Scophthalmus maximus (turbot): 118311968 Help Entry 118311968         CDS       T09850                                  Symbol pkd1a Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism smau  Scophthalmus maximus (turbot) Brite KEGG Orthology (KO) [BR:smau00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:smau03037]     118311968 (pkd1a)    04812 Cytoskeleton proteins [BR:smau04812]     118311968 (pkd1a)    04040 Ion channels [BR:smau04040]     118311968 (pkd1a)    04091 Lectins [BR:smau04091]     118311968 (pkd1a) Cilium and associated proteins [BR:smau03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    118311968 (pkd1a) Cytoskeleton proteins [BR:smau04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     118311968 (pkd1a) Ion channels [BR:smau04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    118311968 (pkd1a) Lectins [BR:smau04091]  C-Type lectins   Others    118311968 (pkd1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PLAT PKD_channel Polycystin_dom LRR_8 LRR_4 Lectin_C WSC GPS LRR_LRWD1 LRR_5 Motif Other DBs NCBI-GeneID:  118311968 NCBI-ProteinID:  XP_035492045 LinkDB All DBs Position 8:17436268..17490495 Genome browser AA seq 4655 aa AA seqDB search MPCGNGQTLSKRKHGVCAPRLRFFSSLLVALCCLEAWGSGPRADGGRGCGGSCPANCSCA LAGHQPSCVVNCSNTGLERAPAAADVPPATSVLDLSKNHISSLDTSLLDRLTGLRELYLQ GNRINVLPRGIFCCGPLSVVDLSNNQITTIEERICDNLCNLTQIDLSSNPFDCDCKLFRL VSWLQEKGVRVRRPDAMLCNHPPELRHQPLLNVSLLTCGLNYAACLEDSSSVGGGRSELV IFSSSTPGNFTREQCNSVCFAASHRYGGLGARHECLCSTNSEPNFISESQCSAACTKPHV MKECGWTLAHDVFAVDFSISLKSLPLQSVHDPVTLAATSSVSPVTLSWDFGDLSSRVNAT GAGLTTAAHKYGLPGHYAVSVLAWAGHKEVSARGEVTVTVPPKLELRCPTLAVANKSLEF TLVSWGAVGVDVDWKITKDGVQVAKAFPPCPKDGMYHGESSRCFQIVPGELSWTDARKQC SDRGGDLAIVRTDALRNLLAPKVTQERGVWLGLSDVNSPGKLPRSPIARGNVCVSLDQRG QTSSHPCNAKRAYVCQYRPQVRVPDAGIYLAGLPVFASHNPLHRAPSSPLSAPQPPSSGI EVLLFPALSFVQGGRLSSLEFVTQELSSQTHVRFQTYRPHCHYPDLHLLLPSCGGPACAP VAVCVPNDTRTSDPTSCPRLKQWCPFMHRCLALSSPCQPSSCPNCTQTHRLPPGALRPRY TLQNEVVFTLPAGPAAHVVVQEGLEDLLVSRGDVIALQHDAGPASLLRCQSSPHSLWRQP VLALNQSEWFWLNNTGQSTDRATDADPLPDPELDVEVLVEDGEGGWLEDVVCPVRVLYVG HSETQLQGGQLSAGLPQPGLYSLLVTSAEPSYPASASCPLRVVPPLGLTILHPLPQNGTI YLQPNDTRLLLRVQSRYVTQAYQRDGNRSVTFQPECPSEFSSGPSLCLPGPSSGTGSKVT EPSLYAVLDLNLGVEEKTGPMQVDLEAHNNVTEASLIVVVHLEEPLRGLVVQPHPAHRVL MESVVSYTASVREGSSPTFKWTVDDKPYFTYYNTVLNVIYQHAAVYKLTVTAMNHVSALT EHFNVTVDRLQPMADLTVRGVPDVVPQGSTQTLTTSVLIDTSVAATFRWSFGDGGYKEFE YKPPYDPTLLCPDSPNQVLLSNNVTYIYSQPGIYTALVSVSNRYDNISQSINMSVYSILT RVDIQTEPRLLLAGKSADFEAHPLPSPYGIHYDWHFGDGSTPLQGRRVAHTYAQSGTVNV CVSVNNTISSMEACAEMFVHERIEDLRAESSSPTELHSPTTVRAHLASGNNITWTFSMGD