Streptomyces malaysiensis DSM 4137: SMALA_8367
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Entry
SMALA_8367 CDS
T05189
Name
(GenBank) isopropylmalate isomerase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
smal
Streptomyces malaysiensis DSM 4137
Pathway
smal00290
Valine, leucine and isoleucine biosynthesis
smal00660
C5-Branched dibasic acid metabolism
smal01100
Metabolic pathways
smal01110
Biosynthesis of secondary metabolites
smal01210
2-Oxocarboxylic acid metabolism
smal01230
Biosynthesis of amino acids
Module
smal_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SMALA_8367
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SMALA_8367
Enzymes [BR:
smal01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SMALA_8367
4.2.1.35 (R)-2-methylmalate dehydratase
SMALA_8367
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ATL88576
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All DBs
Position
complement(10513411..10514886)
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AA seq
491 aa
AA seq
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MAKTLYDKVFDLHAVRELGDGQYQLFVGLHLVHEATSPQAFSMLRERGLKVAYPERNIAT
ADHVIPTDTVLRPYTDELGEAMLSELERNTGAFGLRFLSPDRGEHGIVHVVGPERGLTQP
GMTIVCGDSHTTTHGAFGAVALGIGTSQVRDVLATQTVVVNRLKVRRVQIDGALGAGVAA
KDVILYVIHRLGVMGGVGYAYEFAGEVVDRMSMDERMTLCNMAVEGGARCGYVNPDETTF
AALRGRPNAPAGADWDRAVAWWRSVASDPDAPYDDVVRLDGAAIPPMVTWGINPGQAVPV
DGAVPSDRDADEETAASLRDAYAYMDVEPGQPVGGLRIDVAFLGSCTNGRVSDFLQVAEA
LERTGLRVAPGVRALAVPGSNAVREELVSRGVDAILERAGFEFRFSGCSMCLAMNPDKLV
GRELCASSSNRNFKGRQGSPTGRTMIMSPLAVAAAAVRGGIADPRSVFGTPAAPAVPVVP
AVPASRPAPAE
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atggcaaagacgctctacgacaaggtcttcgacctgcatgcggtacgggagctgggcgac
ggccagtaccagctcttcgtcggcctgcatctcgtccacgaggcgaccagcccgcaggcc
ttctccatgctgcgcgaacgcgggctgaaggtcgcctacccggaacgcaacatcgccacc
gccgaccacgtcatcccgaccgacaccgtgctgcgcccgtacaccgacgaactcggcgag
gcgatgctctccgaactggagcgcaacaccggcgccttcggtctgcggttcctctcgccc
gaccgcggcgagcacggcatcgtccatgtcgtcggtcccgaacggggcctgacccagccc
ggcatgaccatcgtctgcggcgactcgcacaccaccacacacggggcgttcggcgccgtg
gccctggggatcggcacctcccaggtgcgggacgtgctggccacccagaccgtggtggtg
aaccgtctgaaggtccgccgggtgcagatcgacggcgcgctcggggcgggcgtggccgcc
aaggacgtgatcctctacgtgatccaccggctcggggtgatgggcggtgtgggatacgcc
tacgagttcgcgggcgaggtggtcgaccgcatgtccatggacgagcggatgacgctgtgc
aacatggccgtggagggcggcgcgcgctgcggctacgtcaaccctgacgagaccactttc
gccgcgctccgggggcgcccgaacgcccccgccggcgcggactgggaccgggcggtggcc
tggtggcgctccgtcgcctccgacccggacgccccgtacgacgacgtggtgcgcctcgac
ggcgccgcgatcccgccgatggtgacctggggaatcaaccccggccaggccgtgccggtg
gacggcgcggtgccctcggaccgggatgccgacgaggagacggccgcctcgctgcgcgac
gcctacgcctacatggacgtcgagcccggccagccggtcggcgggctgcggatcgacgtg
gcgttcctcgggtcgtgcaccaacgggcgggtctccgacttcctccaggtggccgaggcg
ctggagcgcaccgggctgcgggtcgccccgggcgtgcgggccctcgccgtccccgggtcc
aacgcggtgcgtgaggaactcgtcagccggggtgtggacgcgatcctggagcgggccggc
ttcgagttcaggttctccgggtgctcgatgtgtctggcgatgaacccggacaagctggtc
ggccgcgagctgtgcgcgtcctcctccaaccggaacttcaaggggcgccaggggtcgccc
accggccggacgatgatcatgtctccgctcgcggtcgccgcggcggccgtgcgcggtggc
atcgccgacccgcgctccgtcttcgggacgcccgccgcacccgccgtcccggtcgtaccc
gccgtaccggcttcgcggccggcaccggccgaatga
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