Scophthalmus maximus (turbot): 118283342 Help Entry 118283342         CDS       T09850                                  Symbol dst Name (RefSeq) dystonin isoform X1   KO K10382   dystonin Organism smau  Scophthalmus maximus (turbot) Pathway smau04382   Cornified envelope formation Brite KEGG Orthology (KO) [BR:smau00001]  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     118283342 (dst)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:smau04812]     118283342 (dst) Cytoskeleton proteins [BR:smau04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     118283342 (dst) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin SR_plectin_7 CH Spectrin_2 Spectrin_3 GAS2 SH3_10 Spectrin_SYNE1 EF-hand_6 EF-hand_7 Spectrin_4 EF-hand_1 Spectrin_1st_PEPL EF-hand_5 Motif Other DBs NCBI-GeneID:  118283342 NCBI-ProteinID:  XP_047191313 LinkDB All DBs Position 10:13647322..13748393 Genome browser AA seq 8420 aa AA seqDB search MIAAAFLVLLRPYSIQCVLLLLLLLLGTIATILFFCCWHRRLRDGKHPMKSVLSGRAKSR VGLRTHHFRSEGFRHSPRHARRSIHARVAEEKPNLVEIPESEPDSSSTLRKRKVKKRVPP EFYQSVQVTPTRRPSSSSGNPSLHGSMSSSADFSDEDDYSVKSGSASPAPGDTLPWNLPR HERSKRKIQGGSVLDPAERAVLRIADERDRVQKKTFTKWINQHLLKVRKHINDLYEDLRD GHNLISLLEVLSGDTLPRERDFLKTLRLVSGTEACAVEQHGDTVDDDKGPRERGRMRFHR LQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISEIHVTGESEDMT AKERLLLWSKQITDGYVGVRCANFTTSWRDGRLFNAIIHKYRPDLVDMSHVSTQSNRSNL EHAFCMAEQLGVARLLDPEDVDVQSPDEKSVITYVSTLYDAFPKVPDGVDGINANDVDIK WVEYQNMIKYLSQWIKHNVAIMSDRSFPNNPVELKALYTQYLQFKEHEIPLKENEKTKIE NLYKMLEMWIEFGRIHLPQGHHPNDVEKEWGKLIVAMLEREKSLRPEVERLEMLQQIANR VQRDCVNGEDKLALAWTALQSDAKRLESGIQFLHEAEIAGYLLECENILRQQVVDIQLLL DGRFPFADQLVQRVSKLRDDLLTLRAECSSVYSQGRTLTTEQTKMMISGITQSLNSGFSQ NMGTNLTPALTPALTPGGIATPGSPFTSSLTPCLTPSLTPGLQPPSVQCYMGSGGGGGGG GGMDPGSLRHLKHMQIRKPLLKSSLADPNMTEEEVNMKYVQDLLMWVEDMQVQLDRSEWG SDLPSVETHLDNHKSVHRAIEEFQMSLKDATLSEIQMTIPLKLSYSDKLNKLEKQYERLL SCSRERQSHLENLLDFVSQATQELIWLNEKEEEEVAFDWSDRNSNISKKRDYHADLMREL DEKEVVIKSVQDKAERLMFKNHPAKTTIEAYRAAMQTQWSWILQLCSCVERHLKENAVYF EYFRDAKESIDYLKSLQDAIQRKYSCDRTSSLHRLEDLIQESMDEKEQLLQYRSAVAGLV GRAKNIVQLRPRNPESPVRSSIPVKAICDYRQIEITIYKDDECVLASNSHRAKWKVINPA GNEAMVPSVCFTVPPPNKEAVDKATRTEQLYQNVLALWHHSHINMKSVVSWHYLMADVRA IRNWNVASIKTMLPGEHQQVLSNMQSHFDEFLEDSEESEVFTVADCAQLEGDVTACKEYY QELLRSAEREEHEESVYNNYISEIRNFRMHLEAHEEHLIRQIRTPLERDDLEQSLQRITE HERKTAELNKVKEDLDVMKEKCELFLRQAAGSSSVPTLSSELTVLVQSMSQVYSMSSIYM DKLKTVSLVVKHSQSAEALVKAYESKLYEEDAMNSEVKSIETVISTLKQWRTEIDEKQEV FHDMEDELQKARAISDRMFKAHNERDFDLDWHKEKADQLSERWQNIHSQIDCRLRDLDGI DKSLKHYRDSYSILDEWVREMEVAQLKAQENKPEDSKALAELLNKQKVLVAEIEQKQSRI DECQKYSEQYSSAIKDYELQLMTFRAMVDSQHKSPLKKRRMQSSSDAIQQEFMDLRTRYT ALVTLMTQYVKFASETLKRTEDEERSVDEEKREHGDKVSKLLHWMKQSLNNDGNAMKDSN ANTDASNKPQVSVEEMVTKKEQIAEALRATQMMLNKHSDKMTEEEREKAQEQLMALNQAY SELSQQCSDQTTSAEEDFKPSDRMDGLRTETKSPLTDQMTWNTLPEAQLMTCDALRQDLV YKPTPNHLSELNDAKKCIQSPDVSSVSLSDIAAAREGPTFEDLVMKMIEVKQVCDGVEVC YTGDTLTIERAFHSGLIPACVYVNILQRQKTCQEMINHSSPENVSLVEPEHEFEPCKVNQ LILKCLSRNKPLTPGRNVSTLRSVCDGLSDQETLSRLLGAQLDADGNENGDRLKVDAAIQ CDLMSSSSTLTVLGNQQQFMGLVLPHSGEIQTVSTSFHYHEQLTTNEYTSSLFSDRQKIA AFYIPENSEIVDIASAIENSLTDNYTTEVLKSIELPDVFPDVDHLYEKFSSWLMYKKLTV