GTIYSTSEPHVTHSYIEDGNYTVNVTAANAVSFVWTILPVQVFVFQVIRMEPFGCVQEQT PVNFQAWVSGNESAHLYEWCFGDGSSNETHHGNPRVSHTYLTSGNYHLSLLLSSRVNSAT KANFFNWVCVQPALTNISLTLVKLHYAVGEEILFQVKAEPEFNYSYQWDFGREEDLVPGH GSGNILTMYKNPGHYMVTVIVFNNISCSNTSVVIEVLMPVGPIVIQHNGTKYNNLTLKAA YAFTTSSLASNVSYTWNFGDGNLFTGQNTHHTYNISGIYNVTLTAANTVSRNHTTLPVAV LAPIRGLTVNASLVNVPLNASVHFEAQMEEGDGVRFSWILCDRCTSIPGTHTMFYTFRSV GTFNIIVTAENDVGTAQASIFLFVQRELEGLQILAEEEICGGTRVDGCCFATNRVLHLQA GLKEGTNMTFTWNLLRELDPVGSSFNVSGKTVEVNFSTPGPCEIFLRAANLLGQLSVNRT IHFLEPARGVFLQISNNPVAVDSPTNLTVLTMEGSDLQYHWSVNGDTLPWNKPWKTHTFI SPGQKLVTVKVFNEVSSEVVSQNVSVQEIISGLRFTATNVEEQSYVATGVSVTLQGEVLT GTDVTWTWLLDGRTDTGRRTSLIFQEPKTAIVTLNATNDVSGQVVSREFFAQDKIQGLEL RASTKIAAVGEKVEFTISMAGGSDVCLILSISGDATVITQPNHTYVHVFSRVDTYMVNLT AHNKVSSKRRQLQVEVMEPVRELSILGSSAAIPVGVKRLFVANILTGKPVHFLWTFDLHH LHRKSHIGKEVSYTPEEAGLLTIYVKVFNALHAQNITKHILVQNLLTAAILYAAPQDTFI NKMITLMASITPRSNSVECLWDFGDGSTPVHTNKTSVGYEYRHPGHYLVQVNCSNLVSWV LAQVEVDISVLECEEPEVQVLQAPRLAIWRSQPTLVEAGVDLKGCIRYGAQYLWQILSTP SCDSDKDDRITSGAVSQPSRSLLVPVMRLPVEVDVRRLQLSLPKMALATGNYSLVFSLSY EGVPLRKAACLQLSVMAARLMPIIEGGTYRVWSRTQDLQLSAEQSYDPNLDPHSQSLLHY HWDCQSTSKGPEHCSSLNFGLGSSGPVLGISGSELEAGVEYTFKLTISKEGMPPESTTQT VFVQSGHIPMVYLECVSCKAQSIYEVSQNSYVYLRGTCTNCQGFHRGRWSAMTLKNEALV LDSSSTTTGSDGMNLVLRQGVLRHIDSYIFTLHVTDSSLDGEGVASITLHHNTAPAGGEC HLRGGGQAGVEYGDGDGEAWRLRTLLDRVHFNCSGYSDRGVSESPLLYSLLVTRCREDYC EDFCVYKGSSPEHSAFLPPGFRSARHRVAVSITVEDHQGAAITALDKTVEVVLPDPPSGY SSLPHWLSQLTDSKLKKLLEQGDSQRVRELSLALITVLNEYEQTRESARVSREERGYRVR VRSNITRALTALDLTTVNDIQQTSAALAQCTAVSREFICEECQNSTLNKLESMLEILQTD TKQGTVTPTEIADNILNIMGDLIHQVSQSASQSYFQSAYVDSPSPANNSFSSSGEEHGGA LLDPSPSSLEPHPLRVAAKAYSLSSVLMLILMHARVLNEEPLVLRGAEIAATGKLADPQS LLCYHGNNSPECQRFSIPRAFNHSLGRAAAGNSIMQLLFQVESNPFPFNYVANYTVSTEV ASMEFRTENGTQIPISGLDDNLAITVAINNGSNGEVGVEGSGGGGLPTAGAINISHCDSV VVRVSTGNTNRQAGLFVQLNFTSLEDAREKDNRVEDEVEPHITAYLNSHEGPSEFNCTDR KRITLSMTRGQDLDHKKYTFFLSPELYDTTLDYFINVSTPCSPGSRPVGVRLEVGVFASL CQYFSESEKQWRTDGMVPLAETNASRAVCRTRHLTSFAAGLFVPTNAISFIAPERSGPPS LVVLLVCVLGLLSYVVAAAILHKLDQLDLRRAGVVPLCGQDGLFKYEVQVKTGWSRGAGT TAHVGINLFGHESRSGHRHLDSRGAFSRNALDIFHIATDSSLGSVWKLRIWHDNKGLSPA WMLQYVLVKDLQTGSSYFFLVEEWLSVDNERTDGRVEIEVEASEEAVLRQVPRLAWCELQ RALCESHLWLSLWERPPRSPFTRLQRATCCTVLLQLFLLANTLWYSIVVDKRHSPRAVSR LSTLNGETVAAGVVTCLIVYPLYLLVFTLFRMSRSKCVSVEQVPPQVDQESVEIDDFLEN SMAGSSFLFYNGETNSEETNVDLPTPSTKSVDSWTMAEEETEDRDWPELLSDVSVVGGAG HGAGLPRLKRGQGSRHLGVDMTFNPDEDEGTDQRNKYFTSSDEDLIKHILTDGQNFFPQA DESEMADLSSIFGDKTEVILLQKLNEPLPLESVRRDPPKTAFTSKTVVTDVCRPRRFPPW CGRATLWGSWAGIALANAVSIWAAHGFSQNVAMMWLISCFASFLCSCLLLEPIKVLCEAV