KEGG   Streptomyces marincola: CAG99_05075
Entry
CAG99_05075       CDS       T08123                                 
Name
(GenBank) citramalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
smao  Streptomyces marincola
Pathway
smao00290  Valine, leucine and isoleucine biosynthesis
smao00620  Pyruvate metabolism
smao01100  Metabolic pathways
smao01110  Biosynthesis of secondary metabolites
smao01210  2-Oxocarboxylic acid metabolism
smao01230  Biosynthesis of amino acids
Module
smao_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:smao00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CAG99_05075
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CAG99_05075
Enzymes [BR:smao01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CAG99_05075
SSDB
Motif
Pfam: HMGL-like LeuA_dimer HCS_D2 Hib_C HNHc_6
Other DBs
NCBI-ProteinID: ARQ68300
UniProt: A0A1W7CV96
LinkDB
Position
complement(1204415..1206028)
AA seq 537 aa
MTTDDPGPWEPTDAFHVFDTTLRDGAQREGINLTVGDKLTIARHLDEFGVGFIEGGWPGA
NPRDTEFFRRAREEIDFRNARLVAFGATRRAGTDVADDPQVRALLDSEASVVTLVAKSHE
RHVRLALRTTPEENLAMVRDTVAHLRAHGRRVFVDCEHFFDGYAADPGYALDVVRAAHGA
GADVVVLCDTNGGMLPARIGAVVGDVVAGTGARIGIHAQDDTGCAVANTLAAVDAGATHV
QCTANGYGERVGNANLFPVVAALELKYDRRVLPPGSLAEMTRISHAIAEVVNLTPATHQP
YVGISAFAHKAGLHASAIKVDPDLYQHIDPELVGNSMRMLVSDMAGRASVELKGRELGYD
LDDRDLVGRIVERVKEREQRGFTYEAADASFELLLREAVHGGPQRFFRLESWRAITDQRA
DGSVDNEATVRLWAKGERVLASGEGNGPVNALDRALRSGLERTFPQLARIQLLDYKVRIL
EGRHGTQSTTRVLITTGDGTAEWSTVGVADNVIAASWQALDDAYTYGLLRAGLRPGD
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgacgacggacgatccgggcccctgggagcccaccgacgccttccacgtgttcgacacc
acgctgcgcgacggcgcgcagcgcgagggcatcaacctcaccgtgggcgacaagctgacg
atcgcccgccacctcgacgagttcggggtcgggttcatcgagggcggctggccgggcgcc
aaccccagggacaccgagttcttccggcgcgcccgcgaggagatcgacttccgcaacgcc
cgcctcgtcgcgttcggcgccacccgcagggccgggaccgatgtcgcggacgacccccag
gtgcgggcactgctcgactcggaggcctccgtggtcacgctggtcgccaagtcccacgag
cgccacgtgcgcctggcgctgcgcaccacgccggaggagaacctggccatggtccgcgac
acggtcgcgcatctgcgggcgcacggccggcgcgtgttcgtcgactgcgagcacttcttc
gacggctacgcggccgaccccggctacgcgctggacgtcgtgcgcgcggcgcacggggcg
ggtgcggacgtcgtcgtgctgtgcgacaccaacggcggaatgctgcccgcgcggatcggt
gcggtcgtcggggacgtggtcgcggggacgggcgcgcgcatcggcatccacgcccaggac
gacaccggctgcgccgtcgccaacaccctggcggccgtcgacgcgggcgccacgcacgtc
cagtgcacggccaacggctacggggagcgggtcggcaacgccaacctcttccccgtcgtc
gccgcccttgagctgaagtacgaccgcagggtgctgccgccgggatcgctggcggagatg
acccgcatctcccacgccatcgccgaggtcgtcaacctcacgccggccactcaccagccc
tacgtgggaatctccgccttcgcccacaaggccggcctgcacgcgtccgcgatcaaggtc
gacccggacctgtaccagcacatcgaccccgaactcgtcggcaactcgatgcgcatgctg
gtctccgacatggcgggccgggcctccgtggagctgaagggcagggagctcgggtacgac
ctcgacgaccgcgacctggtcggccggatcgtcgagcgggtcaaggagcgcgagcagcgg
ggcttcacctacgaggcggccgacgcgtcgttcgaactgctgctgcgcgaggccgtgcac
ggcggcccgcagcgcttcttccgcctggagtcgtggcgcgcgatcaccgaccagcgcgcc
gacggctcggtcgacaacgaggccaccgtgcggctgtgggccaagggcgagcgcgtcctg
gccagcggtgagggcaacggtcccgtcaacgccctcgaccgcgccctgcgttccggcctc
gaacggacgttcccgcagttggcccgcattcagttgctggattacaaggtccgcatcctg
gagggcaggcacggcacccagtcgaccacccgggtcctgatcaccaccggggacggcacc
gccgagtggtccacggtgggggtcgcggacaacgtcatcgcggcctcgtggcaggcgctc
gacgacgcgtacacctacggcctgctgcgcgcgggactgcggcccggcgactga

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