Serratia marcescens subsp. marcescens Db11: SMDB11_0058
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Entry
SMDB11_0058 CDS
T03985
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smac
Serratia marcescens subsp. marcescens Db11
Pathway
smac00290
Valine, leucine and isoleucine biosynthesis
smac00620
Pyruvate metabolism
smac01100
Metabolic pathways
smac01110
Biosynthesis of secondary metabolites
smac01210
2-Oxocarboxylic acid metabolism
smac01230
Biosynthesis of amino acids
Module
smac_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smac00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SMDB11_0058 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMDB11_0058 (leuA)
Enzymes [BR:
smac01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SMDB11_0058 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
CDG10656
UniProt:
A0ABC9ID71
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Position
complement(70868..72442)
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AA seq
524 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKIQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQIKNSRVCGLARCVDKDIDVAAEALRVAEAFRIHVFLATSTLHIESKLKRSFDEVLE
MAVRSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAIHAGATTINIPDTVGYTTPNQF
GGIITTLYDRVPNIDKAIISVHCHDDLGMAVGNSIAAVQAGARQVEGTLNGIGERAGNCS
LEEVIMAIKVRQDIMNVHTNINHQEIFRTSQIVSQLCNMPIPANKAIVGANAFAHSSGIH
QDGVLKNRENYEIMTPQSIGLKDVQLNLTSRSGRAAVKHRMEEMGYQEQDYNLDTLYAAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFSLGYFSVQSGSSIMATASVKLICGGEEKA
EAATGNGPVDAVYQAINRITDYPIELVKYQLTAKGHGRDALGQVDIVVSYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRSQQVEKEKQRLQQNKHQNNQETV
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgagccaacaagtcattattttcgataccacgctgcgtgacggcgaacaggcattgcag
gccagcctgagcgtaaaagagaagattcagattgcgctggcgctggaaagaatgggcgtt
gacgtgatggaagtcggcttcccggtctcttcgccgggcgacttcgaatcggtgcaaacc
atcgcgcgccagatcaagaacagtcgcgtctgcggcctggcccgctgcgtggacaaagac
atcgacgtggccgccgaagcgctgcgcgtcgctgaagcgttccgcatccacgtgttcctg
gccacctccaccctgcatatcgaatcgaagctgaagcgctcgttcgacgaagtgttggag
atggcggtgcgctcggtcaaacgcgcccgcaactacaccgacgacgtagagttctcctgt
gaagacgccggccgcacgccgatcgacaatctgtgccgcgtggtcgaagccgccatccac
gccggcgccaccaccatcaatattccggacaccgtcggctacaccacgccgaaccagttc
ggcggcatcatcaccaccttgtatgaccgcgtgccgaacatcgacaaagccatcatttcc
gtacactgccacgacgatttgggcatggcggtcggcaactccattgccgcggtccaggcc
ggcgcccgtcaggtggaaggcaccctgaacggcatcggtgagcgcgccggcaactgctcg
ctggaagaggtgatcatggcgattaaagtgcgccaggacatcatgaacgtgcacaccaac
atcaatcatcaggaaatcttccgcaccagccagatcgtcagccagctgtgcaacatgccg
atcccggccaacaaggcgatcgtcggcgccaacgccttcgcccactcctccgggattcac
caggacggcgtgctgaagaaccgcgaaaactacgaaatcatgaccccgcagtcgatcggc
ctgaaagacgtgcagttgaacctgacctcccgctccggccgcgcggcggtgaaacaccgc
atggaagagatgggctaccaggagcaggactacaacctggataccctgtatgccgccttc
ctgaagctggccgacaaaaaaggccaggtgttcgactatgacctggaggcgctggccttc
atcaataaacagcaggaagagccggagcacttcagcctgggctacttcagcgtgcagtcc
ggcagcagcatcatggccaccgcctcggtgaaactgatctgcggcggcgaagagaaagcc
gaagccgccaccggcaacggcccggtcgatgcggtctatcaggcgatcaatcgcatcacc
gattacccgatcgagctggtgaagtaccagttgaccgccaagggccatggccgcgacgcg
ctgggccaggtggatatcgtcgtctcttacaacggccgccgcttccacggcgtaggcctg
gcgaccgacatcgtcgaatcctctgccaaggcaatggtgcacgtgttgaacaatatttgg
cgctcacagcaggtagaaaaagaaaagcagcgcctgcagcaaaacaaacatcaaaataat
caggaaacggtgtga
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