Serratia marcescens SM39: SM39_4246
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Entry
SM39_4246 CDS
T03592
Symbol
fadB
Name
(GenBank) fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
KO
K01825
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
5.3.3.8
]
Organism
smar
Serratia marcescens SM39
Pathway
smar00071
Fatty acid degradation
smar00280
Valine, leucine and isoleucine degradation
smar00310
Lysine degradation
smar00362
Benzoate degradation
smar00380
Tryptophan metabolism
smar00410
beta-Alanine metabolism
smar00640
Propanoate metabolism
smar00650
Butanoate metabolism
smar00907
Pinene, camphor and geraniol degradation
smar00930
Caprolactam degradation
smar01100
Metabolic pathways
smar01110
Biosynthesis of secondary metabolites
smar01120
Microbial metabolism in diverse environments
smar01200
Carbon metabolism
smar01212
Fatty acid metabolism
Module
smar_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
smar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SM39_4246 (fadB)
00650 Butanoate metabolism
SM39_4246 (fadB)
09103 Lipid metabolism
00071 Fatty acid degradation
SM39_4246 (fadB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SM39_4246 (fadB)
00310 Lysine degradation
SM39_4246 (fadB)
00380 Tryptophan metabolism
SM39_4246 (fadB)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
SM39_4246 (fadB)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
SM39_4246 (fadB)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
SM39_4246 (fadB)
00930 Caprolactam degradation
SM39_4246 (fadB)
Enzymes [BR:
smar01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
SM39_4246 (fadB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
SM39_4246 (fadB)
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
SM39_4246 (fadB)
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.8 Delta3-Delta2-enoyl-CoA isomerase
SM39_4246 (fadB)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
BAO36176
UniProt:
A0AAT9F3X7
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All DBs
Position
4416466..4418655
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AA seq
729 aa
AA seq
DB search
MLYQGETLQLHWLDNGIAELVFNAPGSVNKLDTRTVASLGEALTVLENQPELKGLLLRSS
KAAFIVGADITEFLSLFAAPAEKLQEWLVFANNVFNRLEDLPVPTISAINGYALGGGCEC
ILATDFRVASPDARIGLPETKLGIMPGFGGSVRLPRLLGNDSALEIIAAGKDVSAKEALK
VGLVDAVVAPEKLAEAALNMLQQAIDGKLDWRAARQPKLEPLKLSPIEAAMSFTTAKGMV
LQTAGKHYPAPMTAVKTIEAAAKLGRDEALKLETASFVPLARSNEARALVGIFLNDQFVK
GQAKKLAKNVDAPKQAAVLGAGIMGGGIAYQSALKGVPVIMKDISDKSLTLGMSEAAKLL
NKQLERGKLDGLKMAQVLSTIQPTLDYAGIERAQVIVEAVVENPKVKAAVLSEVETLIGE
DTVLASNTSTIPINHLAKSLKRPQNFCGMHFFNPVHRMPLVEIIRGEQTSDDTIAKVVAY
ASRMGKTPIVVNDCPGFFVNRVLFPYFAGFSLLLRDGADFRQIDKVMEKQFGWPMGPAYL
LDVVGIDTAHHAQAVMAAGFPDRMSKDYRDAIDVMFDNQRFGQKNQLGFYRYSQDSKGKP
RKDNDEQTDALLAEVSQPRQTISDEEIIARMMIPMINEVVRCLEEKIVASPAEADMALVY
GIGFPPFHGGAFRYLDTLGTANYVELAQRYAHLGALYQVPAGLRAKAERNESYYPVATPL
SDVATRQPA
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgctctaccaaggcgaaacattacaactgcactggctcgataacggcatcgccgagctg
gtgttcaacgcaccgggctcggtcaacaagctggacacccgcaccgtagccagcctgggc
gaagcgctcaccgtgctggaaaaccagcctgagctgaaagggctgctgctgcgttcctcc
aaagccgcgtttatcgtcggcgccgatatcaccgaattcctttctctgttcgccgcaccg
gctgaaaagctgcaagagtggctggtgttcgccaacaacgtctttaaccggctggaagat
ttaccggtgccgaccatttcggccattaacggctatgcgctcggcggcggttgcgaatgc
attctggcgaccgatttccgcgtcgcctcaccggacgcgcgcattggcctgccggaaacc
aaattgggcatcatgccgggattcggcggttccgtccgcctgccgcgcctgctgggtaac
gacagcgcgctggaaatcatcgccgccggcaaagacgtcagcgccaaagaggcgctgaaa
gtcggcctggtggatgcggtggtggcaccggaaaaactggccgaagcggcgctcaacatg
ctgcaacaggcgatcgacggcaagctggactggcgcgccgcgcgtcaacctaagctggag
ccgctgaaactcagcccgattgaagcggcgatgagctttaccaccgccaaaggcatggtg
ctgcagaccgccggtaaacattacccggcgccgatgaccgcggtgaagaccattgaagcc
gccgccaagctgggccgcgatgaagcgctgaaactggaaaccgccagcttcgtgccgttg
gcgcgttccaacgaagcgcgcgcgctggtcggcatcttcctcaacgatcagttcgtgaag
ggccaggcgaaaaagctggccaagaatgtggatgcgccgaaacaggcggcggtgctgggc
gccggcatcatgggcggcggcatcgcttaccaatcggcgctgaaaggcgtgccggtgatc
atgaaagacatcagcgacaagtcgctgacgctgggcatgagcgaagcggccaagctgctc
aataagcaactggaacgcggcaagctggatggcctgaaaatggcacaggtgctgtcgacc
attcagccgacgctggactacgctggtatcgaacgcgcgcaggtgatcgtcgaagcggtc
gtcgagaacccgaaagtcaaagccgccgtgctgtcggaagtggaaaccctgatcggtgag
gacaccgtgctggcgtcgaacacctcgaccattccgattaatcacctggcaaaatcgctg
aagcgcccgcaaaacttctgcggcatgcacttctttaacccggtacaccgcatgccactg
gttgaaatcattcgcggcgaacagaccagcgatgacaccatcgccaaggtggtggcctac
gctagccgcatgggcaaaacgccgatcgtggtgaacgactgcccgggcttcttcgtcaac
cgcgtgctgttcccgtatttcgccggcttcagcctgctgctgcgcgacggcgccgacttc
cgtcagatcgataaagtgatggaaaaacagttcggctggccgatgggcccggcctacctg
ctcgacgtcgtgggcatcgacaccgcgcatcatgcgcaggcggtaatggccgccggcttc
ccggatcgcatgagcaaagactaccgcgacgccattgacgtgatgttcgacaaccagcgc
ttcggtcaaaaaaatcagctgggcttctaccgctacagccaggacagcaaaggcaagccg
cgcaaggacaacgacgagcagaccgatgcgctgctggccgaagtgagccaaccgcgccag
accatcagcgacgaagaaatcatcgcgcgcatgatgatcccgatgatcaacgaagtggtt
cgctgcctggaagagaagatcgtcgccagcccggcggaagccgatatggcgttggtctac
ggcatcggcttccctccgttccacggcggcgcattccgctacctggatacgctcggcacc
gccaactacgttgagctggcccagcgttacgcacacctcggcgccctgtatcaggtgccg
gccggtctgcgcgccaaggccgaacgcaatgaaagctactacccggtggcgacaccgctg
tccgacgtcgctacccgccaaccggcatga
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