Streptomyces avermitilis: SAVERM_5452
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Entry
SAVERM_5452 CDS
T00126
Symbol
folC
Name
(GenBank) putative folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sma
Streptomyces avermitilis
Pathway
sma00790
Folate biosynthesis
sma01100
Metabolic pathways
sma01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sma00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SAVERM_5452 (folC)
Enzymes [BR:
sma01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SAVERM_5452 (folC)
6.3.2.17 tetrahydrofolate synthase
SAVERM_5452 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BAC73164
UniProt:
Q82CA2
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Position
6614987..6616348
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AA seq
453 aa
AA seq
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MPARPADPETDKALREVEAELATRWGETKLEPSVSRITALMDVLGDPQRAYPSIHITGTN
GKTSTARMIEALLGAFDLRTGRYTSPHVQSVTERISLDGAPISAERFIETYDDIKPYIEM
VDGQQEFRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLD
HTDRLGETPGEIASEKAGIVKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVV
SRQVAVGGQLLTLRGLGGEYEEVYLPLHGPYQAHNAAVALAAVEAFFGVGSQRPEPLDLD
TVRKAFAAVTAPGRLEVVRRSPTVVLDAAHNPAGARATAEAVGEAFDFSRLIGVVGASGD
KNVRGLLEAFEPIFAEVVITQNSSHRAMDADELAAIAVEVFGEDRVQVEPRLDDALEAAI
TLAEEEGEFAGGGVLVTGSVITVGEARLLLGRG
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
gtgcccgcgcgtcccgccgaccccgagaccgacaaagcgctgcgcgaggtcgaggccgag
ctcgccacccgctggggcgagaccaaactggagccctccgtcagccgtatcaccgccctg
atggacgtgctcggggacccgcagcgcgcgtacccctcgatccacatcacggggacgaac
ggcaagacctccaccgcccgcatgatcgaggccctcctcggcgccttcgacctgcgcacc
ggccggtacaccagcccgcacgtccagtcggtcaccgagcgcatcagcctcgacggcgcc
ccgatctccgccgagcgcttcatcgagacgtacgacgacatcaagccgtacatcgagatg
gtcgacggccagcaggagttccggctctccttcttcgaggtcctgaccggcatggcgtac
gcggccttcgcggacgcgcccgtcgacgtggcggtcgtggaggtggggatgggcggcagc
tgggacgccaccaacgtcatcgacggtgacgtcgccgtcgtcacgcccatcgacctcgac
cacaccgaccggctcggcgagacacccggcgagatcgcctcggagaaggccggcatcgtc
aagcaggacgccaccgtgatcctggcccagcagccggtggacgcggcgcaggtgctgctg
aagaaggccgtggaggtcgacgcgaccgtggcccgggagggcctggagttcggggtcgtc
tcacgtcaggtcgccgtcggcggacagctgctgacgctgcgtggcctcggcggcgagtac
gaggaggtgtacctgccgctgcacggtccgtaccaggcgcacaacgcggccgtcgcgctc
gccgccgtcgaggcgttcttcggcgtcggctcccagcggcccgagccgctcgacctcgac
acggtccgcaaggccttcgccgcggtgaccgcgccgggccgcctggaggtcgtacgccgc
tcgccgaccgtcgtcctggacgcggcccacaatccggcgggcgcccgcgccaccgcagag
gccgtcggcgaggccttcgacttcagccggctcatcggagtggtgggggccagcggcgac
aagaacgtccgggggctgctcgaggccttcgagccgatcttcgccgaggtcgtgatcacc
cagaactccagccatcgcgcgatggacgccgacgagctggccgcgatcgccgtggaggtc
ttcggcgaggaccgcgtccaggtcgagccgcgcctcgacgacgcgctggaggccgcgatc
acactcgccgaggaagagggcgagttcgcgggcggcggcgtcctcgtcaccggctccgtc
atcaccgtcggcgaggcccgactgctcctcgggaggggctga
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