iolA)
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Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
BAC73054
UniProt:
Q82CK3
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Position
6474502..6476004
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AA seq
500 aa
AA seq
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MTKIVNHWIGGKTVEGASGTYGPVTDPATGAVTTKVAFATVDEVDAAVAAAKDAYATWGQ
SSLAKRSTILFKFRALLDANRDAIAELITAEHGKVHSDALGEVARGLEIVDLACGITVQL
KGELSTEVASRVDVSSIRQPLGVVAGITPFNFPAMVPMWMFPLAIACGNTFVLKPSEKDP
SAALKLAELLAEAGLPDGVFNVVHGDKVAVDRLLEHPDVKAVSFVGSTPIARYIHTTASA
KGKRVQALGGAKNHMLVLPDADLDAAADAAVSAAYGSAGERCMAISAVVAVGAIGDELVE
KIRERAEKIKIGPGNDPASEMGPLITKAHRDKVASYVAGAAAQGSEVVLDGTGHTVDGFE
DGHWIGLSLLDKVPTSADAYRDEIFGPVLCVLRVDSYEEGLALINDSPFGNGTAIFTRDG
GAARRFQLEVEAGMVGVNVPIPVPVGYHSFGGWKDSLFGDHHIYGNDGTHFYTRGKVVTT
RWPDPSEAPAGVDLGFPRNH
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atgacgaagatcgtcaaccactggatcggcggcaagaccgtcgaaggcgcgtcgggcacg
tacgggccggtcaccgacccggcgaccggcgcggtcaccacgaaggtcgccttcgcgacg
gtcgacgaggtggacgccgcggtcgccgccgcgaaggacgcctacgcgacctggggccag
tcctcgctggccaagcggagcacgatcctcttcaagttccgggcgctgctcgacgccaac
cgggacgcgatcgccgagctgatcaccgcagagcacggcaaggtgcactccgacgcgctc
ggcgaggtcgcgcgcgggctggagatcgtcgacctggcgtgcggcatcaccgtgcagctg
aagggcgagctgtcgaccgaggtcgccagccgggtggacgtctcgtcgatccggcagccg
ctgggtgtcgtcgcgggcatcacgccgttcaacttcccggccatggtgccgatgtggatg
ttcccgctcgccatcgcgtgcggcaacacgttcgtgctgaagccgtccgagaaggacccg
tcggcggccctgaagctggccgagctgctggccgaggccggtctgccggacggcgtcttc
aacgtcgtacacggggacaaggtcgcggtcgaccgcctcctggagcacccggacgtcaag
gcggtgtccttcgtcggctcgacgccgatcgcccgctacatccacacgaccgcctccgcg
aagggcaagcgtgtccaggcgctcggcggcgccaagaaccacatgctggtcctcccggac
gcggacctggacgcggccgccgacgccgccgtctcggccgcgtacggctcggccggcgag
cgctgcatggcgatctccgcggtcgtcgcggtgggcgccatcggggacgagctggtggag
aagatccgcgagcgcgccgagaagatcaagatcggtccgggcaacgacccggcctccgag
atgggtccgctgatcaccaaggcgcaccgcgacaaggtggcctcgtatgtggcgggcgcg
gcggcgcagggctccgaggtcgtcctcgacggcacgggccacacggtcgacggcttcgag
gacggccactggatcggcctctcgctgctcgataaggtgccgacgtccgcggacgcgtac
cgggacgagatcttcggcccggtgctgtgcgtgctgcgcgtggactcgtacgaggagggc
ctcgccctcatcaacgactcgccgttcggcaacggcaccgcgatcttcacccgggacggc
ggcgccgcccgccgcttccagctggaggtcgaggcgggcatggtcggtgtgaacgtgccg
attccggtgccggtgggctaccactccttcgggggctggaaggactcgctcttcggcgac
caccacatctacggcaacgacggcacgcacttctacacccgcggcaaggtcgtcaccacc
cgctggccggacccgtccgaggccccggcgggcgtcgacctgggcttcccgcgcaaccac
tga
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