Scophthalmus maximus (turbot): 118289453
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Entry
118289453 CDS
T09850
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
smau
Scophthalmus maximus (turbot)
Pathway
smau04217
Necroptosis
smau04620
Toll-like receptor signaling pathway
smau04621
NOD-like receptor signaling pathway
smau05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
smau00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
118289453 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
118289453 (tyk2)
04621 NOD-like receptor signaling pathway
118289453 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
118289453 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
smau01001
]
118289453 (tyk2)
Enzymes [BR:
smau01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118289453 (tyk2)
Protein kinases [BR:
smau01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118289453 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
Kinase-like
FERM_C_FAK1
ABC1
Carm_PH
SH2
Motif
Other DBs
NCBI-GeneID:
118289453
NCBI-ProteinID:
XP_035472378
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All DBs
Position
17:14250025..14259069
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AA seq
1157 aa
AA seq
DB search
MSRKWWSKRSKPGACHDDPTQGQGVHVFLLWTREGERYLSHTGGEVTSEELCILAAEAVG
IAPLCHVLFALYNPLLRCWYSPNHVFSADENSGLVLHYCMRFYFHNWHGLNEKEPTVSRY
RLRSGTDQGSSPLLDMTSLEYLFAQAKYEFVNEVVQMEDIQSEDELSRFKNESLGMAVLH
LSHQAIQTGCTLQEMAEKVSFIHCIPKSFSKHISKDNFLTKIRINRVFADFVRTFQQHTV
DKERLGGQEIMYKYISTLEHLAPQFGTETFPVSQLEVREDGNGSSSYSDSTNAQGVSKDN
FVAPATHEIVVSGTKGIQWRTVSIQKAQANAYLRSYYMNTTKSKHQSSQATAKTPNKLSS
FCDFHEITHIALSGANVCISTQDNQCMVVQMNSSQEARSFISLLDGYYRLTADAHHYLCH
DVAPPRVVLSEANGLHGPMHDDFVLLKLKKEAAEEGAFLVRWSGLDYRRIILAVLNKNKN
GSTPSHKQFRIQHNGSTFCLEGLERDFSSVKELTDSLKSFVLKSGSDSFTVKKCCLPRQA
ELSNLLVVRQGVDHRDNFSSMTQLRFHQIKDKELVQKQHLGRGTRTNIYSGRLLVRGQGD
NNHEDEFNNNSNDSSVIRVVLKILDQSHEDIALAFFETASLMSQVSHSHLVFVHGVSVKG
SENIMVEEFVEFGPLDVFLRKEKASVTPQWKFIVAKQLASALSYLETKRLVHGNVCAKNI
LVARRGLEHGTTPFIKLSDPGISLSILSREERLERIPWIAPECVDSGAPIGNAADQWSFG
VTLLEICNNGDLPMSGFSLSKKELFYQQKGRLAEPSSQDLASFISMCLTYEPVERPSFRT
LLRKLTEIMIKNPDISPSETLPDADPSVFHKRYLKEIRDLGEGHFGKVTLYLYDPANDGT
GECVAVKALKQENGHAPDGWMKEIEILKSLYHSNIVKYKGCCTELGGQVVQLIMEYLPLG
SLREYLPTHKLGVPQCLMFAQQICQGMEYLQSKRYIHRDLAARNVLVENEGLVKIADFGL
TKYIPEGEIYYRVREGGDSPVFWYAIECLKENKFSFSSDIWSFGVTLYEILTRCDPRQSP
PIKFMEMMEATRGEMTMMVLLKLLERQLRLPCPKECPHEVKLLMEQCWAAKPAQRPSFKS
LIESLEAIRRTYDWESI
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atgtccagaaagtggtggtccaagcgttcaaagccaggggcatgtcacgatgaccctacc
cagggtcaaggcgtccacgttttcctcctctggactagagaaggggagagatacttatcc
cacacgggaggcgaggtcacgtcagaggagctgtgcatcttggcagcggaggctgtgggg
attgcacctctgtgccatgtgttgttcgccctgtacaatccactattacgctgctggtac
agtccaaaccatgttttcagtgcagatgagaactcgggcctcgtacttcactactgtatg
agattttactttcacaattggcacggactaaatgagaaggagccgactgtatctcgctat
cgtctccgatccgggacagatcaggggagttcccctctgcttgatatgacctccttggag
tatttattcgctcaggctaaatatgaatttgtgaatgaagtggtgcagatggaagacatt
cagtcagaggatgagctaagtcgcttcaaaaatgagagcttggggatggccgtgcttcac