DGCHRAAESIKVDNIPSTTEARQMFISYLMMNSFIDPKSGQRVLILDRQLNETVKIFLED LVLSENTENNVSSLTVTDVPEQLDIPLLINEETEGLMKNAQYTYDPNDFVSSVDGRINFN ESTDHTFYPQNLVSSGNGKITFDKNTDHTFHGLDCVSLGNGTITFDENTDQNVDPRDFGA SIDGRITLEEKTQHLSDPCDFVFSVEERITFDEKTQCTFDSHNFGSSVDGRITFDEKTQH VFDPSDFVFSVAERITFDEKTQHTCDPHDFGSSVDGRFPYDEDTDYTFQPHDFGSSVNGR IALDEKTQHFYLRDFVSSVDDRITFDEKNQHTCNPHDLSATVDGRIAFDENTNHTFDPDD FGSSVDGMVTVDENTDHTCDPHDVGSSIDGRIIVDEKTHHAFDPHEFGSSLDGRNIFDEK SQHTCDPHDFGSSVDGRISFDKNTDHTFNLDDFGSSVDGRITLDEKTQHLYDACEFVSSV DVRIMFDEKTHHTGDLHDFGSSVDGRITIDENTDHMFDPHDFGSSVDWRFTVDENTEHTF DPHDSGSSVDGRITVDENTEHTFDPHDFVSSVDGRIIFDEKTQHTFDPHDFGSSVDGSIT FDEKTHHTGDLHDFVSSVDGRITIDENTDHTFDPHDFGSSVNWRFTVDENTEHIFDPHDF GSSVDGRITVDENTEHTFDPHDFGSSVDGRITLDEKTQHLSDACDFVSSVDGRIIFDEKT QHTFDPRDFGSSVDGSITFDEKTHHTGDLHDFGSSVDGRFTVDENTDDAFDPRDFGSSVD GRITVDENTDHAFDPRDFGSSVDGRITVDENTDHAFDPRDFGSSVDGRITLDENTDHAFD PRDFGSSVDGRITVDENTDHTFDPRDFGSSVDGRITLDENTDHTFDPRDFGSSVDGRITV DENTDHTFDPRDFGSSVDGRITLHEKTQHLSDAWDFVSSVDGRIIFDEKTQHTFDPHDFG SSVDGRITVDENTDHTFDPHDFGSSVDGRITVDENTDHTFDPRDFGSSVDGRITLDENTD HTFDPRDFGSSVDGRITVDENTDHTFDPRDFGSSVDGRITLHEKTQHLSDAWDFVSSVDG RIIFDEKTQHTFDPHDFGSSVDGRITVDENTDHTFDPHDFGSSVDGRITVDENTDHTFDP HDFGPSVDGRITVDENTDHTFDPQDFVSSVAGSTTFNDFEGFSDTTDPGVAEKNKKSGEV GERICANSLQTDVGGAVIEDLDIPASVVMSVFPILSSVKSTNVGSLSKMSDSECSGKSCS QTIDHFNAESVCSESRTIDTNLAEFLCSEDLVEERGILDVTSGRCYDMNTTYNKGLVDET ATLKLRDLQSDEKGSVVGVEEGSMSVLKQVLSDESILSNIDLPTMKERRLFSSDCTVSIH ESLQPRLVTDAANLDSKTGIYPEENCSQSISVDQNLGLININQAENRQGSTEQKVAAVVL DFKKEEGDKESESALDCVTRGNIDDEMSNYLHNSPPPARGHELPVISPTSWSQVTAECVH HTDKCPSLPEDTDSQVLINCQLTERADLSSCVMENAALTTHSRQSSLHDRTCNSNTDPEN QTYHSCKPDSSPIPNDFLITGYNSPLGNQTLSKSDKDKSTSHCTVLSEESRLENDTVQSP LDNEPTPSLYYSSPRDLVESAITSVSWGDCNYDENIADDGSTSTLPQQAVLHSESDFSSG SEPRCFQEGQTSRPPVVSSEITTSDTGNHGSCDIKNSRHYTSTSTRVSLETLELTNNDSF DSKHSGADEAEPHSEMFSPESQHKDIFSHSEQISVSGNEIENAHKNDGSECCLNPRSESS NVNSGRSETRMKDGLGSVTVPDRNSLDLYASEYPQIVSDFLSDGSNSSAVASSAPAVFSN DVRTCVDDQEEMGTNVSDLSPTLLNTESPVAIVQKTQQPLGEGDFHERDMHHGLLKSSHS GLPVDFLEQSTPSLNNKEQESVSILQEERVHEEKQQSHAPNIQLQLLQVLKTVSPSQDLS MLQEVMETLNSALGGDSQEDRQHTLESIKEESSEGGVEGPDGHIPSPLSSADSDACKVEE FKNQLFSIQDFLECVGRLQDHSDVLDDARKDLLVQAPVGNNMEELQIQIEECECLESQLS RLAGDLAVDVEKAKCLLSSADDHIPVQIQQDLASIYLEVGPNLTAASQLCAEQIQSLNQA LETERVHLDSMYQKHLRDLDELASLIQNDSEMQCLDLNTCDVDTLKHLIQQNKDAECNLL KETRLKLEDVTFDIQCFISEQAQFLSAAQSSCLLKLLSTTQRTLRDQTERLVAERSSLDV LLDTRERQNHAESLLERHKEFTEKLEEVCDNLTLTENRLIGHQQQTDSAESVTDLQQYQQ EHQALQKDVLTNASALNEVITSTKKFLEENRNKLTPDQIAIAESKLEEAKSKAKLINQRA EESRKDLEKVVTTAIKQESEKAAAVERLEESKNKIEGLLDWISNIGSEKESGLDQTDHIS KENGNLPEETSAKGLMGENDDANGNALQSTGNDFGREARGESDASLDLDKQYDRVKAHHQ EILSQQQDLIMATQSAQALLDKQADVLSAEEKEKLQRNIQELKGRYEASLTQAEQQMKQV HCVQEELKKFQDDCEEFGGWLDQAEGEMEELGAPAGSLNILSDKLQRQKSFSEDVISHKG DLRFITISGQKVLDVAKACGLGDPAAKNAQLHVDTSGTCSAVKEKLDSAAGRYKTLHSQC NQLGNNLKDVVDKYKKYDDSSAGLLKWLNSSEEEARKQQSEAIAADPQTLQKQLEETKAL QGQMTGHQTAVDTLRKTTESLVTCEGDLLSNPDEIQETVDDIVERYDNLSKSVSDRNEKL QITLTRSMSVQDGLDEMMAWMEGVEASVKEKGQIPLDSASIGDILSKEAALEQDIASRQS SISAMKDKVKKFAETADSSAAALLQSNMEALSQRFSDACDKHKQKVSQLEQLKEKVEQFE TVAGKVQQFVVKRSQDLHETDGPGKTFNELSQLMQSTKAEMAEHASDVEKLQTLSKELSE LSPDGNKAQIQSKMDNLLNIFTTFKDTVKEKEEEVSSCQDQLGEFRSAANALTKWLEETN