Streptococcus mutans NN2025 (serotype c): SmuNN2025_0725
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Entry
SmuNN2025_0725 CDS
T01185
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
smc
Streptococcus mutans NN2025 (serotype c)
Pathway
smc00290
Valine, leucine and isoleucine biosynthesis
smc00620
Pyruvate metabolism
smc01100
Metabolic pathways
smc01110
Biosynthesis of secondary metabolites
smc01210
2-Oxocarboxylic acid metabolism
smc01230
Biosynthesis of amino acids
Module
smc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
smc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SmuNN2025_0725 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SmuNN2025_0725 (leuA)
Enzymes [BR:
smc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SmuNN2025_0725 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IF-2
Motif
Other DBs
NCBI-ProteinID:
BAH87751
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All DBs
Position
762961..764526
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AA seq
521 aa
AA seq
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MRKVEFLDTTLRDGEQTPGVNFSIKEKVAIAKQLEKWGISDIEAGFPAASPDSFEAVKQI
AAAMTTTAVSGLARSVKSDIDACYEALKDAKFPQCHVFIATSPIHREFKLKKSKEEILEV
IKEHVTYARSKFDVIEFSPEDATRTELDFLLQVVQTAVDAGATYINIPDTVGFTTPVEFG
HIFKYLIENVKSDRDIIFSPHCHDDLGMATANTLAAIKNGAGRVEGTVNGIGERAGNVAL
EEVAVALNIREDYYDATSAIVLDETVTTSEMVSRFSGIPVPKNKAVVGGNAFSHESGIHQ
DGFLKNPLTYEIITPELVGVKKSSLPLGKLSGRHAFIEKLKELKLDFEEGEVAPLFAKFK
SLADKKHDITDADIRALVAGTSVENPEGFHFKDLRLTSNDDDTITAQVIMVNEGEEEVTI
IANGKGSVEAIFNAVDKFFNQTVKLDSYNIEAVTDGIDAQARVLVSVENVDTDTIFNASG
LDFDVLKASAIAYINANTFVQKENAGEIGHKVSERDYPSND
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgcgtaaggttgaatttcttgacacaacgctccgtgatggcgaacaaacaccgggggtt
aatttttcgattaaagaaaaagtagctattgccaagcaattggagaagtggggaatctct
gatattgaagccggttttccagctgctagccctgactcttttgaagctgtgaagcaaatt
gcagcagcgatgacaacaactgctgtatcaggtctggctcgttctgtgaaatctgatatt
gatgcctgttatgaggcacttaaggatgccaaatttccacaatgtcatgtctttattgca
accagtcctattcatcgtgaatttaagcttaaaaaatccaaagaagaaattcttgaagta
attaaggaacatgtaacttatgcgcgctcaaaatttgatgtgattgaattttcaccagag
gatgccacacgtacagaacttgatttcctattgcaggtagtgcaaactgctgtagatgct
ggcgctacttatattaatatccctgatacagttggctttaccacgccagtagaatttggt
catattttcaagtatctcattgaaaatgttaaatctgaccgtgacattattttcagccct
cattgtcatgatgacttgggaatggcaaccgctaataccctcgctgccattaaaaatggt
gctggacgtgttgaaggaacggttaatggtatcggagaacgtgctggtaacgtagctctt
gaagaagtggccgtagctcttaatattcgtgaagattactatgatgcgaccagtgctatc
gttcttgatgagacagtgaccacttcagaaatggtatcacgtttctcgggtattcctgtt
cctaaaaataaagctgttgttggtggcaatgctttttcacatgaatccggtattcatcaa
gatggttttcttaagaatcccctcacttatgaaattatcacgcctgaattggttggtgtt
aagaaaagttccctgccgcttgggaaattatctggccgtcatgcctttattgaaaaatta
aaagaattgaagcttgattttgaagaaggagaggttgcacctctttttgcaaaatttaaa
tcgttggccgataaaaaacacgatatcacagatgctgatattagagctttggtagcaggg
actagtgttgaaaatcctgaaggtttccactttaaggacttaaggctgacatcaaatgat
gacgacacgatcacagcacaagttattatggtcaatgagggtgaggaagaagtaactatc
attgctaatggtaaaggttctgttgaagctattttcaatgctgtcgataaattctttaat
caaactgttaagttagatagttataatattgaggctgttactgatggtatcgatgctcag
gcacgtgtgctcgtttctgtggaaaatgttgatacggataccattttcaatgcttctggt
cttgactttgatgttttaaaagctagtgctattgcttatatcaatgctaatacctttgtt
caaaaggaaaatgctggtgaaattggtcacaaagtttcagaacgtgattatccaagtaat
gactag
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