Serratia marcescens subsp. marcescens Db11: SMDB11_0071
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Entry
SMDB11_0071 CDS
T03985
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smac
Serratia marcescens subsp. marcescens Db11
Pathway
smac00300
Lysine biosynthesis
smac00550
Peptidoglycan biosynthesis
smac01100
Metabolic pathways
smac01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smac00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMDB11_0071 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMDB11_0071 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMDB11_0071 (murF)
Enzymes [BR:
smac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMDB11_0071 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Lipase_GDSL_2
Motif
Other DBs
NCBI-ProteinID:
CDG10668
UniProt:
A0ABC9ID60
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Position
86626..87987
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AA seq
453 aa
AA seq
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MIPVSLQTLAEVLSAEPIGADCQIVEVTTDTRKVTAGCLFVALKGERFDAHDFAADAVAA
GAGALLVSKRLLVDVPQLVVEDTRLALGQLGAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILRECGEVLYTAGNFNNDIGVPLTLLRLEPQHDFAVIELGANHIGEIAYTTALTRPQTAL
VNNLAAAHLEGFGSLAGVAQAKGEIFTGLPADGVAIINADNNDWPHWQSMLVGKTVWRFS
PQAAEGVDFFADNVRVNGAGTQFTLHSPFGTAEIALPLPGRHNVANALAATALAMSVGAT
LEAVRQGLKQLQAVPGRLFPVALAEGKLLLDDSYNANVGSMTAAAQVLAEMPGYRVMVVG
DMAELGAEAEECHRQVGEAARLAGVDKVISVGGLSRVLSEASGNGEHYQDKTAVIARVAE
LLSEHAVITVLIKGSRSAAMEQVVRALQEKAPC
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgatccctgtctctcttcagacactggctgaggtattgagcgctgaaccgatcggcgcc
gattgccaaattgtcgaggtgacgacagacacccgcaaggtgaccgccggttgcctgttt
gtggcgctgaaaggtgagcgtttcgatgctcacgacttcgcggcggatgccgtagccgca
ggcgccggggcattgctggtcagtaagcgcttattggtggacgtgccgcagctggtggtg
gaagacacccgtttggcgctggggcagcttggcgcctgggtgcgtcagcaggtgccggcg
cgcgtggtggcgctgaccggctcctcgggcaagacatcggtgaaagaaatgaccgccgcc
attctgcgtgaatgcggcgaagtgctgtataccgccggtaacttcaataacgacatcggc
gtgccgctgacgctgttgcgtctggagccgcagcatgattttgccgtgatagagctgggc
gctaaccacattggcgaaatcgcttacaccaccgcattgacgcgtccgcagaccgctttg
gtgaataacctggcggcggcgcacctggaaggcttcggctcgctggccggcgtcgctcag
gcgaaaggtgaaatctttaccggcctgccggccgacggcgtggcgatcatcaacgccgat
aacaacgattggccgcactggcagagcatgctggtcggcaaaaccgtctggcgcttctcg
ccgcaggccgccgaaggtgtggacttcttcgcggacaacgtgcgggtgaatggcgcaggt
acgcagttcacgctgcacagcccgttcggcaccgccgagatcgcactgccgctgccgggg
cgccacaacgtggccaacgcgctggcggccacggcgctggcgatgtcggtgggcgcgacg
ctcgaagcggtgcgtcaggggttgaaacaattgcaggcggtaccggggcgcttgttcccg
gtggcgctggccgaaggcaagctgctgctggacgacagctataacgccaacgtcgggtcg
atgaccgcggcggcgcaggtgctggcggaaatgccgggctaccgcgtgatggtggtcggc
gatatggccgagctgggcgcagaagcggaagagtgccaccgtcaggtgggtgaagccgcc
cgcctggccggggtcgataaagtgatcagcgtcggcgggttgagccgcgtgctgagcgaa
gcgtccggcaacggcgaacattatcaggacaagacagcagtgatcgcgcgcgtggcggaa
ttactgtcggaacatgcggtcatcaccgtgttaatcaaaggttcacgtagtgccgcaatg
gagcaggtagtacgcgcgttacaggagaaagcaccatgttag
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