YYAVFVRRLRPEDQDVLVEFPRVERVVQRVPRVRPPQGFALSQARHQARKVHMLHTMLKN FLVYMFFLLVVLLLNYSDSAKDTHSLRLRNQLQQALHTPEYHNIHSRDEVFMWLNESLLP RLLEDSALLRDTGTVLLGTLRLRQVRDTQVAGGAWAGDSVWSKGWFTPLNKDAENFTDFG ASHANGVWRLGQVRVHNSGDVVQQLNRSLEEASSSLQQLRQLHWLDFRTRAVFVEFSLYN INTNLLAVFSFLFEFPVSERALSSLDLHVITLWPIISLDLQLLLTIILLILVLYFLVRGI LGFLREGYRYLLSAWRLLGVCKLTLAAFVCGLHLSRCTMAKNQWTLYMKHPRDAFTDFYP LARQSQMYTVMSAWLLFILVLKASHQLRFLREWAVFGRALRRSVWELLGVALALLLLMLA YSHTGHLLFHSVLDGYDSVSSAGLSLLGAGGRGLLSWRPGWTITGPSNTVSSLVFHASFA VFRLVLLWLITSVLLRNYRRARAELYRPAVDLQDYEMVELFLRRLKMWMGLSRAKEFRHK VRFEGMELPPSRSSSTSDCKSLCLPPLDGPDSPPTPDSVDAGSEASWRPASSSPCSLTEA PGIGLGLGLGLGLGLGPRVVVGGTSWRERAETEASLRRLLPTLDALLQQLDRVTMATEDL YHIECRLERAQRKRRRRGRERGGGGGQRGKGDDKDSAGWRERKSGKEKHKGSKKGKKDCG NTAANPKKTPVATPVPFLKPRPTLASTHTPAPQSSAKPSVSAPPPTPVSDKSASDSSSLP VSTANTPPTHVPMPKTPTAPPCTPAPCLPSTPASTPITRDWDPPREKETLPASSLFNHPA HTTTIPTRKRKRKPPPLKNKVHPNLDRHGSGHPKS NT seq 13968 nt NT seq  +upstreamnt  +downstreamnt atgccttgtggaaatggacagactctatccaagcgaaaacatggcgtctgcgcaccgcgg ctccgcttcttctccagcctgctcgtggcgctctgctgcctggaggcgtggggctccggg ccgcgggccgacggcggccggggctgcggcggctcctgtcccgcaaactgcagctgcgcg ctggcgggccaccagccgtcctgcgtcgtcaactgctccaacacggggctggagagggcc ccagcggcggcggacgtcccgccggccaccagcgtgctagatctttccaagaaccacatc tcctccctcgacaccagcctgctagatcgtctcaccggcctccgagagctgtatcttcaa gggaataggatcaatgttctccccagagggatattctgctgcgggccactgtcagtcgtc gacttgagcaacaaccaaatcaccaccatcgaagagagaatatgcgacaacctatgcaat ttaactcaaattgacctgagcagcaaccccttcgactgtgactgcaagctgttccggctg gtcagctggctccaggagaaaggggtgcgagttcggcgtccggacgccatgctctgcaac cacccccctgaactccgccaccaacctttgctcaatgtcagcctgctcacctgtggtctc aactatgcagcctgtctcgaggatagcagcagtgtgggagggggccggagtgagcttgtc atcttctcttcatccacacctggaaacttcacacgggaacagtgcaacagcgtgtgtttt gcggcatctcaccgctacgggggcttgggggcaaggcacgagtgtctctgcagcacaaac tctgagcccaacttcatcagtgaatctcagtgttcggccgcctgtacaaagccccatgtc atgaaggaatgtggatggactcttgctcatgatgtgttcgcggtggacttctcgatatcg ctgaagtcgctgccgctgcaaagtgttcacgaccccgtcacgttggccgccacctcctct gtcagtccggtgacgctgtcctgggactttggtgacctttcatctcgggtcaacgcaaca ggagcaggcctgaccacggcagctcacaaatatggacttccgggacattatgcagtcagc gtgttggcctgggctggacacaaggaggtctctgcgcgtggagaagtgacagtgacggtt cctcccaaactggagctgcgttgtccaactcttgctgtggccaataagagcctggagttc acgcttgtcagctggggagctgttggcgtggatgtagactggaagatcacaaaggatggt gtccaagttgccaaagccttcccaccctgtccaaaagatgggatgtaccacggcgagtcc tcgcgctgtttccagatagttccgggggagttgagctggaccgatgctcgaaaacagtgt tccgaccgcggcggggatctggcaatagtcaggaccgatgcactgcgtaacctgctggca cccaaagtcacacaggaacgaggtgtgtggctgggcttgagtgacgttaactctccagga