Streptomyces malaysiensis: SMALA_4284
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Entry
SMALA_4284 CDS
T05189
Name
(GenBank) dihydroxy acid/phosphogluconate dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
smal
Streptomyces malaysiensis
Pathway
smal00290
Valine, leucine and isoleucine biosynthesis
smal00770
Pantothenate and CoA biosynthesis
smal01100
Metabolic pathways
smal01110
Biosynthesis of secondary metabolites
smal01210
2-Oxocarboxylic acid metabolism
smal01230
Biosynthesis of amino acids
Module
smal_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
smal_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMALA_4284
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SMALA_4284
Enzymes [BR:
smal01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SMALA_4284
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GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
ATL84517
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Position
5392185..5393972
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AA seq
595 aa
AA seq
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MQASGVAREDFGKPIVAVANSFTEFVPGHTHLQPVGRIVSEAIHAAGGIAREFNTIAVDD
GIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICISNCDKITPGMLMAAMRLNIPTV
FVSGGPMEAGEATLVDGTVRKLDLVNAISDAVNESVSDEDILRIENNACPTCGSCSGMFT
ANSMNCLTEAIGLSLPGNGSVLATHTARKALYETAGRTVVEITKRHYEQDDHTVLPRSIG
SRAAFENAMALDIAMGGSTNTILHLLAAAQEAGLDYNLEDIDEVSRRVPCLAKVAPNVAP
GGTYYMEDVHRAGGIPAILGELFRGGLLNEDVHSVHSASLADWLKTWDVRGGSPSAEAVE
LWHAAPGCKRSATAFSQSERWDSLDTDAAGGCIRDMEHAYSKDGGLAVLKGNLSVDGSVV
KTAGVDESIWTFEGPAVVCESQEEAVERILGKQVKEGDVVVIRYEGPKGGPGMQEMLYPT
SFLKGRGLGKACALVTDGRFSGGTSGLSIGHASPEAASGGTIALVQDGDRIRIDIPGRSI
ELLVSEEELAARREALGGVYAPKNRERKVSTALRAYAAMATSADKGAIRDVSLLG
NT seq
1788 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcttccggcgtagcgcgcgaggacttcggcaagccgatcgtcgccgtggccaac
agcttcaccgagttcgtgcccggccacacccacctccagccggtcggccggatcgtgagc
gaggcgatccacgcggcgggcggcatcgcgcgcgagttcaacaccatcgccgtggacgac
ggcatcgccatgggccacggcgggatgctctacagcctcccctcccgcgacctgatcgcc
gactccgtggagtacatggtcgaggcccactgcgccgacgcgctgatctgcatctccaac
tgcgacaagatcacgcccgggatgctgatggccgcgatgcggctcaacatcccgaccgtc
ttcgtgtccggcggccccatggaggcgggcgaggccacgctcgtggacggcaccgtccgt
aagctggacctggtcaacgcgatctcggacgcggtcaacgagagcgtctcggacgaggac
atcctccgtatcgagaacaacgcctgcccgacctgcggctcctgttccggcatgttcacc
gccaactcgatgaactgcctgaccgaggcgatcggcctctccctgccgggcaacggctcg
gtgctggccacccacaccgcccgcaaggcgctctacgagaccgcgggccgcaccgttgtg
gagatcaccaagcgccactacgagcaggacgaccacaccgtgctgccgcgctccatcggc
tcccgcgccgccttcgagaacgccatggcgctcgacatcgccatgggcggctcgaccaac
acgatcctgcatctgctggccgccgcccaggaggccggtctcgactacaacctcgaggac
atcgacgaggtttcgcgccgggtgccctgtctggccaaggtcgcccccaacgtcgccccc
ggcggcacgtactacatggaggacgtgcaccgcgcgggcggcatcccggcgatcctcggc
gagctgttccgcggcgggctgctgaacgaggacgtccactccgtgcacagcgcctcgctc
gccgactggctcaagacctgggacgtgcgcggcggttcgccctcggccgaggccgtcgag
ctgtggcacgcggcccccggctgcaagcgctccgccaccgccttctcgcagtccgagcgc
tgggactcgctggacaccgacgccgcgggcggctgcatccgcgacatggagcacgcctac
tccaaggacggcggactcgccgtcctcaagggcaatctgtccgtcgacggcagtgtggtg
aagaccgccggcgtggacgagtccatctggaccttcgagggccccgccgtggtctgcgaa
tcccaggaggaggccgtcgagcggatcctgggcaagcaggtcaaggagggcgacgtcgtc
gtcatccgctacgagggccccaagggcggccccggtatgcaggagatgctctaccccacc
tccttcctcaagggtcgcggcctgggcaaggcgtgtgcgctggtcaccgacggccgcttc
tccggcggcacttcgggtctctccatcggccacgcctcgccggaggcggcgtccggcggc
accatcgccctggtccaggacggcgaccggatccgcatcgacatccccggccgctccatc
gaactcctggtgagcgaggaggagctggcggcccgccgcgaggcgctcggcggtgtctac
gccccgaagaaccgcgagcgcaaggtgtccaccgcgctgcgcgcctacgcggcgatggcc
accagcgcggacaagggcgcgatccgggacgtcagcctcctcggctga
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