Serratia marcescens SM39: SM39_0071
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Entry
SM39_0071 CDS
T03592
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smar
Serratia marcescens SM39
Pathway
smar00300
Lysine biosynthesis
smar00550
Peptidoglycan biosynthesis
smar01100
Metabolic pathways
smar01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smar00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SM39_0071 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SM39_0071 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SM39_0071 (murF)
Enzymes [BR:
smar01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SM39_0071 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Lipase_GDSL_2
Motif
Other DBs
NCBI-ProteinID:
BAO32141
UniProt:
A0AAT9DUK1
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Position
86635..87996
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AA seq
453 aa
AA seq
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MIPASLQTLAEVLSAELIGADCQIVEVTTDTRKVTAGCLFVALKGERFDAHDFAADAVAA
GAGALLVSKRLLVDVPQLVVQDTRLALGQLGAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILRECGEVLYTAGNFNNDIGVPLTLLRLEPQHDFAVIELGANHIGEIAYTTALTRPQTAL
VNNLAAAHLEGFGSLAGVAQAKGEIFTGLPADGVAIINADNNDWPHWQNMLGGKTVWRFS
PQAAEGVDFFADNVRVNGAGTQFTLHSPFGTAEIALPLPGRHNVANALAATALAMSVGAT
LEAVRQGLKQLQAVPGRLFPVALAEGKLLLDDSYNANVGSMTAAAQVLAEMPGYRVMVVG
DMAELGAEAEECHRQVGEAARLAGVDKVISVGGLSRVLSEASGNGEHYQDKTAVIARVAE
LLSEHAVITVLIKGSRSAAMEQVVRALQEKAPC
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgatccctgcctctcttcagacactggctgaggtattgagcgctgagctgattggcgcc
gattgccaaattgtcgaggtgacgacagacacccgcaaggtgaccgccggttgcctgttt
gtggcgctgaaaggcgagcgtttcgacgctcacgacttcgcggcggatgccgtagccgca
ggcgccggggcgctgctggtcagtaagcgcttattggtggacgtgccgcagctggtggtg
caagacacccgtctggcgctggggcagcttggcgcctgggtgcgtcagcaggtgccggcg
cgcgtggtggcgctgaccggctcctcgggcaagacatcggtgaaagaaatgaccgccgcc
attctgcgcgaatgcggcgaagtgctgtataccgccggcaacttcaataacgacatcggc
gtgccgctgacgttgctgcgtctggaaccgcagcatgattttgccgtgattgagctgggc
gctaaccacattggtgaaattgcttacaccaccgcattgacgcggccgcagaccgctttg
gtgaacaacctggcggcggctcacctggaaggcttcggctcgctggccggcgtcgcgcag
gcgaaaggtgaaatctttaccggcctgccggccgacggcgtggcgatcatcaacgccgat
aataacgactggccgcactggcagaacatgctgggcggcaaaaccgtctggcgcttctcg
ccgcaggccgccgaaggcgtggacttcttcgcggataacgtgcgggtaaacggcgcaggc
acgcagttcacgctgcacagcccgttcggcaccgccgagatcgcgctgccgctgccgggg
cgccacaacgtggccaacgcgctggcggcgacggcgttggcgatgtcggtgggtgccacc
ctcgaagcggtgcgtcaggggctgaaacagctgcaggcggtgccggggcgtctgttcccg
gtggcgctggccgaaggcaagctgctgctggacgatagctataacgccaacgtcgggtcg
atgaccgcggcggcgcaggtgctggcagagatgccgggctaccgcgtgatggtggtcggc
gatatggccgagctgggcgcggaagcggaagagtgtcaccgtcaggtgggcgaagccgcc
cgtctggccggcgtcgacaaagtgatcagcgtcggcggtttgagccgcgtgctgagcgaa
gcgtccggcaacggcgaacattatcaggacaagacagcagtgatcgcgcgcgtggcggaa
ttactgtcggaacatgcggtcattaccgtgttaatcaaaggttcacgtagtgccgcaatg
gagcaggtagtacgcgcgttacaggagaaagcaccatgttag
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