aagctgccccgctccccgatcgcccgtggaaacgtgtgcgtgtccctcgatcaacgtggt cagaccagttcacatccatgcaatgccaaacgtgcctacgtctgccagtacaggcctcaa gtgcgtgttccagatgcagggatctacctagcggggctgcctgtgtttgcctcccataat cctttgcatcgtgccccctcctctccgctctctgctccacaaccacccagcagtggcata gaggtgctgctgtttccagctcttagcttcgttcagggaggtcgtctatcctcacttgag tttgtcactcaggaactgagctcacaaacccacgttcgattccagacctacaggcctcac tgtcactacccagacctgcacctgctgctacccagttgtggaggtccagcgtgtgctcca gtggctgtttgtgtcccaaatgacactcggactagtgatccaacctcttgcccccgactg aagcagtggtgtcccttcatgcaccgctgcctggctctgtccagtccctgccagccatcc tcctgtcccaactgcacccagacacaccgcctgcctcctggggcgctgaggccacgttac accctgcaaaatgaggtggtcttcactctaccggcaggaccagctgcacatgtcgtggta caagaaggcctggaggacctcctggtttcccgcggtgatgttatcgccctgcagcacgac gctggccccgcgtccttactgcgctgccagtcctccccacactcactgtggcgacaacct gttttagccctcaaccagtcagagtggttctggctcaacaacaccggacagtcaacagac agagcgactgacgccgaccctctgcctgacccggagctcgacgtggaggtgctggtagag gatggcgagggaggatggctggaggacgtggtctgccccgtcagagtgctctatgtggga cacagtgagacccagctgcagggaggacagttgtctgctggtttacctcagcccggactc tacagcctgctggtgacctctgctgagccgtcatacccagcctcggcatcatgcccgttg cgggtggtgccccctctgggcttgacgatccttcacccccttccccagaatggcaccatc tacctgcagcccaacgacacccgcctgctgctccgtgtccagtctcgctatgtaacacag gcatatcagcgagacggtaatcgcagcgtcaccttccagccagaatgtccatctgagttc tcgtccggcccgtcgctctgtctgcccgggccgagctcggggaccgggtccaaggtcact gagcccagcttgtacgcagtactggatctgaacctgggagtggaggagaagacgggccca atgcaggtcgatctggaggcccacaacaacgtgacagaggccagcctgattgttgttgtc cacctggaggagcccctcagaggactggtggtgcagccacaccctgcacacagagttctg atggagtcagttgtgagctacacagcgtctgtgcgtgaaggctccagtcccacatttaag tggacagtggatgacaaaccctacttcacctattacaacactgttctcaatgtcatctac cagcacgctgctgtctacaagctcacagtgacggccatgaatcatgtcagcgccctcaca gagcatttcaacgtgacagtggaccgcctgcagcccatggccgacctcactgtgaggggt gtgccagatgtggtcccacagggctccactcagaccctcaccacttcggtgctcatcgac acgtctgtggccgccaccttccgatggtcttttggtgacgggggatacaaggagtttgaa tacaagcctccctatgaccccactctcctctgcccagactcgcccaatcaggtcctccta agcaacaatgtcacctatatctactctcagccagggatatacactgcactggtgtcagtg tccaatcgttatgacaacatcagtcagagtatcaacatgagtgtctacagcatcctgact cgtgttgatatacaaacagagccacgtctcctcctcgctggcaaatcagctgattttgag gctcatcctctgccatcaccctatggaattcactatgactggcactttggagatggttcc accccgctgcaaggtcgccgcgtggcgcacacctatgcacagagtggcaccgtaaatgtc tgtgtgtcagtgaacaacaccatcagttccatggaggcttgtgctgagatgtttgtacat gagaggattgaggatctaagagctgaaagctcatctcccaccgagcttcacagtcccact actgtgcgggcgcaccttgcttcgggtaataacatcacatggacgttctccatgggcgat ggaactatctattctacatctgagcctcacgtgacacacagctacatcgaagatggcaac tacacagtaaacgtgactgctgcgaacgccgtgagctttgtttggacaatcctaccagtg