EKVPAVQPSSSEKSLEKDLQTVTGLLDEWTSKGPAVQDLNSEGSALCSLITFLTSPAKTK TPNKSALTNGGGGGPASHSYLTNKELMVIQQNVSFVNEGYASLGETLKSRATELSSSVQY VKEAQKETADMMTWLKDMKKTAASWNNAATEKESVKTQLEQQKAFEDDMKQKQERHQKLR EKLLNLIKTHPNSPEAAKWKQMLAEIDAAWTDISGSVEQRKQHLEQSNKNLDIFQTTELQ LGQWLSEKELMMSVLGPLSIDLNMLKMQKQQVQILQNEFKSRKPQYEQLEEAASAILSSS GNQDPSNGKLVREKLAAITQKWQGITGQLDQRDSLIDQAVVKTGQFQELLRSLGHTASQL ENQLTNHQGHSTQPDAVKKQLEDVHNISAQLREERKTLKEAEAINTELTAMVTEDYLKAD LARQLESVSKPFKQLEEKAAKRIEQLNSTFASSQQFHQTSKDFQSWLGEKLQDQSKPQAI SAKVDILHQTLEEHSKLQQALGEHEEVYNTILGEGEMLLQSTDGAEKLALQGQLTALSSN WDEVKRSSVEQAGKLQTALQRSLKYQEHAEKLSSWIQECEASEGRVKLTVDPAAVESSIS QVKVLQKDVDKSRRLVEQLDTAADSLLEVANVDTQAVKEEKASIGKRVDNVAEGLQSKRE SLEMISHTVKEFNDTYKEAKGQLERAKKQVDAYKSQGVQGHSNKNLTNMKAQHKSLEGVQ NQIEHLKSMAKDLVVNVPDADGVTDLLLHTDSIENDYSSLNKILEETCQVLEGKLQGIGQ FQISIREMYTHFTDLDDELDSMAPVDLDLATLSEQRGSIQSFVAKLQDLMANTANAGDSC KKMLETETSPDLLGLKRDLDALSKQCGKLSDRAKGREVQVQSTFAKLEELYGKLHRMEDE LCRAVDKEATQGAVGMETDVINQQLEAFKAFQKEDIDPLQTQLQDINSLGQGLIQNAAKG TSTKKLDDDLEGVNTKWNTLNKKIAERSAQLHEALLHCGRFQDALESLLSWLTDTEELVA NQKPPSAEFKVVKAQIQEQKLLQRLLDDRKPTVELIKKEGGKVAELAESVDKEKVAKEIE CLGQRWDALLKKAENRHKQLESILVVTQQFHETLEPLSEWLAATEKHLANSEPTGTETSK LQDQICQHKALEEEIMNHSKDLFQAVSLGQVLRTVSSVDDKEFVQSKLDAAQASYIELQE RCRRKAEMLQQALANARLFGEDEVALMNWLSEVHVRLGEVSVEDYKIDVLEKQLAEQRGL QSDIELRKRNVDQAISNGMELLKQTTGDEVVVIQGKLDGIKAKYAEINSMSDNVLKTLER VLSFSSKLHHNHEDLSSWLEKVEAEIRAFADQEPVGDQLIHAQSRQKALLKETKDQKPVM DKLNELSSSLLDLIPWHTREGLDKLVTDDNERYRAVCDTITQQVDQINADILKSQQFEQA ADTELSWLTEAERKLLSMGEIRLEQDQNAAQLQAQKIFSMDVMRHKDAVDEIVKNGKAIM NSKNPEEKEKLKAKTQTLLEKYGTVSQLNSERCLQLERTQSLASQFWETYEEMWPWLQET LSTFSQLPPPSIEYDRLRQQQEELRQMRELIAEHKPHIDKMNKTGPQLLELSPVEGVPIR EKYTATDQLYIQLKADVKQRAATLDEAISKSTQFHDKIDPMLESLERIAERLRQPPSISV EVDKIREQITENKAVYVDLEKLQPSYETLRQRGEEMIARSEGADKDIYAKAVQDQLDQMV FLWSDIQALLVEREAKLLDVMDLADKFWCDHCALIVTIKDSQDLLRELEEPGVDPSVVKQ QQEFVEGFKEEIDGLQEELDVVQNQGAELMTACGEPDKPVIKKSIDEVNSAWENLNKTWK ERGERLEEAMQAAVQFQDGLQGMFDWVDIMESKLDSMSPVGTDLETVKQQIVELKEFKGE SYQLQIEMERLNHQAGLLLKKVTEEADRCEIQEPMSELRMLWENLDEKIISRQHKLEGGL LALGQFQHALDELLAWMSHTEELLDEQRKAGGDPKAIEIELAKHHVLQVDVLAHKATVET VNKAGTDLVESSAGEEAAGLQTKLENLNQRWKAIQEKTKQRKQQLESSLLQAQGFHGEIE DMQQWLKDTERQLLASKAVGGLPDTAREQLNAHLELCSALEAKEELCQELLNKGHQLLAM TPEGPDSNTEQDLANLREKWEAVQGKVAERKAKLEEALTLATDFHNSLQDFINWLTQAEQ TLNMVSPASLILETIMFQIDEHKVFVTEVNSHREHIIELDKTGTHLKYFSQKQDVVLIKN LLLSVQGRWEKVVQRSVERGRLLDDSRKRAKQFHETWNKLMEWLDESEKTLDSEVEIAND PDKIKTQLAQHKEFQKALGSKHSVYDTTARTGRALKDKTSLQDDNQKLDDMLSELRDKWD TVCGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDLVLNLIDN HKAFQKELGKRTVTVQALKRSARELVDSSHADSSWVKVQMQELSTRWETVCNLSVSKQAR LEQALCQAEEFHSTVHILLEWLAEAEQSLRFHGSLPDDEEALRALIEQHKEFMKKLEEKR VALNKATSMGEAILSICHPDSITTIKHWNTIIKARFDEVQAWARQHQQRLATALTEMLAT QDLLENLLTWLQWAETNLNDKDNEPLPQELEEVKGLIAEHQAFMEEMTRKQPDVDTITKT HKRKAAVEPQIQSHIPVLEKGRTGRKRSPTQTMYASATQAPIETKNPRVNLLVTKWQHVW LLALDRRRKLNDGLDRLEELKEFANFDFDVWRKRYMRWMNHKKSRVMDFFRRIDKDQDGK VTRQEFIEGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPLTDAD KIEDEVTRQVAKCKCPKRFQVEQIGANKYRFYLGNQFGLVHCLHDSLIGDETIAIRENQN LTPHLNVAVLESCILFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGS