Streptomyces malaysiensis: SMALA_3642
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Entry
SMALA_3642 CDS
T05189
Name
(GenBank) putative dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
smal
Streptomyces malaysiensis
Pathway
smal00290
Valine, leucine and isoleucine biosynthesis
smal00770
Pantothenate and CoA biosynthesis
smal01100
Metabolic pathways
smal01110
Biosynthesis of secondary metabolites
smal01210
2-Oxocarboxylic acid metabolism
smal01230
Biosynthesis of amino acids
Module
smal_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
smal_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMALA_3642
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SMALA_3642
Enzymes [BR:
smal01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SMALA_3642
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ATL83876
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Position
4658012..4659706
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AA seq
564 aa
AA seq
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MSTEPRSNHPVGSSRWATTRTQWKALGYDDEEIRRPKIAIVNSSSGLAPCFAHLDEVAEA
VRRSVYDAGGLGFEIRTVAPTDFIMAAGRGGGYVLSGRDLVSYDIEAVVEGARLDGMICL
ASCDKTTPGQLMAAARTDVPTVIVACGYQSCGVLDNGRRVDIEEVFADAGKLAAGAIGFD
DLCRMSDRAITGPGVCQGMGTANTMHIVAEALGMALPGSAPTQANSETMWAAARAAGPVV
MAAVEADRRPSTVMTPAAFRNAVTAVIAVSGSINAVKHLEAIAAESPYDIDVHRLFEEIG
RDVGPIAAVQPNGPTTIDEFDAAGGARGVLRQLGDRIDGSAITVSGTSMAEAVAGAPVDA
EVIRAEPMRPESTIVVMRGNLCPDTGIVKLSVTENRARTFRGAARVFESAPEATEAIERG
EVLPGEVLVLRGLGVTGTPGMGMASNVVFALAGSGLSERVAFVTDGQLSGLVNKGIVVGE
ISPEGGVPGPLGTVRTGDEIAIDVPNRTVDLLIDAEELNRRIEAYAETRAPRTWPTRPGS
WLGVYAGAVEPLDRGATLRRAAAN
NT seq
1695 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccgagccgcgcagtaatcatccggtcgggtcgtctcgctgggcgacgacgcgt
acgcagtggaaggcgctgggctacgacgacgaggaaatccgccggcccaagatcgccatc
gtcaactcctcttccgggctcgcgccgtgcttcgcccatctcgacgaggtcgcggaggcc
gtccgccggtcggtgtacgacgccggcgggctgggcttcgagatccgcaccgtcgcgccc
accgacttcatcatggccgccggccggggcggcgggtatgtgctctcgggccgcgacctg
gtgtcctacgacatcgaggcggttgtcgagggcgcgcggctcgacgggatgatctgcctc
gcgtcgtgcgacaagacgacgcccggccagctgatggcggccgcgcggaccgacgtcccc
accgtgatcgtcgcctgcggctaccagagctgcggtgtcctcgacaacggccgccgcgtc
gacatcgaggaggtcttcgccgatgccggcaagctcgccgcgggcgccatcggcttcgac
gacctctgccggatgtccgaccgcgccatcaccggccccggtgtctgccaggggatgggc
accgccaacaccatgcacatcgtcgccgaggcgctcggcatggcgctgcccggctcggcc
cccacccaggccaacagcgagacgatgtgggcggccgcgcgggcggcgggaccggtcgtc
atggccgccgtcgaggcggaccggcgccccagcacggtcatgacgcccgccgcgttccgc
aacgcggtgacggcggtcatcgcggtcagcggctcgatcaacgcggtcaagcatctggag
gcgatcgccgcggagtcgccgtacgacatcgatgtccaccggctcttcgaggagatcggg
cgggacgtcggcccgatagccgcggtccagcccaacgggcccacgaccatcgacgagttc
gacgccgcgggcggcgcccggggcgtgctccggcagctcggcgacaggatcgacggctcg
gccatcacggtctcgggcacatcgatggccgaggccgtcgccggtgcccccgtcgacgcg
gaggtgatccgcgccgaaccgatgcgccccgagtccaccatcgtcgtgatgcgcggcaat
ctgtgccccgacaccggaatcgtgaagctgtcggtcaccgagaaccgggcccgcaccttc
cgcggtgcggcgcgcgtcttcgagtccgcgccggaggccaccgaggcgatcgagcgcggc
gaggtgctgccgggcgaggtccttgtgctgcggggtcttggcgtcaccggcacaccgggg
atgggcatggcctccaacgtggtcttcgcgctggccggttccggcctgagcgagcgggtg
gcgttcgtgaccgacggacagctctcgggcctcgtcaacaagggcatcgtcgtcggcgag
atctcaccggagggaggcgtgccgggcccgctggggaccgtccgcaccggtgacgagatc
gcgatcgacgtcccgaaccggaccgtcgacctcctgatcgacgccgaagagctgaaccgc
cggatcgaggcgtacgccgaaacacgcgcgccacggacctggccgacgcggcccggctcc
tggctcggtgtgtacgccggggccgtggagccgctcgaccggggcgccacgctgcgccgg
gccgccgccaactga
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