caggtgtttgtcttccaagttataaggatggagccatttgggtgtgtccaagagcagacg cctgtcaactttcaagcctgggtttccggtaacgaatcagctcatctttatgaatggtgc ttcggggatggaagctccaatgagacgcaccacggcaaccccagagtgtcacacacctac ttgacaagtgggaactaccacctctccctgcttctttccagcagggttaacagtgccacc aaggccaacttcttcaactgggtgtgtgtgcagccagctctgaccaacattagcctcacc cttgtgaaactgcactacgcagtcggagaagagatcctgttccaggtcaaagctgagccg gagtttaactacagttatcagtgggactttggtcgagaggaagaccttgtgcctggccac ggttctgggaatattttgacgatgtataaaaacccaggtcactacatggtgacagtcatt gtcttcaacaacatctcctgcagtaataccagtgttgtgattgaggttctgatgcctgta ggaccaattgtaattcaacacaatgggaccaagtacaacaaccttacgcttaaagcagca tatgctttcacaacttcttccttggcatccaatgtcagttacacctggaactttggagat ggaaatctgtttactggtcagaatacccaccacacctacaatatctcaggaatctacaat gtcactctgacagcagccaacacagttagcaggaatcacactactttacctgttgctgtg ctggcaccaatccgtgggttgaccgtcaacgccagcttggttaatgtccccctcaatgcc tcggttcacttcgaggcccaaatggaggaaggagatggtgtcaggttctcttggatcttg tgtgatcgctgtacctcaataccagggacccacaccatgttttataccttccgctctgtt ggcactttcaacatcattgttacggcagaaaatgacgtaggaacggcacaagcgagtatc ttcctgtttgtacaacgtgagctggagggactgcagatattagcggaggaggagatctgc ggaggcacaagagtggacggttgctgctttgctacaaaccgcgttctccaccttcaagca ggattaaaggaaggaaccaacatgacatttacttggaacctcctcagagagcttgaccca gtcggctcgagcttcaacgtaagcggaaagactgtggaggtgaatttctctacaccaggt ccatgtgaaatctttcttcgggctgccaacctcctgggccagctgtctgtcaatagaaca atacacttcttggaaccagcccgaggggtcttcctgcaaatcagcaacaacccagttgca gtcgattctccgactaacctgacagtcctgactatggagggctcagacctgcagtatcac tggtctgtgaatggggacactctgccgtggaacaagccctggaagacccacaccttcatc agtcccggtcaaaaactagttactgtgaaggtctttaatgaagttagctcagaggttgtg tcacagaatgtcagtgtccaggagatcatttctggactaagattcacagctaccaatgtg gaagagcagagttatgtggcaacgggcgtcagcgtcacactccagggagaggtactgaca ggaaccgatgtgacgtggacgtggctgttagatgggagaacagacacgggaaggagaact tctctgattttccaggagccaaagacagccattgttactctgaacgccaccaacgatgtc agtgggcaagtggtttccagggagttctttgctcaagacaaaattcaggggttggagctg agggcaagtacaaagattgctgcagtcggtgagaaagtggagttcaccatttccatggca gggggttcagacgtttgtctgatcctcagcatcagtggagacgccactgttatcactcaa cccaaccacacctatgtccacgtgttcagcagggtggatacctacatggtgaatctcact gctcacaacaaggtgagctccaagaggcggcaactccaggtcgaggtgatggagccagtg cgtgaactttccatcctgggaagcagcgcagcaatccctgtcggtgtgaagaggttgttt gtggccaacatcctgacgggtaaacctgttcatttcctgtggacttttgatttacaccac ctccaccggaaatcacatattggcaaagaggtgtcctacaccccggaagaggcaggatta ttgaccatctacgtgaaggtcttcaacgcgctgcatgcccagaacatcaccaagcacatc ctagtgcagaacctgctcacggctgccatcctgtatgcagcacctcaggacacgttcatc aataagatgataaccctcatggcctctatcacacccaggtcgaattctgtggagtgtttg