Streptomyces malaysiensis subsp. malaysiensis DSM 4137: SMALA_5500
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Entry
SMALA_5500 CDS
T05189
Name
(GenBank) putative alpha-isopropylmalate/homocitrate synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smal
Streptomyces malaysiensis subsp. malaysiensis DSM 4137
Pathway
smal00290
Valine, leucine and isoleucine biosynthesis
smal00620
Pyruvate metabolism
smal01100
Metabolic pathways
smal01110
Biosynthesis of secondary metabolites
smal01210
2-Oxocarboxylic acid metabolism
smal01230
Biosynthesis of amino acids
Module
smal_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SMALA_5500
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMALA_5500
Enzymes [BR:
smal01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SMALA_5500
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Ortholog
Paralog
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
ATL85730
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All DBs
Position
6758928..6760526
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AA seq
532 aa
AA seq
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MKDLPDDGFHVFDTTLRDGAQREGINLTVADKLTIARHLDDFGVGFIEGGWPGANPRDTE
FFARARAEIDFRRAQLVAFGATRKAGVRAEDDPQVKALLDSGAPVITLVAKSHDRHVELA
LRTTLEENLAMVRETVAHLRSQGRRVFLDCEHFFDGYRANPAYAKQVVAAAHEAGAEVVI
LCDTNGGMLPGQIDAVVRTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTANG
YGERVGNANLFPVVAALELKYGRRVLPEGALEEMTRISHAIAEVVNLTPSTHQPYVGVSA
FAHKAGLHASAIKVDPDLYQHIDPERVGNTMRMLVSDMAGRASIELKGKELGFDLGGDRA
LVGRIVERVKERELAGYTYEAADASFELLLRQEVDGRPRRYFRVESWRAIVEDRPDGTHA
NEATVKLWAKGERIVATAEGNGPVNALDRALRVGLERIYPQLATMELVDYKVRILEGKHG
TESTTRVLVSTADGQGEWSTVGVGGNVIAASWQALDDAYAYGLLRAGVDPQE
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgaaggatctgcccgacgacggtttccatgtcttcgacaccacgctccgcgacggagcg
cagcgcgagggcatcaacctgacggtcgcggacaagctgaccatcgcccgtcacctggac
gacttcggcgtgggcttcatcgagggcggctggcccggcgccaacccgcgcgacacggag
ttcttcgcccgggcccgcgccgagatcgacttccggcgcgcccagctggtggcgttcggc
gcgacccgtaaggcgggggtgcgcgccgaggacgacccccaggtcaaggcgttgctggac
tccggggcgccggtgatcaccctggtggcgaagtcccacgaccgccatgtggagctggcc
ctgcgcaccacgctcgaggagaacctcgcgatggtccgcgagaccgtcgcccatctgcgg
tcccagggccgccgggtcttcctcgactgcgagcacttcttcgacggctaccgggccaac
cccgcctacgccaagcaggtcgtcgccgccgcccatgaggcgggcgccgaggtggtgatc
ctctgcgacaccaacggcggcatgctccccggccagatcgacgcggtggtccgcaccgtg
ctggccgacaccggcgcccggctgggcatccacgcccaggacgacaccggctgcgcggtc
gccaacaccctcgccgccgtggacgcgggcgccacccacgtccagtgcacggccaacggc
tacggcgagcgggtgggcaacgccaacctcttcccggtcgtcgcggccctggagctgaag
tacggccgccgggtgctgccggagggcgccctggaggagatgacccggatctcgcacgcg
atcgccgaggtcgtcaatctgacgccgtccactcaccagccctatgtgggtgtttccgcc
ttcgcccacaaggccgggctgcacgcctccgcgatcaaggtcgacccggatctgtaccag
cacatcgaccccgagcgggtcggcaacaccatgcggatgctcgtctccgacatggccggc
cgggcgtcgatcgagctcaagggcaaggagctgggcttcgacctcggcggcgaccgggcg
ctggtgggccggatcgtcgaacgggtcaaggagcgggagctcgcgggctacacctacgag
gccgccgacgcctccttcgagctgctgctgcgccaggaggtcgacggccgcccccgccgc
tacttccgggtcgagtcctggcgggcgatcgtcgaggaccgcccggacggcacccacgcc
aacgaggccacagtgaagctgtgggccaagggcgagcggatcgtcgccacggccgagggc
aacggcccggtcaacgccctggaccgggcgctgcgggtggggctggagcggatctacccg
cagctggcgacgatggagctggtggactacaaggtccgcatcctggaaggcaaacacggc
accgagtccacgacccgggtgctggtctccaccgcggacggccagggggagtggtcgacg
gtcggcgtcggggggaacgtgatcgccgcgtcctggcaggccctggacgacgcctacgcc
tacgggctgctgcgggccggggtggatccccaggagtga
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