ctctcacaccaggcgatacaaacaggctgcactttacaagagatggcggagaaagtcagc
ttcatacactgcattccaaagtctttctccaaacacatttccaaagacaacttcctgact
aaaatccggatcaaccgggtgttcgcagactttgtgcggaccttccagcaacacactgtg
gataaagagcggctgggaggccaggagatcatgtataagtacatctccactcttgaacac
ttggcgccgcaatttggcacagagaccttccctgtgtcccagctggaggtgagggaggac
ggaaatggaagtagctcttactccgacagcacgaacgcgcagggcgtctccaaagacaac
ttcgtggctcctgccacacacgaaatagtggtgtctggcaccaaagggattcagtggagg
acggtgtccattcagaaggcgcaggcgaacgcttacctcaggagttactacatgaacacg
acgaaatcaaaacaccagtccagccaggcgactgctaaaactcccaacaagctgagctcc
ttctgtgatttccatgaaataactcacatcgccctcagcggagctaatgtgtgcattagc
actcaggacaatcagtgcatggtggttcagatgaactccagccaggaggcccgttccttc
atctcgctcctggatggatactaccggctgactgcagacgcccaccactatctttgtcat
gatgtggctcccccgagggtagtgctgagtgaagcaaatggactgcatgggcctatgcat
gacgattttgtgctgctgaagctgaaaaaggaggcggcagaggagggcgctttcctcgtc
cgttggagtggtcttgactatcgccgtatcatcctggctgtgctcaacaaaaataagaac
ggatcgacgccgagccacaagcagtttcggattcagcacaacggttcgacgttctgtctg
gagggcttggaacgagatttctctagcgtgaaggagctcacagacagcctcaaatccttc
gtactcaagtctggatcagacagcttcactgtgaaaaaatgctgtttgccacgacaagca
gaactatctaaccttctggtggtgaggcaaggtgtcgatcaccgagataactttagctcc
atgacccaactacgtttccaccagatcaaggacaaggagctcgtacagaaacaacatctg
ggccgcgggaccagaaccaacatctactcgggccgtcttctcgtgcggggacaaggagac
aataatcatgaggacgagttcaacaacaactccaatgacagcagcgtgatccgagtggtt
ctcaagattctagaccaaagccatgaggacattgcactagccttttttgaaacagcaagc
ctcatgagccaggtatcccacagccaccttgtgtttgtgcatggtgtgtctgtcaaagga
tctgaaaacatcatggtggaggaatttgttgagtttgggcccttggatgttttcctccgc
aaagaaaaggcgtcggtgactcctcagtggaaattcatcgttgcaaaacaacttgcaagt
gctctcagctatcttgagaccaaacggctggtccatggaaacgtctgtgccaagaacatt
ctggtggcaagacgaggcctggagcatggtactacacctttcatcaagctgagcgatcca
ggaatttccctgagtatcctttcacgggaagagcgtctggagcgcatcccgtggatcgcc
cccgagtgtgttgatagcggtgcacccatcggcaatgctgctgaccagtggagctttggt
gtcactctgctcgaaatctgcaacaacggcgatcttcccatgagtggcttttcattgtcg
aagaaagagctcttttatcagcagaagggtcgcttggctgagccatcctcccaggacctg
gccagcttcatcagcatgtgtttgacctacgagcctgtggagaggccttcgttccggact
ttgctccgaaagctcacggaaatcatgatcaaaaatcctgatatctctcccagtgaaact
ctccctgacgcggaccccagcgtgttccataaacgatatctgaaagagattcgggacttg
ggagagggtcactttggaaaggtgactctctacctgtacgacccagccaacgatggcact
ggggagtgcgtggctgtgaaggctctgaaacaagagaatggtcatgcgcctgatggctgg
atgaaagagattgagattctgaagtctctctatcacagcaacattgtcaagtacaagggc
tgttgcaccgaactgggaggacaagtggtgcagctaataatggagtaccttcctctgggg
agtctgcgagaataccttcccacacacaaactgggtgtgccccaatgcctcatgtttgct
cagcagatctgtcaggggatggagtacttgcaatcaaagcgatacatccatcgagaccta
gccgcccgcaacgttttggtagaaaatgagggtttggtgaagattgcagactttggcctg
acaaaatacatccctgaaggcgaaatatactatcgtgtccgtgagggtggggacagtcca
gtgttttggtatgccattgagtgcctgaaggagaataaattttccttttcgtctgacatt
tggtcctttggcgtcacgctgtatgagatccttacccgctgtgacccacggcaaagccct
ccaataaagttcatggaaatgatggaggcaacccgaggagagatgactatgatggtcctc
ctaaaactgctggagagacagctgcgattgccttgtcccaaagaatgtccacatgaggtg
aaattgttaatggaacagtgttgggctgcaaaacctgcacaaaggccttcattcaaatcc
ctcattgaaagtttggaggccattcgcagaacatacgactgggagtcgatataa
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