Streptomyces marincola: CAG99_05075
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Entry
CAG99_05075 CDS
T08123
Name
(GenBank) citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smao
Streptomyces marincola
Pathway
smao00290
Valine, leucine and isoleucine biosynthesis
smao00620
Pyruvate metabolism
smao01100
Metabolic pathways
smao01110
Biosynthesis of secondary metabolites
smao01210
2-Oxocarboxylic acid metabolism
smao01230
Biosynthesis of amino acids
Module
smao_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smao00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CAG99_05075
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CAG99_05075
Enzymes [BR:
smao01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CAG99_05075
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Paralog
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Hib_C
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
ARQ68300
UniProt:
A0A1W7CV96
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All DBs
Position
complement(1204415..1206028)
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AA seq
537 aa
AA seq
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MTTDDPGPWEPTDAFHVFDTTLRDGAQREGINLTVGDKLTIARHLDEFGVGFIEGGWPGA
NPRDTEFFRRAREEIDFRNARLVAFGATRRAGTDVADDPQVRALLDSEASVVTLVAKSHE
RHVRLALRTTPEENLAMVRDTVAHLRAHGRRVFVDCEHFFDGYAADPGYALDVVRAAHGA
GADVVVLCDTNGGMLPARIGAVVGDVVAGTGARIGIHAQDDTGCAVANTLAAVDAGATHV
QCTANGYGERVGNANLFPVVAALELKYDRRVLPPGSLAEMTRISHAIAEVVNLTPATHQP
YVGISAFAHKAGLHASAIKVDPDLYQHIDPELVGNSMRMLVSDMAGRASVELKGRELGYD
LDDRDLVGRIVERVKEREQRGFTYEAADASFELLLREAVHGGPQRFFRLESWRAITDQRA
DGSVDNEATVRLWAKGERVLASGEGNGPVNALDRALRSGLERTFPQLARIQLLDYKVRIL
EGRHGTQSTTRVLITTGDGTAEWSTVGVADNVIAASWQALDDAYTYGLLRAGLRPGD
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
atgacgacggacgatccgggcccctgggagcccaccgacgccttccacgtgttcgacacc
acgctgcgcgacggcgcgcagcgcgagggcatcaacctcaccgtgggcgacaagctgacg
atcgcccgccacctcgacgagttcggggtcgggttcatcgagggcggctggccgggcgcc
aaccccagggacaccgagttcttccggcgcgcccgcgaggagatcgacttccgcaacgcc
cgcctcgtcgcgttcggcgccacccgcagggccgggaccgatgtcgcggacgacccccag
gtgcgggcactgctcgactcggaggcctccgtggtcacgctggtcgccaagtcccacgag
cgccacgtgcgcctggcgctgcgcaccacgccggaggagaacctggccatggtccgcgac
acggtcgcgcatctgcgggcgcacggccggcgcgtgttcgtcgactgcgagcacttcttc
gacggctacgcggccgaccccggctacgcgctggacgtcgtgcgcgcggcgcacggggcg
ggtgcggacgtcgtcgtgctgtgcgacaccaacggcggaatgctgcccgcgcggatcggt
gcggtcgtcggggacgtggtcgcggggacgggcgcgcgcatcggcatccacgcccaggac
gacaccggctgcgccgtcgccaacaccctggcggccgtcgacgcgggcgccacgcacgtc
cagtgcacggccaacggctacggggagcgggtcggcaacgccaacctcttccccgtcgtc
gccgcccttgagctgaagtacgaccgcagggtgctgccgccgggatcgctggcggagatg
acccgcatctcccacgccatcgccgaggtcgtcaacctcacgccggccactcaccagccc
tacgtgggaatctccgccttcgcccacaaggccggcctgcacgcgtccgcgatcaaggtc
gacccggacctgtaccagcacatcgaccccgaactcgtcggcaactcgatgcgcatgctg
gtctccgacatggcgggccgggcctccgtggagctgaagggcagggagctcgggtacgac
ctcgacgaccgcgacctggtcggccggatcgtcgagcgggtcaaggagcgcgagcagcgg
ggcttcacctacgaggcggccgacgcgtcgttcgaactgctgctgcgcgaggccgtgcac
ggcggcccgcagcgcttcttccgcctggagtcgtggcgcgcgatcaccgaccagcgcgcc
gacggctcggtcgacaacgaggccaccgtgcggctgtgggccaagggcgagcgcgtcctg
gccagcggtgagggcaacggtcccgtcaacgccctcgaccgcgccctgcgttccggcctc
gaacggacgttcccgcagttggcccgcattcagttgctggattacaaggtccgcatcctg
gagggcaggcacggcacccagtcgaccacccgggtcctgatcaccaccggggacggcacc
gccgagtggtccacggtgggggtcgcggacaacgtcatcgcggcctcgtggcaggcgctc
gacgacgcgtacacctacggcctgctgcgcgcgggactgcggcccggcgactga
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