Shewanella mangrovisoli: K0H60_06100
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Entry
K0H60_06100 CDS
T09316
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
smay
Shewanella mangrovisoli
Pathway
smay00260
Glycine, serine and threonine metabolism
smay00261
Monobactam biosynthesis
smay00270
Cysteine and methionine metabolism
smay00300
Lysine biosynthesis
smay01100
Metabolic pathways
smay01110
Biosynthesis of secondary metabolites
smay01120
Microbial metabolism in diverse environments
smay01230
Biosynthesis of amino acids
Module
smay_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
smay_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
smay_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
smay00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
K0H60_06100 (thrA)
00270 Cysteine and methionine metabolism
K0H60_06100 (thrA)
00300 Lysine biosynthesis
K0H60_06100 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
K0H60_06100 (thrA)
Enzymes [BR:
smay01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
K0H60_06100 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
K0H60_06100 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF1131
Motif
Other DBs
NCBI-ProteinID:
QYK10259
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All DBs
Position
1379685..1382153
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AA seq
822 aa
AA seq
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MKVMKFGGTSLANWQRFSMAADIVAKAAKAESVATVLSAPATVTNALLEMVDVAVKGEDY
SPVIQHVERVFTSLYQDAVGSGLSSSQSEVLFAGLSAQLARWQDRLRGITLLQECPDGVR
AEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGRPLESVVDIAVSKPRFKNLAL
DEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV
VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA
DESGLQVKAISNLDNQTMFDVSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSIS
FCVATSDAAKVKSALEQEFELEIKSDLLEPIEMRHDLAIVSLIGDGMRTHKGVAARFFQA
LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG
LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQSSDLPALLA
WVKEQQLLNPVLVDCTSSDQVSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQ
RRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGKLDEGMTLSEATKL
AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM
ARLPEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAF
YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atgaaagttatgaaatttggtggtacctcgcttgcaaattggcagcgattttcaatggcg
gcggatatcgtggccaaggcggcaaaagctgaatctgtggctacagtgctatctgcgccc
gcgacagtgacaaacgccttgctagaaatggtcgatgtagcggtgaaaggggaagattat
tcgccagtcattcaacacgttgaacgggtgtttacctcgctctatcaggatgcggtcggt
tctggactctcgagcagtcaaagcgaagtgttgtttgccggactgagtgcgcagcttgcg
cgttggcaggacagattacgcggtattacgctgctgcaggaatgccctgacggggtgcgc
gccgagatcgtggttgccggtgagcgtttgtctgctgcgttgatggagcaagttatgctg
gccaaaggcatcacttcggcgcagctggacccacgtgagctgtttttaggccgtggtcgt
ccgctcgagtccgtggtggatattgccgtcagtaaaccgcgattcaaaaaccttgccctc
gatgagaagcgggtttgggtgatgcctggctttactgccgccgatgaagacggcaaggtt
gtgaccttaggccgtaatggttctgactattccgctgccgtgctggccgcttgtttagat
gcttcaagctgcgagatctggaccgacgttgacggcgtatacaacacagatcctcgggtt
gtcaccgatgctaagttgttgtcgcaactcagttatcaagaggcgatggagctgtcttac
tttggggctaaggtgctgcaccctaaaaccattgcgcccatcgcgcagtttcatattcct
tgttatatcaagaacagctttaaccccgatgcgcccggcactctggtatcgaatcaggcc
gatgaaagcggtttgcaggtgaaagccatttctaatctggataatcaaaccatgtttgat
gtatcaggccctggcatgaaggggatggtcggcatggctagccgcacgctggcggcaatt
tcccgtagtggcgtttccgtgtcactcatcacccagagttcttgcgaatacagcatcagc
ttttgtgtggcgactagtgatgcggccaaggtgaaatcggcgctggagcaagagtttgaa
ctagaaatcaaaagtgacttactcgagccgattgaaatgcgccatgacttagcaatcgtc
tccttgatcggtgatggaatgcgtacccataaaggtgtggcggcgcggttcttccaagcg
ttagcgcaggctagtgtgaatattatcgcgattgcgcaaggctcttctgaacgttctatt
tcaacggtaatcgagcagcgaaagaccaaacatgccgtagccgcctgtcatcagggcttt
ttcgatgtgcagcaatatttggatgtgtttttagtgggttgcggcaatgttggtgcaggc
ttactcgagcaaatcaaacatcaggcgagcgtgttaaaagagcagcacattagcattcgt
gtctgcggcatagtgaattcaagcaagatgttactcgatagtgcgggtatcgatttaaac
aattggcaaaacctgcttgccgacagtcagcagtcaagcgaccttcccgcgctattggct
tgggtgaaagagcaacagttattaaaccctgtactggtggattgtacttcaagcgatcaa
gtgtcaaaccagtatttagaggtaatgaatgcgggcatgcacgtggtgacgcccaataag
aaggccaatactcgagactacgcttactaccaagcactgcgtcaaacagctttgaaacaa
cgtcgtcagttcttgtatgagactaacgttggcgccggattacccgttatcgacaacttg
aaaaaactgttatttgctggcgataagttgcacaagtttaacggtattttatcaggctcc
ttatcctttatcttcggtaaactcgatgagggcatgacactgtcagaagcgactaaactg
gcgcgggaaaaatgctttaccgagcccgatccccgtgatgatttaagtggtatggatgtg
gcgcgtaaagtgctgatcttggcccgtgaagtgggtttgaaacttgagctaagcgatatc
gttgtcgactcagttctgcctgacgattttgatgattcaggcgatgtggaaagttttatg
gcgcgtttacccgaggcagatgccgcgattgcggcgcgagtggcagaggcgaaagcacag
ggcaaagtgctgcgttatgtggggcagattgaagaaggtgcgtgttatgtgcgtatcacc
gaagtcgatgccaccgatccgctctacagcgtaaaaggcggtgaaaatgccctagcattc
tacagccgttattatcagccgattccttttgtgctacgtggttatggtgcgggtacagaa
gtgacagcggccggcgcttttgccgatgtattaagaaccttaaattggactcgtgaggtg
agtgtatga
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