Streptomyces malaysiensis subsp. malaysiensis DSM 4137: SMALA_5524
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Entry
SMALA_5524 CDS
T05189
Name
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
smal
Streptomyces malaysiensis subsp. malaysiensis DSM 4137
Pathway
smal00470
D-Amino acid metabolism
smal00550
Peptidoglycan biosynthesis
smal01100
Metabolic pathways
smal01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SMALA_5524
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMALA_5524
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMALA_5524
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
smal01011
]
SMALA_5524
Enzymes [BR:
smal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SMALA_5524
Peptidoglycan biosynthesis and degradation proteins [BR:
smal01011
]
Precursor biosynthesis
Amino acid ligase
SMALA_5524
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Amidohydro_2
ZK643_helical
Motif
Other DBs
NCBI-ProteinID:
ATL85754
LinkDB
All DBs
Position
6785702..6786874
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AA seq
390 aa
AA seq
DB search
MSSQTPSPGPVPASSGGERRKPRVAVVFGGRSSEHAISVVTAGAVLRAIDREKYDVLPIG
ITADGRWALTADEPERMAIANRELPSVERLAESSEGSVVLPVDPGNREVVYSEPGAVPKA
LGDVDVVFPMLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGMDKEYMKRVFVSFGLPV
GPYEVIRPRAWEQEPSAARRRIVEFAEEHGWPLFVKPARAGSSIGISKVDDPADLDEAIE
EARRHDPKVIVEALLRGREIECGVLEYEDGPRASVPAEIPPVSSHAFYDFEAKYIDSADG
IVPAPLTEEQTRRVQELAVAAFEAASCEGLVRADFFLLDSGEFVINEINTMPGFTPISMY
PRMWQESGVSYPELVDRLLQAALRRSTGLR
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgagcagccagaccccttccccaggccctgtcccggcttcctccggaggcgagcggcgg
aagccgcgcgtcgccgtcgtcttcggcggccgcagctccgagcacgccatctcggtggtc
accgcgggcgccgtgctgcgcgccatcgaccgtgagaagtacgacgtgctgccgatcggc
atcaccgcggacggccgttgggcgctgaccgcggacgagccggagcggatggccatcgcc
aaccgcgagctgccgagcgtcgaacggctcgccgagtccagcgaaggctcggtcgtcctc
ccggtcgacccggggaaccgcgaggtcgtctacagcgagccgggggcggtgcccaaggcg
ctgggcgacgtcgacgtcgtcttccccatgctgcacggtccgtacggcgaggacggcact
ctccaggggctgctggagctgtccggggtgccgtatgtgggcgccggggtgctcgcctcc
gcggtgggcatggacaaggaatacatgaagcgggtgttcgtctccttcgggctgcccgtc
ggcccgtacgaggtgatccgcccccgcgcctgggagcaggaaccttccgccgcccgccgc
aggatcgtggagttcgccgaggagcacggctggccgctcttcgtgaagcccgcgcgcgcc
ggctcctccatcgggatcagcaaggtcgacgaccccgcggacctggacgaggccatcgag
gaggccaggcgccacgacccgaaggtcatcgtggaggcgctgctgcgcggccgcgagatc
gaatgcggagtgctggagtacgaggacgggccgcgggccagcgtgcccgccgagatcccg
ccggtctcctcccacgccttctacgacttcgaggcgaagtacatcgactcggcggacggc
atcgtgcccgcgccgctcaccgaggagcagacccgacgggtccaggagctcgcggtggcc
gccttcgaggcggcgtcctgcgaggggctggtccgggccgacttcttcctgctggacagc
ggcgagttcgtgatcaacgagatcaacaccatgcccggcttcaccccgatctcgatgtac
ccgcgcatgtggcaggagagcggagtgagctaccccgagctggtggaccggttgctccag
gccgcgctgcgccgctcgacagggctgcgctag
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