KMLRSESNSSITQSPIGWHISHLLSLLHEPESAKGRTNLELREKFILPEGTTQVMASFRY RGRRSRPSSRGASPNRSTSSQSCPVPPNPVLTSTPKTPQHITRNYDKPWLTNSKPSTPLK SSDSFESQGSSSEMTPVHGSKLRLPGYLSGKGFQSGEEGTLISAAVLKARTQTIGESRRN SSRPGSKAGSRGSSRRGSDASDFDISDIQSVCSDASETVGESARATPRSASRQRGGKPSK IPTPQRRTTPTSKLAKGSKR NT seq 25263 nt NT seq  +upstreamnt  +downstreamnt atgatcgccgcggcgttcctggtgctgctgaggccgtacagcattcagtgtgtcctgctg ctgctgctgctcttgctcgggaccatcgccacgatcctgtttttctgctgctggcatcgc aggctccgcgatgggaagcacccaatgaaatcggtgctctccggacgcgcaaagagccgc gttggcctccgaacgcaccattttcgatcagagggcttcaggcacagtccacgtcacgcg agaaggagcatacatgctcgggtggccgaggaaaaacccaacttggttgagatccctgag agcgagccggattcatcatccaccctcaggaaacgcaaagtgaagaagagagtcccaccc gaattttaccagtctgtacaagtcacgcccacacgcagacctagctccagctcggggaac ccgtccctccacggctccatgtcctcctcggcggatttctccgacgaggatgactacagc gtcaaatccgggtcggcgtcgccggcccccggggacactttgccctggaacctgcccaga cacgagcggtccaagaggaagatccagggagggtccgtgctggatccggcggagagagcg gtgctccggatcgcagatgaaagagacagagtgcagaagaagacgtttacaaaatggata aatcagcatctgctgaaggtacggaagcatataaatgacctgtatgaagacttgagagat ggacataacctgatctcactgctggaggttttgtccggagacacattgccaagggagcgc gattttctgaagacattgcggttggtgagtgggacagaagcatgtgcggttgagcagcat ggagacacggtggatgatgataaggggcctcgggagagagggaggatgcgcttccacaga ctccagaatgtacaaatagcgctggactatttaaagaggcggcaggtcaaacttgtgaat atccggaatgacgacatcacagacggtaacccgaaactgaccctgggactgatctggacc ataattctgcactttcagatctcggagatccatgtgacaggggagtccgaggacatgaca gccaaggagaggctgctgctctggtccaagcagataacagatggctacgtgggtgtacga tgtgccaacttcaccacctcttggagggacgggaggctctttaacgccatcattcataag tacaggccagacctggttgacatgagtcatgtgtcgacgcagagcaaccgatcaaattta gagcacgcgttttgtatggctgagcagctgggggtggccagactgctggaccctgaggac gtagatgttcagtctcctgacgaaaaatccgtcatcacctacgtctcgacgctgtacgat gccttccccaaagtacctgatggtgtagatggaatcaatgctaatgatgtggatatcaaa tgggtggagtaccagaacatgatcaaatacctcagccagtggatcaaacacaatgtggcc ataatgtcagatagatcattccccaacaaccctgtggaactcaaggcactttatacacag tatctgcagtttaaggaacatgaaatcccactgaaagagaacgagaagacgaaaatcgaa aatctctacaaaatgcttgagatgtggatcgagtttggacgtattcacttaccccagggg catcatcccaacgatgtggagaaggagtggggcaaattgattgttgccatgctggaaagg gagaagagcctgaggcctgaggtggaaaggcttgagatgttgcagcaaattgccaacagg gtccagcgggactgtgttaacggagaggacaagctggcgttggcatggacagccttacag tctgatgcaaaacgtctcgagtctggaattcagttcctacatgaggctgagattgcgggc tacttgttggagtgtgaaaatatcctcagacaacaagtggtggacatccaacttctactg gacgggagattcccctttgcagatcaactagtccaaagggtgtcaaaactgcgggacgac cttctaaccctgagagctgagtgttcttctgtgtacagccaaggccgaacgttgacaact gaacaaaccaagatgatgatctcgggcatcacacagagtctgaactccggcttctcgcag aacatgggcacaaacctgactccagccctcactcctgcactcacccccggggggatagct acccccgggtccccattcacctccagccttacgccgtgcctgaccccgtccttgaccccg ggcttgcagcctccttcagtccagtgctacatggggagtggcggcggcggcggcggcggc ggcggcatggacccaggaagcctcaggcatttgaaacacatgcagatccgcaagccctta ctgaaatcctcactggcagaccccaacatgacagaggaggaggtcaacatgaaatatgtt caggacctcctgatgtgggtggaagacatgcaggtgcagctggaccgttcagagtgggga tctgatttgccaagtgtggaaacacatttagacaaccacaaaagtgtacatagagccatt gaagaatttcaaatgagtcttaaagatgccacactgagtgaaattcaaatgaccattccc ctgaagctaagttactccgacaaattgaacaaactagaaaagcagtatgaacggctgttg