tgggactttggtgatggttctactccagttcacaccaataaaacatctgtgggttatgag tacagacacccaggacactacctggtccaagtgaactgcagtaacctggtgagctgggtg ttggcccaggtggaagtagacatcagtgtgttagagtgtgaggaaccagaggtgcaggtg cttcaagccccccgtctggccatctggcgctcccagcccactttggtggaggccggcgtt gatctgaaaggctgcatacgctacggagctcagtacctctggcagatactctcgacaccc tcctgtgatagtgacaaagatgaccggattacctctggagcggtgtcgcagccctctcgg tctttgctggtcccagtgatgcgtctgccagtggaggtggatgtgcggcgactgcagctc tcattgcccaagatggctctggcgacaggaaactacagcctggtgttttctctgtcatac gaaggtgtgcctctcaggaaggctgcctgtctgcagctgagtgtcatggctgccaggctg atgcccatcatagaggggggcacctacagggtgtggtcgaggacgcaggacctgcagctc agtgcggagcagtcctatgaccccaacttggatccacacagccagtcactactccactac cactgggactgtcaaagcacctccaagggtccagagcactgctccagtttgaacttcggc ctgggctccagtggtccagtgctgggaatctctggctccgagctggaggcgggcgttgaa tacactttcaaactgaccatcagcaaagaaggcatgccaccagagtccaccacacagact gtgttcgtccagagtggtcacatccccatggtgtatctggagtgtgtgtcctgtaaggcc cagtccatctatgaggtcagccagaactcgtatgtctacctcagagggacctgcaccaac tgccagggctttcaccgtgggcgctggagtgccatgacactgaagaatgaggctctggtg ctggactcctcctccaccaccactggaagcgacggcatgaacctggtgctgcggcagggt gtcttgcgccacatagactcctacatcttcaccctgcacgtgaccgacagcagtctggat ggcgagggcgtcgcctccatcacgctgcaccacaatacggccccggccggtggggagtgt catctgagaggtggagggcaagcgggagtggagtacggggacggagatggtgaagcttgg aggctacgcacactgctggaccgggtacacttcaactgctcaggttacagtgatcgaggg gtctcagagtctcccttgctctacagtctgctggtgacgcgctgcagagaagactactgc gaggacttctgtgtgtacaaaggcagcagtccagagcactcggccttcctgccaccaggc ttcagatcagcccgacatcgtgtagcagtgtccatcacagtggaggaccatcagggagct gccatcacggcactcgacaagaccgttgaagttgtgctgccagaccctccctctggctat agcagccttccccactggctgtctcagctgacggacagcaaactgaaaaagctgctggag cagggagactcccagagggtcagagagctatcactggcccttattacagtcctaaatgag tatgagcagaccagggaatcagcacgggtgtcccgagaggagcgtggttaccgagtccga gtccgcagcaacatcaccagagctctgacggcgctggatctgaccactgttaacgacatc cagcagacttctgctgccctggcacagtgcacggcggtgagccgtgagttcatctgcgag gagtgtcagaacagcactctgaacaagctggagtccatgctggagattttgcagactgac accaagcaaggcaccgtgactccgactgagatagctgacaacatcctgaacatcatgggc gatctgatccatcaggtcagccagtcagcctcccagtcttatttccagtctgcctatgtg gactccccctcacctgccaacaactccttttcctcctctggggaggagcatggaggcgcc ctgttagacccctcgccctcctcattagagccacatcctctgcgtgtggcggcgaaggcg tacagcctgtcctccgtcctcatgctgatcctcatgcatgcccgggtgctcaacgaggag ccgctggtgctgaggggagccgagattgccgccacaggaaaactggcagacccccagagc ttgctctgctaccatggcaacaacagtccagagtgccagcggttctccatcccacgagct ttcaaccacagtctcggcagagctgctgcaggaaacagtatcatgcagctactgtttcag gtggagtccaaccccttccccttcaattatgtggcgaactacaccgtctctactgaggtg gcatccatggagttccgcactgaaaatggcacccagatcccaatctcgggactggacgac