KEGG   Streptomyces malaysiensis DSM 4137: SMALA_6441
Entry
SMALA_6441        CDS       T05189                                 
Name
(GenBank) uroporphyrin-III methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
smal  Streptomyces malaysiensis DSM 4137
Pathway
smal00860  Porphyrin metabolism
smal01100  Metabolic pathways
smal01110  Biosynthesis of secondary metabolites
smal01120  Microbial metabolism in diverse environments
smal01240  Biosynthesis of cofactors
Module
smal_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:smal00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    SMALA_6441
Enzymes [BR:smal01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     SMALA_6441
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     SMALA_6441
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     SMALA_6441
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 2-Hacid_dh_C XdhC_C Shikimate_DH Radical_SAM F420_oxidored DUF7504
Other DBs
NCBI-ProteinID: ATL86669
LinkDB
Position
7907638..7908858
AA seq 406 aa
MSENFAYPVGLRLSGRRVVVLGAGQVAQRRLPALIAAGADILLISPSATASVEAMAEAGE
VRWERRRYREGDFEGAWYVLITTNDPEANAAASAEAEARRVWCVRSDDAEAASAWTPATG
RSEGVTVAVLTGQDPRRSAAVRDAVVEGLRDGTLAAPRHRTRGPHVALVGGGPGDPDLIT
VRGRRLLAEADVVVADRLGPRDLLDELPPHVEVIDAAKIPYGRFMAQEAINNALIEHAKA
GKSVVRLKGGDPFVFGRGMEEAEALAEAGIPCTVVPGISSSISVPGAAGIPVTHRGVAHE
FTVVSGHVAPDDPSSLVDWAALARLRGTLVLLMAVEKIGAIAAALVAHGRAADTPVAVVQ
EGTTPTQRRVDATLATVAEKVAAEGVRPPAVVVIGDVVALSARDHG
NT seq 1221 nt   +upstreamnt  +downstreamnt
atgtccgaaaactttgcgtacccggtcggactgcgcctttccgggcggcgggtcgtcgtc
ctcggggcgggccaggtggcccagcgccggctgccggcgctgatagcggccggtgcggac
atcctgctgatctcgccgtccgccacggcctcagtcgaggccatggccgaggcgggagag
gtgcgctgggagcgccgccggtaccgggagggcgacttcgagggcgcctggtacgtgctg
atcaccacgaacgacccggaggccaacgccgccgcgtccgccgaggccgaggcgcgccgc
gtctggtgcgtccgcagcgacgacgccgaggccgcctccgcctggaccccggccaccgga
cgcagcgagggcgtcaccgtggccgtgctcaccgggcaggacccgcgccgctccgccgcg
gtccgggacgccgtggtggaggggctgcgcgacggcacgctcgccgcgccccgccaccgc
acccgcggcccccatgtggcgctggtgggcggcgggccgggcgatccggacctgatcacc
gtgcgcggccgccgcctcctcgccgaggcggacgtggtggtggccgaccgcctcggcccg
cgcgatctgctcgatgaactgccgccgcatgtcgaggtgatcgacgcggcgaagatcccg
tacggccgcttcatggcgcaggaggcgatcaacaacgcgttgatcgagcacgccaaggcg
ggcaagtcggtggtccgcctcaagggcggcgaccccttcgtcttcgggcgcggcatggag
gaggcggaggcgctcgccgaggccgggatcccgtgcaccgtggtccccggcatctccagc
tccatcagcgtcccgggcgcggccgggatcccggtgacccaccggggcgtcgcgcatgag
ttcacggtggtcagcggccatgtcgcccccgacgaccccagctccctggtggactgggcg
gcgctggccaggctgcgcggcaccctggtgctgctcatggccgtcgagaagatcggcgcc
atcgccgcggccctcgtcgcgcacggccgggccgccgacaccccggtcgccgtggtccag
gagggcaccaccccgacacagcggcgggtggacgcgaccctcgccaccgtcgcggagaag
gtcgcggccgagggcgtacggcccccggcggtcgtggtgatcggagatgtcgtcgccctc
tccgcccgtgaccacgggtga

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