agctgttcgagagagcggcagagccacctggagaacctactcgactttgtgtcgcaggcc actcaggagctcatctggctgaatgagaaggaggaggaggaggttgcctttgactggagc gatcgcaacagcaacatctccaagaaaagagactaccacgccgacctgatgagggagctg gatgaaaaggaggtcgtgatcaagtctgtgcaggacaaggcggaacgccttatgttcaag aaccacccagccaagacaactattgaagcgtacagagctgccatgcagacacagtggagc tggattttacagctctgctcatgcgtagagcggcatctcaaggagaacgctgtttatttt gagtatttccgtgacgccaaagagtccatagactaccttaagagcctgcaagacgccatt cagaggaaatacagctgtgatcgaacaagcagcctgcacagactggaggacctcattcag gagtccatggatgagaaagagcagctccttcagtaccgcagcgccgtcgccggtttagtg ggcagggccaaaaacattgtgcagctcagacccaggaaccctgaaagccccgtgaggtca tccatccccgtaaaagccatctgtgattatcgtcaaatagagattactatctataaagat gatgaatgtgtgttggcgagtaactctcaccgggccaagtggaaagtcatcaacccagca gggaacgaggccatggtgccctctgtttgtttcactgtgcctccacccaacaaagaggcc gttgataaggcgacaagaactgagcagttataccagaatgtcctggcactgtggcaccac tcccacatcaacatgaagagcgtggtgtcttggcattatctaatggctgacgtacgagcc attcgaaactggaatgtggcctcgataaagaccatgctgccaggtgagcatcagcaggtc ttgagcaacatgcagtcgcacttcgacgagttcctggaagacagcgaggagtctgaggtc ttcacagtggcagactgcgcccagctggagggagacgtcacggcctgcaaggaatactac caggaactgctcagatccgcagagcgagaggaacacgaggaatcggtgtacaacaattac atctcagaaatacgcaacttccgcatgcacctggaggcccatgaggaacacctgatccgg caaatccgcacgccgctggagagggacgacctggagcagagtctccagcgcatcacagag catgagaggaagacggcggagctgaataaagtgaaggaggacctcgatgtcatgaaggag aagtgcgagctgttcctcagacaggccgcaggttcttcgtctgtgccgacgctttcctct gaactcaccgtcctcgttcagagcatgagccaagtgtactccatgtcttccatttatatg gacaaactgaaaacagtgagcttagtggtgaagcacagccagagcgcagaggcgctagtc aaggcctacgaatccaaactctatgaggaagatgccatgaactccgaagtcaaatccatt gagactgtgatttcaacacttaagcaatggcggacggagattgacgagaaacaggaggtg ttccatgacatggaggatgagctgcagaaagcacgagctatcagcgaccgcatgtttaag gcccacaatgagcgcgactttgacctcgactggcacaaggaaaaagctgatcagctgagt gaaagatggcagaacattcactcccagattgactgcaggcttcgggacctcgatggtatc gacaaatccctgaaacactacagagactcatacagcattcttgatgaatgggttcgagaa atggaagtggcacagctgaaggcacaggaaaacaaacctgaagatagcaaggcactggct gagctgttaaacaaacagaaggtccttgttgctgaaattgaacaaaaacagagcagaatt gatgagtgtcagaagtattcggagcagtactcttctgccattaaggattatgaacttcag ctgatgaccttcagagcgatggtcgactcccaacacaaatctcctctcaagaaacggagg atgcagagctcttctgatgccattcagcaggagttcatggatctccgaacccgctacact gctctggtgactctcatgacgcagtatgtgaagtttgccagtgaaacgctgaagagaact gaagacgaggagagatctgttgatgaggagaagagagagcatggtgataaagttagcaaa ctattgcactggatgaaacaaagcctgaacaatgatgggaatgctatgaaagatagcaat gccaacacagatgcttctaataaaccccaggtgtcagtcgaggaaatggtcacaaagaag gaacaaattgcagaggcactgagggccacacagatgatgctgaacaaacacagtgacaaa atgacagaagaggaaagagagaaggcgcaggagcagctgatggcactcaatcaggcgtac agtgaactctcccaacagtgttcagatcagacgacctctgcagaagaggattttaaaccg agtgatcggatggatgggcttcggactgaaaccaagagtcccctgactgatcagatgact tggaacactctcccagaggcccaactcatgacctgtgatgctctcagacaagatcttgtg tacaaacccacgccgaaccacttgtcagagctgaacgatgcaaagaagtgcatacaaagt ccagatgtctcctctgtctccctctctgacatagcagcagctagggaagggccaacgttt gaagacctggtcatgaagatgatagaggtcaaacaagtctgcgatggagtggaggtgtgc tacacaggtgacacactaaccatagagagggcgtttcatagtggtttgatacctgcttgt gtctatgtaaatattcttcagagacagaagacctgtcaggaaatgataaatcacagtagt cctgaaaatgtgtcactcgtagagcctgagcacgagtttgaaccttgcaaggtcaatcaa