aacctagccatcaccgttgccatcaacaacggcagcaatggagaagtgggcgtggagggt tcaggtggcggagggctgcccactgctggagccattaacatcagtcactgtgactctgtc gtcgtcagggtcagcacgggcaacacaaacagacaggcggggctgtttgtgcagctcaac ttcacctctctggaggatgccagagagaaggataacagagtagaggatgaagtggagcca cacatcacagcttaccttaattcccatgaagggccaagcgagttcaattgcacagacaga aagcgtatcacactcagtatgaccagggggcaagacctggaccacaagaaatacaccttc ttcctgtcgccagagttgtacgacaccacactggactacttcatcaatgtgagtacgccc tgcagccctggctctcggcctgtgggtgttcgtctggaggtgggggtgtttgcctccctg tgtcagtacttcagtgagagcgagaagcagtggcggacggatggcatggtgcccctggca gagactaacgccagcagagcagtttgccgcacaaggcacctcacctcctttgctgcgggc ctgtttgtgccgaccaacgccatcagcttcatagcgccagagcgttctggtccaccaagc ctggtcgtgctgttggtgtgtgtgttgggcttactaagttatgttgtggcagcagccatc ttgcacaagttggaccagctggatctacgccgggccggtgtggttccactctgcggccaa gacggtctcttcaagtacgaggttcaggtcaagactggttggagtcgaggggcaggcacc acagctcacgtgggaatcaatttgttcgggcacgagagccgcagcggacaccgacatctc gacagcagaggagccttctcacgcaatgctcttgatatcttccacattgccacagactca agcctgggcagtgtctggaaactacgaatatggcacgacaacaagggtctgtccccagcg tggatgctacagtacgtcttggttaaagacctgcaaacagggagcagctacttcttcctg gttgaggagtggctgtccgtcgacaatgaaagaaccgatggacgagtagagattgaggtg gaggcgtcagaggaggctgtgcttcgccaggtgccccgcctcgcgtggtgcgagttgcag agggcgctgtgtgagagccacctgtggctgtcactgtgggagaggcccccccgcagcccc ttcacccgcctccagagagccacttgctgcactgtgttactgcagctgtttctattggcc aacacactgtggtacagcatcgtggtggacaagagacacagcccccgggccgtgtcgagg ctttccacattaaatggagagactgtggcagccggtgtggtgacctgtctgattgtctac cctctatacctgctcgtcttcactctcttccgaatgagccgaagcaagtgtgtgtctgtg gagcaggtaccacctcaagtggaccaggagtctgtggagattgatgacttcctcgagaac tcaatggctggaagttccttcctcttttataatggcgagaccaattcagaagaaaccaat gtcgatttgcccactccatcaaccaaaagtgtggatagttggaccatggcggaggaggag acggaggacagggattggccggagctgttgagtgacgtgtctgtggtgggaggggcggga catggagcgggacttcccagactgaagaggggtcaggggagcaggcacctgggtgtcgac atgacctttaaccctgacgaagacgagggcactgaccaacgcaacaaatatttcacctcc tcagatgaggatctaatcaaacacatcctgacagacgggcagaacttctttcctcaggcc gatgaaagtgagatggctgacctgtcgagcatttttggagacaaaactgaagtgattctc ctccagaagctgaatgagcctcttcctctagaatctgtcagaagggacccaccaaaaact gctttcacctctaaaacagttgtgacagacgtatgtcgtcccaggcggttccctccctgg tgtggtcgtgccaccctgtggggcagctgggcgggaatcgccctggcgaatgccgtttcg atttgggcggcccacgggttcagtcaaaatgtggccatgatgtggctcatctcctgtttt gccagtttcctgtgctcatgcctgctgttggagccaatcaaggtgctgtgtgaggcagtg tactatgcagtgtttgtgcgtcgcctgcgtccagaggaccaggacgtgctggtggagttt ccccgtgtggagagagtggttcagagggtccccagggtgagaccaccgcagggctttgct ctgtcccaagcacggcaccaggcccgcaaggtccacatgctgcacaccatgctgaagaat