ctgatattaaagtgcctcagcagaaataaaccactgacaccagggaggaatgttagtacc 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cagctgggggagttcaggtctgcagccaacgcgctcaccaagtggctggaggagacaaac gagaaagtacctgcagttcagccaagcagcagtgagaagagtctggagaaggacctgcag acagtcaccggattattagatgaatggacatccaagggccctgctgtccaagacctgaac agtgaaggatcggcactgtgcagcctcatcactttcctcacatctcctgccaaaacaaag actcccaacaagtcagctcttactaatggtggtggtggtggtccagcgagccattcctac ctaactaataaagagctgatggtgattcagcagaacgtgtcgttcgtcaacgagggatac gcgagcctcggagaaacgctgaagagtcgagccacggagctgagcagctcggtgcagtac gtgaaagaggcccaaaaggagacggcggacatgatgacgtggctgaaggacatgaagaag accgcggcatcatggaacaacgccgccacagagaaggagtcggtgaaaacacagcttgaa cagcagaaggcatttgaagacgacatgaagcagaagcaggagcggcaccagaagctcaga gagaagctcctcaacttgattaagactcatccgaactcccccgaggcagcgaaatggaag cagatgctggcagaaatagatgctgcatggacagatatcagtggctctgtggagcagagg aagcagcacctggagcagtccaacaagaatctggacatcttccaaaccactgagctgcag ctcggtcagtggctctcagagaaagaactgatgatgagtgtcctcggacccctttcgatc gacctgaacatgcttaaaatgcagaaacagcaagttcagatcctccagaatgaattcaag agccgcaaacctcaatatgagcaacttgaggaagctgcctcagccatcctaagctcctcg 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acggctgctgatagccttcttgaggtggccaacgtggacactcaagctgtgaaagaggag aaggctagcattggcaaaagagtggacaatgttgccgagggtctgcagagcaagagggag tccctggagatgatctcgcacacggttaaagaattcaacgatacctacaaagaggcaaag ggtcagctcgagagggctaagaagcaggtggatgcctataaatcccagggagtgcagggt cacagcaataagaacctgaccaacatgaaagcccaacataagagtttagagggcgtgcag aaccaaatagagcacctgaagagcatggccaaggaccttgtagtcaacgtcccagatgcg gatggtgtgacagacctcttactgcacactgacagcatagaaaatgactacagctccctg aacaagatactggaggagacgtgccaagtgttggagggtaaactgcagggtattgggcaa ttccaaatcagcatccgtgagatgtacacccatttcacagacctggatgacgagctggac agcatggctcctgtggatcttgacttggccacacttagcgaacagcggggcagcatccag agctttgtggctaagttgcaggacctgatggccaacacagccaatgctggagacagctgt aagaagatgctggagaccgaaacctcgcccgacctgttgggcctgaagagagatctggat gccctgagtaagcagtgtggcaagctgtcggacagagccaaaggcagagaggtgcaggtg cagagtaccttcgccaagctggaggagctgtacggcaagctccaccgaatggaagatgag ctttgcagagctgtggacaaggaggcgacccagggagcggtcggcatggagacagacgtc attaaccaacagctggaggcctttaaggctttccagaaagaggacattgatccattgcag acgcagctccaagacatcaactccctcggccagggtctgatccaaaatgctgccaaaggc accagcaccaagaagcttgatgatgacctggagggtgtcaacacgaagtggaataccctc aataaaaagattgctgaacgttcagcccagctgcacgaagccctgttgcattgtgggagg ttccaggatgccctggagtccctgctcagctggttgactgacacagaggagctcgtggcc aatcagaaacctccctctgccgagttcaaagtggtcaaggctcaaatacaagagcagaaa ctcttacagagactgctggacgaccgaaagccgacagtggagctaataaaaaaagaggga gggaaggtcgcggaactggcggagtctgtggataaggagaaagttgcaaaggagatcgaa tgccttgggcagaggtgggacgccctgctcaagaaggctgaaaacaggcacaagcaacta gagagcatattggtggtcactcagcagttccatgagactctggagcccctgagcgagtgg ctcgccgccacagagaaacatctggccaactctgagccaaccggcactgagacatcgaag ctgcaagatcagatctgtcagcataaggccttagaggaggagattatgaatcacagtaaa gacctgtttcaggccgtcagtctgggtcaggtgctcagaactgtgagctcagtggacgat aaggagtttgttcagtctaagctggacgccgcgcaggccagttacatagagctccaggag cggtgcaggaggaaagccgagatgctgcagcaggctctggcaaacgcccggctgtttgga gaggatgaagtggccctcatgaactggctcagcgaggtgcacgtgaggctgggcgaagtg tccgtggaggactacaaaatagatgttctcgaaaagcagctggcagaacaacgggggcta caaagtgatattgagttaaggaagaggaatgttgaccaagccatatctaatgggatggag ctactgaagcaaacaacaggtgacgaggtggttgttatccaaggcaaactggacggtata aaagccaaatatgctgagatcaactcgatgagtgacaatgttctgaagacactggagcgt gttttgagtttctcctctaagctgcaccataatcatgaggacctgagctcgtggctcgag aaagtagaggctgagatcagagcttttgccgaccaggagccagtgggtgatcagctcatt catgcacaaagcaggcaaaaggccttgctgaaggagaccaaagaccaaaagcctgtgatg gacaagctgaacgagttgagcagttccctcctggatctgatcccctggcacactcgcgag ggtctggacaagctggtaactgacgacaatgagcggtacagagccgtctgtgacacgatc acccagcaggtcgaccagatcaacgctgacattctcaagtcacagcagtttgaacaggct gcagatactgagctctcctggctgactgaagctgagaggaagctgctgtcgatgggcgag atccggctggagcaagaccaaaacgcagctcagctccaagcacaaaagattttctccatg gacgtcatgaggcacaaagatgccgttgatgagattgtaaaaaacggaaaggcaattatg aacagcaaaaacccagaggagaaagaaaagttgaaggccaagacccagaccctcttggag aagtacggtaccgtcagtcagctgaactcggagcgctgtctgcagctggaacgaacccag tctctggccagtcagttctgggagacctatgaggagatgtggccatggctccaggaaacc ctgagcaccttcagccagctacccccgccttccatcgagtacgacagactcaggcagcag caagaggagctcaggcaaatgagagagctaattgcagagcacaagccacacatagacaag atgaataagaccgggcctcagttacttgaactcagcccagtggagggagtgcccatcaga gagaagtacacagctactgaccagctctacatccaactgaaggcggatgtcaagcagaga gctgccactctcgacgaggccatctccaaatccacccagttccacgataaaattgacccc atgctggaatcactggaacggattgccgagcgcttgcgtcagccgccatccatctcggtg gaggtggacaagattagggagcagatcaccgaaaacaaggccgtctatgtggatttggag aagctgcagccgtcttatgaaacgctgcgacagcgaggcgaggagatgatcgcgcggtct gagggggcagacaaggacatatatgctaaagctgtacaagaccaactggaccagatggtg ttcctgtggagcgacatccaggccttgctggtggagcgcgaggcgaagctgctggatgtg atggacctggccgacaagttctggtgcgaccactgcgccctcatcgtcaccatcaaggac agccaggacctgctgagggagctggaggagcccggagtcgacccgtcagtcgtcaaacag cagcaggagtttgtggagggatttaaggaggagattgacgggctgcaggaagagctggat gtggttcaaaaccagggggcagaactcatgactgcctgtggggagcctgataaacctgtg ataaagaagagtattgatgaggtgaattcagcgtgggagaatctcaacaagacctggaaa gagagaggagagagactggaagaagccatgcaggctgctgtgcagtttcaagacggcctg caggggatgtttgactgggtggatattatggagagcaaactggattcaatgtcacctgta ggcacagacctggaaactgtcaagcagcagattgtggaactcaaggagttcaaaggagag tcgtaccagctgcagatcgagatggagcggctgaaccaccaggcaggcctcctgctgaag aaggtgacggaggaggccgatcgctgtgagatccaggagccaatgtctgagctcaggatg ctctgggagaacctggatgagaagatcatcagccgacagcacaaactggagggaggcctt ctggccctgggccagttccagcatgcgctggacgagctgctggcctggatgagccacacc gaggagctgctcgacgagcagaggaaggccggaggagaccccaaagccatcgagatagag cttgccaaacaccacgttctccaggttgacgtgttggctcacaaagccacagttgagacg gtgaacaaagccggtactgatctggtggagtccagcgctggagaggaagccgctggtctg cagactaaactggagaacctgaaccagcggtggaaagccatccaggagaagacgaagcag aggaagcaacagctggagagttctctgcttcaggcccaaggtttccatggtgagatagaa gatatgcagcaatggctgaaagacacagaacgtcagctgttggcatcaaaggctgtggga ggcttaccagacacggcccgggagcagcttaacgcccatctggagttgtgttccgccttg gaggcgaaggaggagctgtgtcaggagctgttgaacaagggtcaccagctgctcgccatg acgcccgagggtcctgacagcaacaccgagcaggacctcgccaacctgagggagaaatgg gaagcggtgcagggcaaggtcgctgaaagaaaggcgaaactggaagaggccctgacactg gccacggacttccacaactctctgcaggacttcatcaactggctgacccaggcagagcag acgctcaacatggtttcccccgcgtcgctcatcctggagaccatcatgtttcagattgac gagcataaggtgtttgtgacggaggtgaactcccacagagaacacatcattgaactggac