ttcctggtttatatgtttttcctgttggtggttttacttctcaactactctgactccgcc aaagacacacacagcctgagactgcgcaatcagctgcaacaagccctacacacacctgag tatcacaacatccacagccgagatgaggttttcatgtggctgaatgagtccctgttgcca cggttactggaggactctgctctcctgagagacacaggaactgtgttacttggcaccctg aggctgcgacaagtccgtgacacacaggttgcaggtggtgcgtgggcaggagacagtgtt tggagtaagggctggtttacccctctaaataaagatgctgagaatttcaccgattttggt gctagccatgcaaatggggtgtggcgtttgggtcaagtgagggtgcataacagcggtgat gtggtccagcagctgaaccggagcctggaggaggcctcttcctccttacagcagctgagg cagctgcactggctcgacttcaggactcgcgcagtgtttgtggagttctcactctacaac atcaacacaaacctcctggctgtcttctccttcctgtttgagttcccggtttctgagcgt gccctgtccagtcttgacctccatgtcatcactctgtggccaatcataagcctggacctg cagctccttctcacgatcattctcctcatcctggtgttgtacttcctggtgcgggggatc ttgggcttcctcagagagggctacaggtacctgctgtcagcctggagactcctgggcgtc tgtaaactgacgctggcagcatttgtgtgcgggctgcacctgagccgctgcaccatggcc aagaatcagtggacgttgtacatgaagcacccgcgggacgccttcacagatttctacccc ctggccaggcagagccaaatgtacacagtcatgtctgcatggctgttgttcattctggtg ctcaaggcgtcccaccagttgcggtttctccgagagtgggctgtgtttggcagagctctg cggcgctcggtctgggagctgctgggagtcgccctggcattactgctgttgatgctggcc tactcacacacaggacacctgctcttccactctgtactggacggctatgacagtgtgagc tccgccggtctgtctctgttgggtgccggtgggcgaggcctgttatcgtggcgacccggc tggacgattaccggaccctctaacacagtctcctcactggtattccacgcgagcttcgct gtatttcggctggtgttgctttggttgatcacttccgtgctcctgaggaattaccgccgc gcgcgagctgagctgtaccggcccgctgtggatctgcaagactacgagatggtcgagctg ttcctcagacgactcaaaatgtggatgggactcagcagggccaaggagtttcgtcacaag gtgcgtttcgaaggcatggagctgccaccgtcccgctcttcgtccaccagcgactgtaag tccctgtgcttgccaccactggatggtcccgactctcctcccacaccagacagtgttgac gctggctccgaggcctcgtggcgcccggcctcttccagcccctgcagtctgacagaagcc ccagggatcggcttggggcttggcttgggcctgggtttgggccttggccccagagtggtg gtgggcggtaccagttggagggagagggcagagactgaggcctctctgaggaggctgctt cctaccctggatgccctgctgcaacagcttgatcgcgtcaccatggcaacagaggatctg taccacatcgagtgtagactggagcgagcccagaggaaaaggaggcgtagagggagagag agaggaggaggtggtggccagagagggaagggtgacgacaaggactctgctggatggaga gagcggaagagtggcaaagaaaaacacaaagggagcaagaaggggaaaaaggactgtgga aacactgctgccaacccaaaaaagactcctgtagccacaccggttccctttttgaagccc agaccaaccttggcttcgacacacacccctgctcctcagtcatcagccaaaccctcagtc agtgcaccaccacccacaccagtctcagataagtctgcttctgactcctcctccctcccc gtctcgacagcaaacactccccctacccatgtcccaatgcccaagacaccaactgcacct ccatgtacccctgcgccttgtctgccttccactcctgcctctacacccatcacccgggac tgggaccctcccagagagaaagagaccctccccgcctccagcctgttcaaccaccccgct cacacaaccaccattcccacacgcaagcgaaaacgcaagcctccgccactcaaaaataag gtgcaccccaacttagacaggcacggctccggacaccccaaatcctga

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