aagactggaacccatctgaagtacttcagccagaaacaggatgtggtcctgatcaagaac ctgctgctcagcgtgcaaggccgctgggagaaggtggtgcagaggtcggtggagcgaggt cggctgctggatgactccaggaagcgggccaagcagttccatgaaacctggaacaaattg atggagtggttggacgaatctgagaagactctggactccgaggtggaaattgccaatgat ccagacaaaatcaagacgcagctggcacagcacaaggagttccagaaagctctagggagc aaacactcagtgtacgacactaccgctcggacagggcgggccctgaaagacaagacctct cttcaggacgataaccagaagctggacgacatgctgagtgaactgagggacaaatgggac actgtctgcggcaagtcggtcgaaagacaaaacaagctggaggaggccctgttgttctcc ggccagttcacagatgctctccaggctcttatcgactggctgtacagagtggaacctcag ctggctgaggaccagcccgtacacggagacatagacctggttctcaacctgatagacaac cacaaggcttttcagaaagagttgggaaagaggacagtgaccgtccaggccctcaaacgt tcagccagggagctggtcgacagcagtcacgccgactcgtcctgggtcaaggtccagatg caggagctgagcacccgctgggagacggtgtgcaacctctcggtgtccaaacaggcccgg ctggagcaggccctgtgtcaggctgaggagttccactctacggttcatatcctgctggag tggctggctgaggcggagcagagtttgcgtttccatggcagcctgcctgatgacgaggag gctttacgggcgcttatagaacaacacaaggagtttatgaagaaactggaggaaaagcga gtggctctgaacaaagcaaccagtatgggcgaggccatcctgagcatctgccacccagac tctatcacaaccatcaaacactggaacaccatcattaaagcccggtttgacgaggtgcag gcttgggcccggcagcaccagcagcgactggccacggccctcactgagatgctagccact caggatctgctggagaatctgctgacctggctgcagtgggccgagaccaacctcaacgac aaggacaatgagccgctgccgcaggagctggaggaggtcaaaggcctcattgcggaacat caggcattcatggaggaaatgaccaggaagcaaccagatgttgacacgatcaccaagaca cacaaaaggaaggctgcggtggagccccaaatccagtctcacatccctgtgcttgaaaaa ggaagaactggaagaaaacgttctcccacgcaaacaatgtatgcgtcagcaacacaagct cccattgaaaccaagaacccccgggtcaaccttctggtcactaagtggcagcacgtttgg cttctggctctggacagaaggaggaaactcaacgacggcctggacagactggaggagctg aaggaatttgccaacttcgactttgatgtgtggcggaagcgctacatgcgctggatgaac cataaaaagtctcgcgtcatggacttcttccgccgcatcgacaaagatcaagacggcaaa gtgacccgccaggagttcatagagggcattctctcctccaaattccccaccagtcgtctg gagatgagcgctgtggcagacatttttgacagagacggtgacggttacatcgactactac gagtttgtggcggctctccatcccaacaaagacgcttacaaaccactcacagatgcagac aaaattgaagatgaggttacacgtcaagtggcaaaatgcaaatgtccgaagcgattccaa gtggagcaaatcggtgccaacaaataccggttctaccttggaaaccagtttggtctggtt cactgcttacatgactccttaatcggcgatgagacaatagcaatcagggaaaatcaaaat cttaccccccacctgaacgtggcagttttggaaagctgtattctgttcggagactcccag caactccgcctggtgcgcattctacgcagcaccgtgatggtgcgggtgggaggaggctgg atggctctggatgagttcctggtgaagaacgacccctgtcgagttcaccaccacgggagc aaaatgttgcgctcggaatcaaactcttcgattactcagtctccgataggttggcatatc tcacacttactctccttgctccatgaacccgagagcgctaaaggcaggaccaacctggag ctgcgagagaagttcatcctcccagagggcaccacgcaggtgatggccagcttccgctac cgaggccggagatcccggccgtcgtccagaggagcgtcccccaacagatccacctccagt cagagctgtccggtcccaccaaacccggtattgaccagtacacccaagactccccaacac ataacccgcaattatgataagccctggcttacaaacagcaaaccctccactcctcttaaa tcatccgactcctttgagagccaaggttcatcctcagagatgacaccagtccacggcagc aagttacgtcttcctgggtacttgtcaggtaaagggtttcagtctggtgaggagggaacc ctgatcagcgctgcagtgctgaaagcccgaacacagacaataggtgagtcgagaagaaac tccagcagaccaggaagtaaagccgggagcagggggagcagccggcggggtagcgacgcc tcggacttcgacatctcagacatccagtccgtgtgctccgatgcgtcggagaccgttggc gagtcggccagggcgacgccgcgttctgcttcgcgccagcgcggagggaaaccctccaag atccccactcctcaaagaagaaccactcccacgagcaaactggccaagggatccaagcga tag

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